Category: 349-88-2

Organic chlorides are organic molecules with a C-Cl bond, for example chloroform (CH3-Cl) or vinyl chloride(C2H3Cl). 349-88-2, formula is C6H4ClFO2S, Name is 4-Fluorobenzene-1-sulfonyl chloride. Organic chlorides can be used in production of: PVC, Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. Reference of 349-88-2.

Che, Zhiping;Li, Yuanhao;Guo, Xiaolong;He, Jiaxuan;Zhang, Song;Zhu, Lina;Liu, Yibo;Wei, Ruxue;Yang, Yingjun;Huang, Xiaobo;Liu, Shengming;Chen, Genqiang;Tian, Yuee research published 《 Synthesis and Anti-Oomycete Activity of Sulfonate Derivatives of Fenjuntong》, the research content is summarized as follows. In order to discover highly active fungicides, sixteen novel sulfonate derivatives of Fenjuntong were synthesized by structural modification of 2′-hydroxybutyrophenone, and their anti-oomycete activity against Phytophthora capsici Leonian was determined in this study. Among all tested compounds, compound I displayed more significant anti-oomycete activity than the precursor Fenjuntong against P. capsici, and the EC₅₀ values of I and Fenjuntong were 84.50 and 517.25 mg/L, resp. By comparing the anti-oomycete activity of compounds the following conclusions were drawn: (1) Hydroxy group is well tolerated, and sulfonylation of hydroxy group enhances its anti-oomycete activity. (2) The proper length of the ketone carbonyl chain is very important for their anti-oomycete activity. (3) The presence of a site methoxy group in the structural skeleton is closely related to the anti-oomycete activity. These important results will pave the way for further modification of Fenjuntong to develop potential new fungicides.

Reference of 349-88-2, 4-Fluorobenzenesulfonyl chloride is a useful research compound. Its molecular formula is C6H4ClFO2S and its molecular weight is 194.61 g/mol. The purity is usually 95%.

4-Fluorobenzenesulfonyl Chloride is found to be an excellent activating agent for the covalent attachment of biological substances to a variety of solid supports e.g. Sepharose beads. 4-Fluorobenzenesulfonyl Chloride is also used as a reagent for the studies of proteins by fluorine NMR.

4-Fluorobenzenesulfonyl chloride is a reactive chemical that has been shown to have a low safety profile in humans. It is used in the synthesis of replication inhibitors, which are potential anticancer drugs. It also has been shown to inhibit tumor metastasis and growth in mice by binding to the active site of DNA polymerase and inhibiting DNA replication. 4-Fluorobenzenesulfonyl chloride is stable in human liver cells and has been shown to be an effective macroinitiator for proton-coupled electron transfer reactions. This compound has been shown to induce locomotor activity and energy efficiency in rats, which may be due to its ability to increase the number of mitochondria per cell., 349-88-2.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Chlorinated organic compounds are found in nearly every class of biomolecules. 349-88-2, formula is C6H4ClFO2S, Name is 4-Fluorobenzene-1-sulfonyl chloride. Alkyl chlorides, as versatile building blocks in organic chemistry, are used in the preparation of alcohols, thioethers, alkenes, alkynes, esters, and Grignard reagents. Recommanded Product: 4-Fluorobenzene-1-sulfonyl chloride.

Chazin, Eliza L.;Martins, Leonardo B.;de Souz, Marcus Vinicius N.;Gomes, Claudia Regina B.;da Silva, Ana Claudia R.;Branco, Marcelly C.;Sanchez, Eladio F.;Fuly, Andre L.;Vasconcelos, Thatyana R. A. research published 《 Synthesis and biological evaluation of novel 1,3-benzoxathiol-2-one sulfonamides against toxic activities of the venom of Bothrops jararaca and Bothrops jararacussu snakes》, the research content is summarized as follows. The synthesis of new 1,3-benzoxathiol-2-one sulfonamides I = [R = Me, Cl, NO₂, etc.] and evaluation of their ability to inhibit some in vitro (coagulant, proteolytic and hemolytic) and in vivo (hemorrhagic, edematogenic and lethality) toxic activities of Bothrops jararaca and Bothrops jararacussu venoms. Compounds I was synthesized from the coupling of intermediate 5-amino-6-methoxybenzo[d][1,3]oxathiol-2-one with benzenesulfonyl chlorides. Characterization of the products was achieved by NMR and electrospray ionization mass spectra (ESI-MS) techniques. Biol. assay results had shown that most of compounds inhibited the main toxic activities of the venom of the two snake species. Compound I = [R = O₂N] was the most efficient in inhibiting hemolysis of B. jararaca, and coagulation and proteolysis induced by both venoms. For in vivo activities, all compounds inhibited the edema, from 35 to 72%, and most of them exhibited antihemorrhagic and antilethality activities. Thus, the results pointed to the biol. potential of these compounds, being promising mols. to treat envenomation by these snakes as well as to aid the current antivenom serum therapy.

Recommanded Product: 4-Fluorobenzene-1-sulfonyl chloride, 4-Fluorobenzenesulfonyl chloride is a useful research compound. Its molecular formula is C6H4ClFO2S and its molecular weight is 194.61 g/mol. The purity is usually 95%.

4-Fluorobenzenesulfonyl Chloride is found to be an excellent activating agent for the covalent attachment of biological substances to a variety of solid supports e.g. Sepharose beads. 4-Fluorobenzenesulfonyl Chloride is also used as a reagent for the studies of proteins by fluorine NMR.

4-Fluorobenzenesulfonyl chloride is a reactive chemical that has been shown to have a low safety profile in humans. It is used in the synthesis of replication inhibitors, which are potential anticancer drugs. It also has been shown to inhibit tumor metastasis and growth in mice by binding to the active site of DNA polymerase and inhibiting DNA replication. 4-Fluorobenzenesulfonyl chloride is stable in human liver cells and has been shown to be an effective macroinitiator for proton-coupled electron transfer reactions. This compound has been shown to induce locomotor activity and energy efficiency in rats, which may be due to its ability to increase the number of mitochondria per cell., 349-88-2.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

The class of organic compounds having covalently a bonded chlorine atom is called organic chlorides. 349-88-2, formula is C6H4ClFO2S, Name is 4-Fluorobenzene-1-sulfonyl chloride. Their wide structural variety and divergent chemical properties lead to a broad range of named reactions and applications. COA of Formula: C6H4ClFO2S.

Cellnik, Torsten;Healy, Alan R. research published 《 Sulfonyl Chlorides as Thiol Surrogates for Carbon-Sulfur Bond Formation: One-Pot Synthesis of Thioethers and Thioesters》, the research content is summarized as follows. A method to synthesize thioethers and thioesters directly from readily available sulfonyl chlorides was reported. A transient intermediate formed during phosphine-mediated deoxygenation of sulfonyl chlorides was trapped in situ by activated alcs. or carboxylic acids to effect carbon-sulfur bond formation. The method is operationally simple and tolerates a broad range of functional groups. Special attention was focused on the late-stage diversification of densely functionalized natural products and pharmaceuticals.

349-88-2, 4-Fluorobenzenesulfonyl chloride is a useful research compound. Its molecular formula is C6H4ClFO2S and its molecular weight is 194.61 g/mol. The purity is usually 95%.

4-Fluorobenzenesulfonyl Chloride is found to be an excellent activating agent for the covalent attachment of biological substances to a variety of solid supports e.g. Sepharose beads. 4-Fluorobenzenesulfonyl Chloride is also used as a reagent for the studies of proteins by fluorine NMR.

4-Fluorobenzenesulfonyl chloride is a reactive chemical that has been shown to have a low safety profile in humans. It is used in the synthesis of replication inhibitors, which are potential anticancer drugs. It also has been shown to inhibit tumor metastasis and growth in mice by binding to the active site of DNA polymerase and inhibiting DNA replication. 4-Fluorobenzenesulfonyl chloride is stable in human liver cells and has been shown to be an effective macroinitiator for proton-coupled electron transfer reactions. This compound has been shown to induce locomotor activity and energy efficiency in rats, which may be due to its ability to increase the number of mitochondria per cell., COA of Formula: C6H4ClFO2S

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Chloride substituents modify the physical properties of organic compounds in several ways. 349-88-2, formula is C6H4ClFO2S, Name is 4-Fluorobenzene-1-sulfonyl chloride. They are typically denser than water due to the presence of chlorine, which has a high atomic weight. Electric Literature of 349-88-2.

Cao, Yunpeng;Wang, Xinmou;Jiao, Haoran;Song, Hongjian;Liu, Yuxiu;Wang, Qingmin research published 《 Visible-light-induced Smiles rearrangement without release of SO₂: rapid access to alkyl sulfonyl derivatives》, the research content is summarized as follows. Conventional visible-light-induced Smiles rearrangements generate C, N, or O radicals and release SO₂. Herein, we describe a perfectly atom-economical protocol for Smiles rearrangements without release of SO₂. The protocol not only afforded alkyl sulfinic acid salts via photocatalyzed radical addition, aryl migration, and sulfone radical reduction but also permitted efficient functionalization of butenyl heteroaryl sulfone derivatives under mild conditions.

349-88-2, 4-Fluorobenzenesulfonyl chloride is a useful research compound. Its molecular formula is C6H4ClFO2S and its molecular weight is 194.61 g/mol. The purity is usually 95%.

4-Fluorobenzenesulfonyl Chloride is found to be an excellent activating agent for the covalent attachment of biological substances to a variety of solid supports e.g. Sepharose beads. 4-Fluorobenzenesulfonyl Chloride is also used as a reagent for the studies of proteins by fluorine NMR.

4-Fluorobenzenesulfonyl chloride is a reactive chemical that has been shown to have a low safety profile in humans. It is used in the synthesis of replication inhibitors, which are potential anticancer drugs. It also has been shown to inhibit tumor metastasis and growth in mice by binding to the active site of DNA polymerase and inhibiting DNA replication. 4-Fluorobenzenesulfonyl chloride is stable in human liver cells and has been shown to be an effective macroinitiator for proton-coupled electron transfer reactions. This compound has been shown to induce locomotor activity and energy efficiency in rats, which may be due to its ability to increase the number of mitochondria per cell., Electric Literature of 349-88-2

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. 349-88-2, formula is C6H4ClFO2S, Name is 4-Fluorobenzene-1-sulfonyl chloride. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. HPLC of Formula: 349-88-2.

Baker, Rachel J.;Ching, Justin;Hou, Teh Ren;Franzoni, Ivan;Lautens, Mark research published 《 Dearomative Cyclopropanation of Naphthols via Cyclopropene Ring-Opening》, the research content is summarized as follows. The dearomatization of 2-naphthols represents a simple method for the construction of complex 3D structures from simple planar starting materials. A cyclopropanation of 2-naphthols that proceeds via cyclopropene ring-opening using rhodium and acid catalysis under mild conditions is described. The vinyl cyclopropane mols. were formed with high chemoselectivity and scalability, which could be further functionalized at different sites. Both computational and exptl. evidence were used to elucidate the reaction mechanism.

HPLC of Formula: 349-88-2, 4-Fluorobenzenesulfonyl chloride is a useful research compound. Its molecular formula is C6H4ClFO2S and its molecular weight is 194.61 g/mol. The purity is usually 95%.

4-Fluorobenzenesulfonyl Chloride is found to be an excellent activating agent for the covalent attachment of biological substances to a variety of solid supports e.g. Sepharose beads. 4-Fluorobenzenesulfonyl Chloride is also used as a reagent for the studies of proteins by fluorine NMR.

4-Fluorobenzenesulfonyl chloride is a reactive chemical that has been shown to have a low safety profile in humans. It is used in the synthesis of replication inhibitors, which are potential anticancer drugs. It also has been shown to inhibit tumor metastasis and growth in mice by binding to the active site of DNA polymerase and inhibiting DNA replication. 4-Fluorobenzenesulfonyl chloride is stable in human liver cells and has been shown to be an effective macroinitiator for proton-coupled electron transfer reactions. This compound has been shown to induce locomotor activity and energy efficiency in rats, which may be due to its ability to increase the number of mitochondria per cell., 349-88-2.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Organic chlorides are organic molecules with a C-Cl bond, for example chloroform (CH3-Cl) or vinyl chloride(C2H3Cl). 349-88-2, formula is C6H4ClFO2S, Name is 4-Fluorobenzene-1-sulfonyl chloride. Organic chlorides can be used in production of: PVC, Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. Safety of 4-Fluorobenzene-1-sulfonyl chloride.

Babu, Sakamuri Sarath;Gopinath, Purushothaman research published 《 Photomediated Tandem Sulfonyl Addition-Chemoselective N-Cyclization of o-Alkenyl Aryl Ureas: Direct Assembly of Functionalized Dihydroquinazolinones》, the research content is summarized as follows. Photoredox-mediated tandem addition-chemoselective cyclization of o-alkenyl aryl ureas was reported for the synthesis of sulfonyl and activated alkyl-decorated dihydroquinazolinones I [R = Et, Bn, 4-MeC₆H₄, etc.; R¹ = Et, Bn, CH₂-4-MeOC₆H₄; R² = CH₂CN, SO₂Et, SO₂-4-MeC₆H₄, etc.]. By a careful choice of o-alkenyl aryl urea starting materials, chemoselective N-cyclization in the presence of more reactive amidic oxygen was achieved. The scope of the methodol. with a variety of sulfonyl chlorides and activated alkyl halides was discussed. Finally, large-scale synthesis of sulfonyl-substituted dihydroquinazolinone showcased the synthetic utility of the methodol.

Safety of 4-Fluorobenzene-1-sulfonyl chloride, 4-Fluorobenzenesulfonyl chloride is a useful research compound. Its molecular formula is C6H4ClFO2S and its molecular weight is 194.61 g/mol. The purity is usually 95%.

4-Fluorobenzenesulfonyl Chloride is found to be an excellent activating agent for the covalent attachment of biological substances to a variety of solid supports e.g. Sepharose beads. 4-Fluorobenzenesulfonyl Chloride is also used as a reagent for the studies of proteins by fluorine NMR.

4-Fluorobenzenesulfonyl chloride is a reactive chemical that has been shown to have a low safety profile in humans. It is used in the synthesis of replication inhibitors, which are potential anticancer drugs. It also has been shown to inhibit tumor metastasis and growth in mice by binding to the active site of DNA polymerase and inhibiting DNA replication. 4-Fluorobenzenesulfonyl chloride is stable in human liver cells and has been shown to be an effective macroinitiator for proton-coupled electron transfer reactions. This compound has been shown to induce locomotor activity and energy efficiency in rats, which may be due to its ability to increase the number of mitochondria per cell., 349-88-2.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

The class of organic compounds having covalently a bonded chlorine atom is called organic chlorides. 349-88-2, formula is C6H4ClFO2S, Name is 4-Fluorobenzene-1-sulfonyl chloride. Their wide structural variety and divergent chemical properties lead to a broad range of named reactions and applications. Computed Properties of 349-88-2.

Xie, Dandan;Hu, Xin;Ren, Xiaoli;Yang, Zaiping research published 《 Synthesis and bioactivities of novel piperonylic acid derivatives containing a sulfonic acid ester moiety》, the research content is summarized as follows. In order to develop efficient, broad-spectrum and structurally simple agricultural bactericide, the structure of piperonylic acid was modified and a series of novel piperonylic acid derivatives I [R = Ph, 2-naphthyl, benzyl, etc.] containing a sulfonic acid ester moiety was synthesized. Bioassay results indicated the compounds I exhibited significantly antibacterial activities. Among them, compound I [R = phenyl] exhibited excellent antibacterial activities against Pseudomonas syringae pv. Actinidiae (Psa), with inhibitory value 99 and 85% at 100μg/mL and 50μg/mL, resp., which was higher than that of thiodiazole-copper (84 and 77%) and bismerthiazol (96 and 78%). In addition, some compounds also showed moderate insecticidal activity against Spodoptera frugiperda. The above mentioned results confirm the broadening of the application of piperonylic acid, with reliable support for the development of novel agrochem. bactericide.

Computed Properties of 349-88-2, 4-Fluorobenzenesulfonyl chloride is a useful research compound. Its molecular formula is C6H4ClFO2S and its molecular weight is 194.61 g/mol. The purity is usually 95%.

4-Fluorobenzenesulfonyl Chloride is found to be an excellent activating agent for the covalent attachment of biological substances to a variety of solid supports e.g. Sepharose beads. 4-Fluorobenzenesulfonyl Chloride is also used as a reagent for the studies of proteins by fluorine NMR.

4-Fluorobenzenesulfonyl chloride is a reactive chemical that has been shown to have a low safety profile in humans. It is used in the synthesis of replication inhibitors, which are potential anticancer drugs. It also has been shown to inhibit tumor metastasis and growth in mice by binding to the active site of DNA polymerase and inhibiting DNA replication. 4-Fluorobenzenesulfonyl chloride is stable in human liver cells and has been shown to be an effective macroinitiator for proton-coupled electron transfer reactions. This compound has been shown to induce locomotor activity and energy efficiency in rats, which may be due to its ability to increase the number of mitochondria per cell., 349-88-2.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Organic chlorides are organic molecules with a C-Cl bond, for example chloroform (CH3-Cl) or vinyl chloride(C2H3Cl). 349-88-2, formula is C6H4ClFO2S, Name is 4-Fluorobenzene-1-sulfonyl chloride. Organic chlorides can be used in production of: PVC, Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. Category: chlorides-buliding-blocks.

Korkmaz, Adem;Bursal, Ercan research published 《 Benzothiazole sulfonate derivatives bearing azomethine: Synthesis, characterization, enzyme inhibition and molecular docking study》, the research content is summarized as follows. Enzyme inhibition is one of the most applied ways to find new diagnostic facilities for the prevention and treatment of many health problems. For example, tyrosinase and pancreatic lipase inhibition have been used for the treatment of skin pigmentation problems and obesity, resp. This study mainly focused on evaluating inhibition of tyrosinase and pancreatic lipase by newly synthesized sulfonate derivatives I [R = 2,4,6-Me₃C₆H₂, 2-naphthyl, 4-BrC₆H₄, etc.]. The structural characterizations of the compounds were performed by ¹H NMR, ¹³C NMR and HR-MS analyses. According to the in-vitro enzyme inhibition methods, compound I [R = 4-FC₆H₄] had the highest tyrosinase inhibitory activity (46.9 ± 3.6μM IC₅₀ value). On the other hand, effective pancreatic lipase inhibitory activities of I [R = 4-MeOC₆H₄, 4-FC₆H₄, 4-MeC₆H₄] were determined from their low IC₅₀ values 58.3 ± 6.7μM, 59.5 ± 13.8μM and 64.8 ± 6.3μM, resp. Mol. docking studies were also conducted with tyrosinase and pancreatic lipase enzymes sep. Finally, the ADME studies were carried out to determine the pharmacokinetics, drug similarities and medicinal properties of the target compounds

Category: chlorides-buliding-blocks, 4-Fluorobenzenesulfonyl chloride is a useful research compound. Its molecular formula is C6H4ClFO2S and its molecular weight is 194.61 g/mol. The purity is usually 95%.

4-Fluorobenzenesulfonyl Chloride is found to be an excellent activating agent for the covalent attachment of biological substances to a variety of solid supports e.g. Sepharose beads. 4-Fluorobenzenesulfonyl Chloride is also used as a reagent for the studies of proteins by fluorine NMR.

4-Fluorobenzenesulfonyl chloride is a reactive chemical that has been shown to have a low safety profile in humans. It is used in the synthesis of replication inhibitors, which are potential anticancer drugs. It also has been shown to inhibit tumor metastasis and growth in mice by binding to the active site of DNA polymerase and inhibiting DNA replication. 4-Fluorobenzenesulfonyl chloride is stable in human liver cells and has been shown to be an effective macroinitiator for proton-coupled electron transfer reactions. This compound has been shown to induce locomotor activity and energy efficiency in rats, which may be due to its ability to increase the number of mitochondria per cell., 349-88-2.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. 349-88-2, formula is C6H4ClFO2S, Name is 4-Fluorobenzene-1-sulfonyl chloride. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. Category: chlorides-buliding-blocks.

Korkmaz, Adem;Bursal, Ercan research published 《 An in vitro and in silico study on the synthesis and characterization of novel bis(sulfonate) derivatives as tyrosinase and pancreatic lipase inhibitors》, the research content is summarized as follows. Herein, authors present a straightforward synthetic strategy mediated by triethylamine to prepare the target salicylaldehyde functional group’s bearing bis(sulfonate) derivatives The novel bis(sulfonate) derivatives were designed, synthesized, and characterized for the first time. Enzyme inhibition effects and enzyme interactions of compounds were evaluated on tyrosinase and pancreatic lipase enzymes by using in silico and in vitro methods. According to the enzyme assays, compound I had more effective inhibition against the pancreatic lipase enzyme with a lower IC₅₀ value (53.3 ± 2.7μM) than the other compounds On the other hand, two of the newly synthesized compounds (II and I) had effective inhibitions against the tyrosinase enzyme with having (49.5 ± 2.5μM) IC₅₀ values. In addition, mol. docking studies were performed to determine the interactions and binding energy levels of the bis(sulfonate) derivatives with tyrosinase and pancreatic lipase. Also, addnl. ADME studies of the bis(sulfonate) compounds were evaluated.

Category: chlorides-buliding-blocks, 4-Fluorobenzenesulfonyl chloride is a useful research compound. Its molecular formula is C6H4ClFO2S and its molecular weight is 194.61 g/mol. The purity is usually 95%.

4-Fluorobenzenesulfonyl Chloride is found to be an excellent activating agent for the covalent attachment of biological substances to a variety of solid supports e.g. Sepharose beads. 4-Fluorobenzenesulfonyl Chloride is also used as a reagent for the studies of proteins by fluorine NMR.

4-Fluorobenzenesulfonyl chloride is a reactive chemical that has been shown to have a low safety profile in humans. It is used in the synthesis of replication inhibitors, which are potential anticancer drugs. It also has been shown to inhibit tumor metastasis and growth in mice by binding to the active site of DNA polymerase and inhibiting DNA replication. 4-Fluorobenzenesulfonyl chloride is stable in human liver cells and has been shown to be an effective macroinitiator for proton-coupled electron transfer reactions. This compound has been shown to induce locomotor activity and energy efficiency in rats, which may be due to its ability to increase the number of mitochondria per cell., 349-88-2.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics