Category: 38939-88-7

On November 1, 2019, Zhu, Xiuquan; Liu, Jiawei; Zhang, Qunfeng; Li, Xiaonian published a patent.Application of 38939-88-7 The title of the patent was Stable and efficient method for preparing arylamine by catalytic hydrogenation. And the patent contained the following:

The title method includes adding stabilizer (acetic acid, boric acid, etc.) into reaction solvent, performing catalytic hydrogenation aromatic nitro compound represented by formula (I) and hydrogen gas under the action of catalyst to obtain aromatic amine. The catalyst is prepared by (1) preparing mixed solution of precious metal compound (H2PdCl4, Pd(NO3)2, etc.), Cu-containing compound and furfural; (2) dropping into activated carbon, and stirring; (3) vacuum drying at 20-30°C for 4-20 h; (3) repeating step (1) and step (2); (4) reducing under H2 atmosphere at 50-80°C for 3-10 h. The invention has improved stability and product yield. The experimental process involved the reaction of 2-Chloro-4-methyl-1-nitrobenzene(cas: 38939-88-7).Application of 38939-88-7

The Article related to aromatic amine preparation hydrogenation intro compound catalyst, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Amines, Amine Oxides, Imines, and Quaternary Ammonium Compounds and other aspects.Application of 38939-88-7

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On August 20, 2006, Han, Jung Hwa; Choi, Jin Woo; Choi, Kyung Il; Kim, Joong Hyup; Yoo, Byung Woo published an article.Synthetic Route of 38939-88-7 The title of the article was A facile and efficient reduction of nitroarenes with the NiCl2·6H2O/indium system. And the article contained the following:

The reactions of the NiCl2·6H2O/indium system with various nitroarenes proceeded with high yields to give 82-95% anilines and showed selectivity over other labile substituents. Among the 12 anilines prepared were 95% o-aminoacetophenone, 94% p-chloroaniline, 92% m-bromo-p-aminotoluene and 91% p-aminophenylacetonitrile. The experimental process involved the reaction of 2-Chloro-4-methyl-1-nitrobenzene(cas: 38939-88-7).Synthetic Route of 38939-88-7

The Article related to nickel chloride hydrate indium reducing agent reduction nitroarene, chemoselective ultrasound reduction nitroarene preparation aniline, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Amines, Amine Oxides, Imines, and Quaternary Ammonium Compounds and other aspects.Synthetic Route of 38939-88-7

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On December 31, 2000, Ivanova, E. V.; Grabovskii, S. A.; Kabal’nikova, N. N.; Shereashovets, V. V. published an article.COA of Formula: C7H6ClNO2 The title of the article was Reaction of dimethyldioxirane with aniline hydrohalides. And the article contained the following:

Oxidation of aniline hydrohalides RC6H4NH2·HX (I; R = H, 3-Me, 4-Me; X = Br, Cl) with dimethyldioxirane (II) resulted in a variety of ring-halogenated anilines, nitrosobenzenes, and nitrobenzenes depending on the II/I ratio and other reaction conditions. Mechanism of this reaction was suggested. The experimental process involved the reaction of 2-Chloro-4-methyl-1-nitrobenzene(cas: 38939-88-7).COA of Formula: C7H6ClNO2

The Article related to dimethyldioxirane aniline hydrohalide oxidation, haloaniline halonitrosobenzene halonitrobenzene preparation, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Amines, Amine Oxides, Imines, and Quaternary Ammonium Compounds and other aspects.COA of Formula: C7H6ClNO2

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On April 15, 2022, Song, Heng; Shen, Yang; Zhou, Hu; Ding, Danli; Yang, Fu; Wang, Yemei; Xu, Chen; Cai, Xingwei published an article.Recommanded Product: 38939-88-7 The title of the article was Light-Promoted Low-Valent-Tungsten-Catalyzed Ambient Temperature Amination of Boronic Acids with Nitroaromatics. And the article contained the following:

A low-valent-tungsten-catalyzed reaction that enables the ambient temperature amination of boronic acids with nitroaroms. was disclosed. With readily available W(CO)6 as a precatalyst under external-photosensitizer-free conditions, nitroaroms. smoothly underwent C-N coupling reactions with their boronic acid partners, delivering structurally diverse secondary amines in good yields (>50 examples, yields up to 96%). This methodol. is both scalable and highly chemoselective and engages both aliphatic and aromatic boronic acid partners. The catalysis was initiated by the deoxygenation of nitroaroms. by a trans-[W(CO)4(PPh3)2] (trans-W, PPh3 = triphenylphosphine) complex, which formed in-situ via ligand replacement. The experimental process involved the reaction of 2-Chloro-4-methyl-1-nitrobenzene(cas: 38939-88-7).Recommanded Product: 38939-88-7

The Article related to nitroarene boronic acid tungsten catalyst chemoselective photochem amination, aryl amine preparation, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Amines, Amine Oxides, Imines, and Quaternary Ammonium Compounds and other aspects.Recommanded Product: 38939-88-7

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On August 31, 2002, Yoo, Byung Woo; Lee, Sung Jae; Yoo, Byoung Seung; Choi, Kyung Il; Kim, Joong Hyup published an article.Electric Literature of 38939-88-7 The title of the article was A facile reduction of aromatic nitro compounds to aromatic amines with bis(cyclopentadienyl)titanium(IV) dichloride-indium system. And the article contained the following:

Cp2TiCl2/In system was found to be a new reagent for reducing various aromatic nitro compounds to the corresponding aromatic amines in good yields under mild and neutral conditions. The experimental process involved the reaction of 2-Chloro-4-methyl-1-nitrobenzene(cas: 38939-88-7).Electric Literature of 38939-88-7

The Article related to aromatic nitro compound reduction cyclopentadienyl titanium indium catalyst, aryl amine preparation, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Amines, Amine Oxides, Imines, and Quaternary Ammonium Compounds and other aspects.Electric Literature of 38939-88-7

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On September 30, 2003, Yoo, Byung Woo; Choi, Jin Woo; Hwang, Sun Kyun; Kim, Dong Yoon; Baek, Heung Soo; Choi, Kyung Il; Kim, Joong Hyup published an article.Electric Literature of 38939-88-7 The title of the article was A facile reduction of nitroarenes to anilines using FeCl3·6H2O/indium. And the article contained the following:

Reduction of a variety of nitroarom. compounds to the corresponding anilines occurs chemoselectively in high yields upon treatment with a new reduction system consisting of FeCl3·6H2O/indium in aqueous methanol. The experimental process involved the reaction of 2-Chloro-4-methyl-1-nitrobenzene(cas: 38939-88-7).Electric Literature of 38939-88-7

The Article related to nitroarene reduction iron chloride indium catalyst, aniline preparation aromatic amine, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Amines, Amine Oxides, Imines, and Quaternary Ammonium Compounds and other aspects.Electric Literature of 38939-88-7

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On December 8, 2017, Wang, Yingdong; Li, Shibin; Zha, Yanji published a patent.HPLC of Formula: 38939-88-7 The title of the patent was Method for preparing 2B oil by catalytic hydrogenation. And the patent contained the following:

The invention discloses a method for preparing 2B oil by catalytic hydrogenation. The method comprises the steps of: adding water and chloro-4-methylnitrobenzene at the weight ratio of 1:(3-10) to a hydrogenation reactor, regulating pH to 8-9 with sodium hydroxide, then adding carbon-supported platinum catalyst that is no less than 1% of total mass of the system, performing replacement with nitrogen, heating to 70-75 °C, introducing hydrogen, controlling the reaction pressure at 0.7-0.8 MPa, reacting until there is no hydrogen absorption, discharging the material after the reaction, layering, and rectifying to obtain 2B oil. The method prepares 2B oil by hydrogenation reaction between hydrogen and chloro-4-methylnitrobenzene under the action of the metal catalyst, saves energy, protects the environment, and has low unit consumption for production and high quality of product. The method has the nitro conversion ratio of 99.61%, dechlorinated product content as low as 0.16% and residual nitro compound content as low as 0.03%. The experimental process involved the reaction of 2-Chloro-4-methyl-1-nitrobenzene(cas: 38939-88-7).HPLC of Formula: 38939-88-7

The Article related to chloromethylaminebenzene preparation hydrogenation, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Amines, Amine Oxides, Imines, and Quaternary Ammonium Compounds and other aspects.HPLC of Formula: 38939-88-7

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Tanini, Damiano; Dalia, Camilla; Capperucci, Antonella published an article in 2021, the title of the article was The polyhedral nature of selenium-catalyzed reactions: Se(IV) species instead of Se(VI) species make the difference in the on water selenium-mediated oxidation of arylamines.SDS of cas: 38939-88-7 And the article contains the following content:

On water selenium mediated oxidation of anilines was reported. In the presence of di-Ph diselenide or benzeneseleninic acid, anilines reacted with hydrogen peroxide, providing direct and selective access to nitroarenes. On the other hand, the use of selenium dioxide or sodium selenite lead to azoxyarenes. Careful mechanistic anal. and 77Se NMR studies revealed that only Se(IV) species, such as benzeneperoxyseleninic acid, were the active oxidants involved in the catalytic cycle operating in water and leading to nitroarenes. While other selenium-catalyzed oxidations occurring in organic solvents were recently demonstrated to proceed through Se(VI) key intermediates, the on water oxidation of anilines to nitroarenes does not. These findings shed new light on the multifaceted nature of organoselenium-catalyzed transformations and open new directions to exploit selenium-based catalysis. The experimental process involved the reaction of 2-Chloro-4-methyl-1-nitrobenzene(cas: 38939-88-7).SDS of cas: 38939-88-7

The Article related to aryl amine water selenium catalyst oxidation, nitroarene preparation, arylamide preparation, azoxyarene preparation, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Amides, Amidines, Imidic Esters, Hydrazides, and Hydrazonic Esters and other aspects.SDS of cas: 38939-88-7

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On October 5, 2018, Peng, Jingjing; Zhao, Lifen; Wang, Lanlan; Chen, Hui; Qiu, Yunguang; Wang, Jiang; Yang, Huaiyu; Liu, Jun; Liu, Hong published an article.Recommanded Product: 38939-88-7 The title of the article was Design, synthesis, and biological evaluation of 2-(phenoxyaryl)-3-urea derivatives as novel P2Y1 receptor antagonists. And the article contained the following:

A novel series of 2-(phenoxyaryl)-3-urea derivatives I [R1 = H, Me; R2 = n-Bu, 4-F3COC6H4, 5-methoxycarbonyl-2-thienyl, etc.; X = CH, N] were designed, synthesized and biol. evaluated for their anti-thrombotic activity and antiplatelet aggregation study. Most of compounds exhibited good inhibition against P2Y1 receptor among them, compounds I [R1 = H, Me; R2 = 2-methylcyclohexyl, 2-adamantyl, 4-F3COC6H4; X = N] demonstrated good P2Y1 receptor antagonistic potency in vitro (IC50 = 0.62 μM, 0.82 μM, and 0.21 μM, resp.). Four compounds I [R1 = H, Me; R2 = 4-methylcyclohexyl, 4-F3COC6H4, 5-ethoxycarbonyl-2-thienyl, 5-benzyloxycarbonyl-2-thienyl, etc.; X = N] showed good antiplatelet activity. The possible binding modes of compounds with P2Y1 receptor were also explored by mol. docking simulation. The docking studies demonstrated that compound I [R1 = Me; R2 = 4-F3COC6H4; X = N] interacted well with Phe119 through hydrophobic interaction and modestly improved the P2Y1 receptor antagonistic activity. The experimental process involved the reaction of 2-Chloro-4-methyl-1-nitrobenzene(cas: 38939-88-7).Recommanded Product: 38939-88-7

The Article related to phenoxyaryl urea preparation p2y1 antagonist antiplatelet docking sar, 2-(phenoxyaryl)-3-urea derivatives, anti-platelet, p2y(1) receptor antagonist, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Amides, Amidines, Imidic Esters, Hydrazides, and Hydrazonic Esters and other aspects.Recommanded Product: 38939-88-7

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On January 30, 2020, Yasukawa, Keiichi; Sawano, Shota; Okinaka, Keiji; Ogiwara, Toshinari; Shiomi, Takushi published a patent.Computed Properties of 38939-88-7 The title of the patent was Heterocyclic compound, organic electroluminescence element, and electronic device. And the patent contained the following:

The present invention relates to compound I, II or III [R1-R4 = independently Q1, Q2, etc.; with a proviso that at least one of R1-R4 is Q1, etc. and at least one of R1-R4 is Q2, etc.; X1 = oxygen atom, sulfur atom or C(R151)(R152); R101-R110 = independently H or substituent; R151, R152 = independently H or substituent; R151 and R152 may combine to form a ring; substituent in R101-R110, R151, R152 = independently (un)substituted aryl, (un)substituted heterocyclyl, (un)substituted alkyl, etc.; R161-R168 = H or substituent; substituent in R161-R168 = independently halo, (un)substituted aryl, (un)substituted heterocyclyl, etc.; * represents a bond site to carbon atom of benznene ring in I-III]. For example, compound IV was prepared via Pd(PPh3)4-catalyzed coupling reaction of 2-bromonitrobenzene with 4-dibenzofuranboronic acid, cyclization in the presence of PPh3 and treatment with 2,5-bis(9H-carbazol-9-ly)-3,6-difluoroterephthalonitrile. Title compound has TADF property and organic electroluminescent device comprising an invention compound exhibits high EQE. The experimental process involved the reaction of 2-Chloro-4-methyl-1-nitrobenzene(cas: 38939-88-7).Computed Properties of 38939-88-7

The Article related to heterocycle preparation organic electroluminescence element, Heterocyclic Compounds (More Than One Hetero Atom): Fused-Ring Systems With Two Or More Hetero Atoms, No More Than One Hetero Atom Per Ring and other aspects.Computed Properties of 38939-88-7

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics