Category: 38939-88-7

On December 17, 2021, Cheng, Chaozhihui; Xiang, Jian-Nan; Zhu, Yan-Ping; Peng, Zhi-Hong; Li, Jin-Heng published an article.Computed Properties of 38939-88-7 The title of the article was Nickel-Catalyzed Arylcarbamoylation of Alkenes of N-(o-Iodoaryl)acrylamides with Nitroarenes via Reductive Aminocarbonylation: Facile Synthesis of Carbamoyl-Substituted Oxindoles. And the article contained the following:

Nickel-catalyzed arylcarbamoylation reactions of alkenes of N-(o-haloaryl)acrylamides with CO and nitroarenes via reductive aminocarbonylation to produce carbamoyl-substituted oxindoles with an all-carbon quaternary stereogenic center are presented. Starting with N-(o-haloaryl)acrylamides, simple CO, and inexpensive nitroarenes and using a Ni catalyst, a dinitrogen-based ligand, a Zn reductant, a TMSCl additive, and a base system, this protocol enables the synthesis of various carbamoyl-substituted oxindoles and allows the efficient late-stage derivatization of valuable mols. The experimental process involved the reaction of 2-Chloro-4-methyl-1-nitrobenzene(cas: 38939-88-7).Computed Properties of 38939-88-7

The Article related to haloaryl acrylamide carbon monoxide nitroarene nickel catalyst aminocarbonylation, oxoindolinyl phenylacetamide preparation, Heterocyclic Compounds (One Hetero Atom): Indoles, Indolizines, Carbazoles, and Other Arenopyrroles and other aspects.Computed Properties of 38939-88-7

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On February 15, 2018, Giampitro, Natalie C.; Fischer, Lindsey G.; Baum, Erich W.; Crouse, Gary D.; Ward, Andrew L.; Sparks, Thomas C.; Petkus, Jeff published a patent.Computed Properties of 38939-88-7 The title of the patent was Preparation of heteroaryl ureas as pesticides. And the patent contained the following:

This invention relates to compounds I [Ar1 = substituted phenyl; Het = 1,2,4-triazolyl; Ar2 = (un)substituted Ph; R1 = H, (un)substituted alkyl, alkenyl; R2 = H, alkyl, haloalkyl, etc.; R3 = (un)substituted Ph; R4 = H, alkyl, haloalkyl, etc.; Q1 = S; L = a linker selected from (un)substituted (un)saturated alkyl, cycloalkyl] having pesticidal utility against pests in phyla Nematoda, Arthropoda, and/or Mollusca, processes to produce such mols. and intermediates used in such processes, compositions containing such mols., and processes of using such mols. against such pests. These mols. may be used, for example, as nematicides, acaricides, insecticides, miticides, and/or molluscicides. Over 200 compounds I were prepared E.g., a multi-step synthesis of II, starting from 3-bromo-1H-1,2,4-triazole and 1-iodo-4-(trifluoromethoxy)benzene, was described. Exemplified compounds I were evaluated for their biol. activity against various pests (data given). The experimental process involved the reaction of 2-Chloro-4-methyl-1-nitrobenzene(cas: 38939-88-7).Computed Properties of 38939-88-7

The Article related to heteroaryl urea preparation pesticide nematicide acaricide insecticide miticide molluscicide, Heterocyclic Compounds (More Than One Hetero Atom): Other 5-Membered Rings, Two Or More Hetero Atoms and other aspects.Computed Properties of 38939-88-7

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On April 13, 2020, Gan, Haifeng; Cao, Mengru; Wu, Hongli published an article.Recommanded Product: 38939-88-7 The title of the article was Synthesis of 2-Arylbenzoselenazoles from Se-mediated Redox Condensation of 2-Chloronitrobenzene and Arylmethyl Chlorides. And the article contained the following:

A selenium-mediated redox condensation of 2-chloronitrobenzenes 2-Cl-RC6H3NO2 (R = H, 4-Me, 5-F, 5-CF3, etc.) and arylmethyl chlorides R1CH2Cl (R1 = Ph, naphthalen-1-yl, pyridin-3-yl, etc.) to obtain 2-arylbenzoselenazoles I (R2 = H, 6-Me, 5-F, 5-Br, etc.) has been realized under metal-free condition. The reactions proceeded in moderate-to-good yields with good functional compatibility and gram-scale achievement. Primarily mechanistic investigation suggested that key intermediate Bn(Se)nBn II, was first isolated and confirmed by NMR. The experimental process involved the reaction of 2-Chloro-4-methyl-1-nitrobenzene(cas: 38939-88-7).Recommanded Product: 38939-88-7

The Article related to arylbenzoselenazole preparation, chloronitrobenzene arylmethyl chloride selenium redox cyclocondensation, Heterocyclic Compounds (More Than One Hetero Atom): Other 5-Membered Rings, Two Or More Hetero Atoms and other aspects.Recommanded Product: 38939-88-7

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On January 16, 2020, Gan, Haifeng; Macfarlane, Douglas R. published an article.COA of Formula: C7H6ClNO2 The title of the article was Facile preparation of 2-arylbenzoselenazoles from three components reactions: 2-Chloronitrobenzenes, Se, and arylacetic acids. And the article contained the following:

A selenium-mediated decarboxylative cyclization of 2-chloronitrobenzene and arylacetic acids to prepare 2-arylbenzoselenazoles has been established under metal-free condition. The reactions proceeded in moderate to good yields with good functional tolerance and gram-scale application. The experimental process involved the reaction of 2-Chloro-4-methyl-1-nitrobenzene(cas: 38939-88-7).COA of Formula: C7H6ClNO2

The Article related to arylbenzoselenazole preparation, chloronitrobenzene arylacetic acid decarboxylative cyclization selenium, Heterocyclic Compounds (More Than One Hetero Atom): Other 5-Membered Rings, Two Or More Hetero Atoms and other aspects.COA of Formula: C7H6ClNO2

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Shi, Wei-Min; Liu, Feng-Ping; Wang, Zhi-Xin; Bi, Hong-Yan; Liang, Cui; Xu, Li-Ping; Su, Gui-Fa; Mo, Dong-Liang published an article in 2017, the title of the article was Synthesis of 1-Vinyl/Arylbenzotriazole 3-Oxides through a Copper-Mediated C-N Bond Coupling Reaction.HPLC of Formula: 38939-88-7 And the article contains the following content:

An efficient synthesis of 1-vinyl/arylbenzotriazole 3-oxides, e.g., I via the copper-promoted coupling of N-hydroxybenzotriazoles with alkenyl- or arylboronic acids is reported. This strategy features mild reaction conditions, good functional group tolerance, broad substrate scope and rapid introduction of benzotriazole N-oxide moieties into mols. D. functional theory calculations revealed that the formation of the favored N-coupling product depends on the kinetically more favorable C-N bond formation pathway. The experimental process involved the reaction of 2-Chloro-4-methyl-1-nitrobenzene(cas: 38939-88-7).HPLC of Formula: 38939-88-7

The Article related to vinylbenzotriazole arylbenzotriazole oxide preparation, hydroxybenzotriazole alkenylboronic arylboronic acid coupling copper catalyst, Heterocyclic Compounds (More Than One Hetero Atom): Other 5-Membered Rings, Two Or More Hetero Atoms and other aspects.HPLC of Formula: 38939-88-7

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Milicevic Sephton, Selena; Vetterli, Peter T.; Pedani, Valentina; Cermak, Stjepko; Chiotellis, Aristeidis; Roscales, Sylvia; Mueller Herde, Adrienne; Schibli, Roger; Auberson, Yves P.; Ametamey, Simon M. published an article in 2017, the title of the article was Synthesis and Biological Evaluation of Quinoxaline Derivatives for PET Imaging of the NMDA Receptor.Recommanded Product: 2-Chloro-4-methyl-1-nitrobenzene And the article contains the following content:

Due to the biol. complexity of the N-methyl-D-aspartate receptor (NMDAR), the development of a positron emission tomog. radiotracer for the imaging of NMDAR has met with limited success. Recent studies have established the presence of GluN2A subunit of the NMDAR in the heart and its role in the regulation of intracellular calcium levels. In our efforts to develop an imaging agent for the GluN2A subunit, we designed three new compounds based on a quinoxaline scaffold. The synthesis of the analogs was based on a two-step Kabachnik-Fields reaction in sequence with Suzuki cross-coupling and acid hydrolysis. They exhibited comparable high binding affinity values below 5 nM. A two-step radiolabeling procedure was successfully developed for the synthesis of [18F]I. [18F]I was obtained in a modest overall radiochem. yield of 5.5 ± 4.2%, a good specific radioactivity of 254 ± 158 GBq/μmol, and a radiochem. purity > 99%. While two compounds showed comparable binding affinity towards NMDAR, sluggish radiolabeling, prevented their further evaluation. For [18F]I, in vitro autoradiog. on rat heart slices demonstrated heterogeneous but unspecific accumulation, whereas for the brain a high in vitro specificity towards NMDAR, could be demonstrated. The experimental process involved the reaction of 2-Chloro-4-methyl-1-nitrobenzene(cas: 38939-88-7).Recommanded Product: 2-Chloro-4-methyl-1-nitrobenzene

The Article related to quinoxaline preparation pet imaging, Heterocyclic Compounds (More Than One Hetero Atom): Pyrazines and Quinoxalines (Including Piperazines) and other aspects.Recommanded Product: 2-Chloro-4-methyl-1-nitrobenzene

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On September 11, 2009, Botton, Gerard; Valeur, Eric; Kergoat, Micheline; Charon, Christine; Elbawab, Samer published a patent.SDS of cas: 38939-88-7 The title of the patent was Preparation of quinoxalinone derivatives as insulin secretion stimulators useful for the treatment of diabetes. And the patent contained the following:

The title compounds I [R1 = H, alkyl, cycloalkyl, aryl, etc.; R6 = alkyl, aryl, heteroaryl, etc.; R2-R5 = H, Y or Z; Y = alkyl, cycloalkyl, heterocycloalkyl, etc.; Z = OH, SH, halo, CN. etc.], useful as insulin secretion stimulators for the prophylaxis and/or treatment of diabetes and pathologies associated, were prepared E.g., a multi-step synthesis of II, starting from 2-chloronitrobenzene and 2,2-difluoroethylamine, was given. Exemplified compounds I were evaluated in pancreatic INS-1 cells for their superior response to glucose (data given for representative compounds I). Pharmacetical composition comprising I is disclosed. The experimental process involved the reaction of 2-Chloro-4-methyl-1-nitrobenzene(cas: 38939-88-7).SDS of cas: 38939-88-7

The Article related to quinoxalinone preparation insulin secretion stimulator antidiabetic, Heterocyclic Compounds (More Than One Hetero Atom): Pyrazines and Quinoxalines (Including Piperazines) and other aspects.SDS of cas: 38939-88-7

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On September 30, 1994, Jonquieres, A.; Roizard, D.; Lochon, P. published an article.Electric Literature of 38939-88-7 The title of the article was Synthesis of a new styrene monomer: the 3-chloro-4-nitrostyrene. Free radical polymerization reactivity compared to 4-chloro-3-nitrostyrene. And the article contained the following:

A satisfactory synthesis route to a new monomer, the 3-chloro-4-nitrostyrene (3-CNS) is described. The results of free radical polymerization experiments (limit of conversion, global kinetics) are reported by comparison with those of the isomer 4-chloro-3-nitrostyrene (4-CNS). They show the great influence of the nitro group position which markedly increases the reactivity of 3-CNS. The experimental process involved the reaction of 2-Chloro-4-methyl-1-nitrobenzene(cas: 38939-88-7).Electric Literature of 38939-88-7

The Article related to chloro nitro styrene synthesis polymerization, kinetics radical polymerization chloronitrostyrene, Chemistry of Synthetic High Polymers: Polymerization Kinetics, Mechanisms, Thermodynamics, Catalysis, Catalysts and other aspects.Electric Literature of 38939-88-7

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Dai, Liyan; Yu, Jie; Chen, Yingqi; Yu, Shichao published an article in 2011, the title of the article was Facile, environmentally friendly synthesis of benzaldehyde and phenylacetaldehyde analogs from readily available toluene derivatives.Name: 2-Chloro-4-methyl-1-nitrobenzene And the article contains the following content:

A facile environmentally friendly synthesis of benzaldehydes and phenylacetaldehydes from readily available styrylamines was described. Oxidation of styrylamines by H2O2 afforded benzaldehydes in moderate yields, while hydrolysis of styrylamines afforded phenylacetaldehydes in good yields. The experimental process involved the reaction of 2-Chloro-4-methyl-1-nitrobenzene(cas: 38939-88-7).Name: 2-Chloro-4-methyl-1-nitrobenzene

The Article related to styrylamine oxidation hydrolysis, aminostyrene oxidation hydrolysis, benzaldehyde green preparation, phenylacetaldehyde green preparation, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Aldehydes and Derivatives, Including Sulfur Analogs and other aspects.Name: 2-Chloro-4-methyl-1-nitrobenzene

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On September 25, 1992, Tsuji, Kiyoshi; Nakamura, Katsuya; Konishi, Nobukiyo; Okumura, Hiroyuki; Matsuo, Masaaki published an article.SDS of cas: 38939-88-7 The title of the article was Studies on antiinflammatory agents. I. Synthesis and pharmacological properties of 2′-phenoxymethanesulfonanilide derivatives. And the article contained the following:

Various 2′-phenoxymethanesulfonanilide derivatives I (R1 = H, NO2, CF3, CONH2, SEt, cyano, etc., R2 = H, COMe, Me) and II (R3-R5 = H, 2-F, 2,3-Cl2, 2-Br, 2-OMe, 2-SMe, etc.) were synthesized and evaluated for antiinflammatory and analgesic activities. Thus, 3-(2,4-difluorophenoxy)-4-nitrobenzonitrile reacted with Fe/NH4Cl/EtOH and MeSO2Cl/pyridine to give I (R1 = cyano, R2 = H). Some compounds bearing an electron-attracting substituent at the 4′-position strongly inhibited adjuvant-induced arthritis in rats and acetic acid-induced writhing syndrome in mice without causing gastro-intestinal irritation. Among them, 4′-cyano-(FK867) and 4′-acetyl-(FK3311) 2′-(2,4-difluorophenoxy)methanesulfonanilides were selected as the candidates for further development. The experimental process involved the reaction of 2-Chloro-4-methyl-1-nitrobenzene(cas: 38939-88-7).SDS of cas: 38939-88-7

The Article related to phenoxymethanesulfonanilide preparation analgesic antiinflammatory, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Sulfenic, Sulfinic, and Sulfonic Acids and Derivatives and other aspects.SDS of cas: 38939-88-7

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics