Category: 2272-40-4

Studies on s-triazines. Part VIII. Preparation of L(+) or (-)-2-arylamino-4,6-di-α-glutarylamino-s-triazines was written by Bhatt, S. B.;Khunt, V. N.;Parikh, A. L.. And the article was included in Chemical Era in 1978.Application In Synthesis of 4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine The following contents are mentioned in the article:

The title compounds I [R = R¹C₆H₄ (R¹ = H, o-Me, m-Me, p-Me, o-MeO, m-MeO, p-MeO, o-NO₂, m-NO₂, m-Cl, p-Cl), α-naphthyl] were prepared by treating RNH₂ with cyanuric chloride and treating the resulting s-triazines II with L-glutamic acid. The change in optical activity of I in 0.25N NaOH was of the order o > m > p, whereas this order was p > o > m for I in pyridine. This study involved multiple reactions and reactants, such as 4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine (cas: 2272-40-4Application In Synthesis of 4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine).

4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine (cas: 2272-40-4) belongs to organic chlorides. Organochlorines stimulate the central nervous system and cause convulsions, tremor, nausea, and mental confusion. Examples are dichlorodiphenyltrichloroethane (DDT), chlordane, lindane, endosulfan, and dieldrin. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.Application In Synthesis of 4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Discovery of novel cannabinoid receptor ligands by a virtual screening approach: Further development of 2,4,6-trisubstituted 1,3,5-triazines as CB2 agonists was written by Yrjola, Sari;Kalliokoski, Tuomo;Laitinen, Tuomo;Poso, Antti;Parkkari, Teija;Nevalainen, Tapio. And the article was included in European Journal of Pharmaceutical Sciences in 2013.Synthetic Route of C9H6Cl2N4 The following contents are mentioned in the article:

3D ligand-based virtual screening was employed to identify novel scaffolds for cannabinoid receptor ligand development. A total of 112 compounds with diverse structures were purchased from com. vendors. 12 CB1 receptor antagonists/inverse agonists and 10 CB2 receptor agonists were identified in vitro. One of the CB2 agonists, N-cyclopentyl-4-ethoxy-6-(4-methylpiperidin-1-yl)-1,3,5-triazin-2-amine (19, -log EC₅₀ = 7.5, E_max = 255%) was selected for further development. As far as we are aware, the compound’s 1,3,5-triazine scaffold represents a new core structure for CB2 agonists. A library of fifty-seven 2,4,6-trisubstituted-1,3,5-triazines was created to clarify the structure-activity relationship study of the analogs. This study involved multiple reactions and reactants, such as 4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine (cas: 2272-40-4Synthetic Route of C9H6Cl2N4).

4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine (cas: 2272-40-4) belongs to organic chlorides. An organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.Synthetic Route of C9H6Cl2N4

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Synthesis and studies of some novel s-triazine based aminopyrimidines, isoxazoles and 1,5-benzothiazepines was written by Solankee, Anjani;Kapadia, Kishor;Solankee, Pankit;Prajapati, Yogesh;Patel, Hiral;Solankee, Sejal. And the article was included in Indian Journal of Chemistry in 2007.SDS of cas: 2272-40-4 The following contents are mentioned in the article:

Elegant syntheses of aminopyrimidines I (R = H, 2-Cl, 3-Cl, 2-NO₂, 2-MeO), isoxazoles II, and 1,5-benzothiazepines III are presented starting from chalcones IV based on the s-triazine nucleus. These chalcones IV, on cyclization with guanidine nitrate or hydroxylamine hydrochloride in the presence of alkali give I and II, resp. Further IV, on cyclization with 2-aminothiophenol in the presence of few drops of glacial acetic acid give III. All the products obtained from these reactions are characterized by elemental anal., IR, ¹H NMR and mass spectral data. This study involved multiple reactions and reactants, such as 4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine (cas: 2272-40-4SDS of cas: 2272-40-4).

4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine (cas: 2272-40-4) belongs to organic chlorides. Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. The hydrocarbon processing industry (HPI) and others are affected by damage caused by these substances.While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.SDS of cas: 2272-40-4

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Coloration of fibrin fabric with berberine natural dye with ultrasonic technique using ZnO nano powder as light fastness improving was written by Kamel, M. M.;Mashaly, Hamada M.. And the article was included in World Applied Sciences Journal in 2013.Category: chlorides-buliding-blocks The following contents are mentioned in the article:

Berberine, a natural cationic colorant, is the major component of Amur Cork tree extract was used as a natural basic dye since the synthetic basic dyes remarked high acute and chronic toxicity on human beings, carcinogenic effect on animals, in addition to a hazardous effect on aquatic marines. These factors brightened the scope to carry out this research, by making a comparative dyeing study by ultrasonic and conventional heating techniques on anionized fibrin fabrics with the berberine dye. It is found that the performance of ZnO nano particles as UV-absorbers can be efficiently transferred to fabric materials. The UV tests indicate a significant improvement in the UV absorbing activity in the ZnO-treated fabrics. This study involved multiple reactions and reactants, such as 4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine (cas: 2272-40-4Category: chlorides-buliding-blocks).

4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine (cas: 2272-40-4) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.Category: chlorides-buliding-blocks

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Development of s-triazine anticytokinins and their quantitative structure-activity relationship was written by Shimizu, Ryo;Iwamura, Hajime;Matsubara, Satoshi;Fujita, Toshio. And the article was included in Journal of Agricultural and Food Chemistry in 1989.Electric Literature of C9H6Cl2N4 The following contents are mentioned in the article:

A new, nonadenylate series of anticytokinins, N²-substituted 2-amino-4-chloro-6-(ethylamino)-s-triazines, has been developed. The activity in terms of the I₅₀ value of the most potent members was (0.3-0.5) × 10^-6M when examined by the tobacco (Nicotiana tabacum) callus assay in the presence of 0.05 × 10^-6 M kinetin. The design of the mol. was made on the basis of insight into the active structure obtained from a cytokinin receptor map drawn previously. Quant. anal. of their structure-activity relationship showed that the mode of their binding to the receptor was in important ways the same as for previously known anticytokinins, the structure of which resembles the adenylate cytokinins. This study involved multiple reactions and reactants, such as 4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine (cas: 2272-40-4Electric Literature of C9H6Cl2N4).

4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine (cas: 2272-40-4) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control.Electric Literature of C9H6Cl2N4

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Design and characterization of some new non-symmetric substituted triazines and triazine derivatives was written by Thakare, S. S.;Dhote, S. N.. And the article was included in International Journal of Pharmaceutical Sciences and Research in 2020.Category: chlorides-buliding-blocks The following contents are mentioned in the article:

Attempts were made to carry out the laboratory synthesis of non-sym. mono-, di- and tri- substituted 1,3,5-triazines I (R = Et, Ph, 2,5-dimethylphenyl, 4-nitrophenyl, etc.; R¹ = Cl, naphthalen-1-oxy; R² = Cl, benzothiazol-2-ylsulfanyl, phenylsulfanyl) by the action of the electron-donating substituent on 2,4,6-trichloro-1,3,5-triazine by aromatic nucleophilic substitution reaction mechanism (SNAr reaction) by temperature controlled. The introduction of the amino group (-NH-), ether (-O-) and thiol (-S-) Linker Bridge show more promising antibacterial activity. The yield of newly synthesized compounds I was quite well, and their structures were confirmed by using IR, ¹H NMR, and Mass spectral data. This study involved multiple reactions and reactants, such as 4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine (cas: 2272-40-4Category: chlorides-buliding-blocks).

4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine (cas: 2272-40-4) belongs to organic chlorides. Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. The hydrocarbon processing industry (HPI) and others are affected by damage caused by these substances.While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.Category: chlorides-buliding-blocks

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Synthesis 1-[4-[[4,6-bis(phenylamino)-1,3,5-triazin-2-yl]amino]phenyl]-2-propen-1-one and 1-[3-[4-[[4,6-bis(phenylamino)-1,3,5-triazin-2-yl]amino]phenyl]-1H-pyrazol-1-yl]ethanone and 2-amino-6-[4-[[4,6-bis(phenylamino)-1,3,5-triazin-2-yl]amino]phenyl]-3-pyridinecarbonitrile derivatives and determination of their activity as antibacterial agents was written by Kapadia, Kishor;Solankee, Pankit;Prajapati, Yogesh;Patel, Hiral;Solankee, Sejal;Solankee, Anjani. And the article was included in Organic Chemistry: An Indian Journal in 2007.Category: chlorides-buliding-blocks The following contents are mentioned in the article:

A method for the synthesis of the title compounds is reported here. The target compounds thus prepared included 1-[4-[[4,6-bis(phenylamino)-1,3,5-triazin-2-yl]amino]phenyl]-2-propen-1-one derivatives and 1-[3-[4-[[4,6-bis(phenylamino)-1,3,5-triazin-2-yl]amino]phenyl]-1H-pyrazol-1-yl]ethanone derivatives and 2-amino-6-[4-[[4,6-bis(phenylamino)-1,3,5-triazin-2-yl]amino]phenyl]-3-pyridinecarbonitrile derivatives All the synthesized compounds have been screened for their antibacterial activity against Staphylococcus aureus, Bacillus subtilis, Escherichia coli, Salmonella paratyphi-B (Salmonella schottmuelleri). The constitutions of newly synthesized compounds have been established on the basis of their elemental anal., IR and ¹H NMR spectral data. This study involved multiple reactions and reactants, such as 4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine (cas: 2272-40-4Category: chlorides-buliding-blocks).

4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine (cas: 2272-40-4) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. Alkyl chlorides are versatile building blocks in organic chemistry. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available.Category: chlorides-buliding-blocks

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Studies on the biological activity of heterocyclic compounds. Part IV. On the blinding activities and acute oral toxicities of aminobenzenes, pyrimidines, purines, amino-s-triazines and their related compounds in baby chicks was written by Obara, Yoshihiko;Umemoto, Yasunaga;Matsubara, Hiromichi. And the article was included in Nippon Nogei Kagaku Kaishi in 1981.Related Products of 2272-40-4 The following contents are mentioned in the article:

Feeding experiments were carried out on male chicks with 44 title compounds When formoguanamine (I) [504-08-5] and 2-amino-s-triazine (II) [4122-04-7] were given to chicks orally (1% active ingredient), blindness resulted. Introduction of the N-substituted amino group(s) into these 2 compounds did not cause blindness. Phenylenediamines (1% active ingredient) had acute toxicities and aminodichloro-s-triazines (1% active ingredient) the strongest lethal toxicities. 2,4-Bis(diethylamino)- [1898-73-3] and 2-ethylamino-4-isopropylamino-s-triazine  [4150-65-6] (3% active ingredient) caused loss of appetite in baby chicks. This study involved multiple reactions and reactants, such as 4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine (cas: 2272-40-4Related Products of 2272-40-4).

4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine (cas: 2272-40-4) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. Alkyl chlorides readily react with amines to give substituted amines. Alkyl chlorides are substituted by softer halides such as the iodide in the Finkelstein reaction.Related Products of 2272-40-4

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Normal coordinate analysis and fungicidal activity study on anilazine and its related compound using spectroscopic techniques was written by Sheeja Mol, Gilbert Pushpam;Arul Dhas, Deva Dhas;Hubert Joe, Isaac;Balachandran, Sreedharan. And the article was included in Chemical Physics Letters in 2016.Application In Synthesis of 4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine The following contents are mentioned in the article:

The FTIR and FT-Raman spectra of anilazine have been recorded in the range 400-4000 cm^-1 and 50-3500 cm^-1 resp. The optimized geometrical parameters of the compound were calculated using B3LYP method with 6-311G(d,p) basis set. The distribution of the vibrational bands were carried out with the help of normal coordinate anal. (NCA). The ¹H and ¹³C NMR spectra have been recorded and chem. shifts of the mol. were also calculated using the gauge independent AO (GIAO) method. The UV-Visible spectrum of the compound was recorded in the region 190-900 nm and the electronic properties were determined by time-dependent DFT (TD-DFT) approach. Anilazine was screened for its antifungal activity. Mol. docking studies are conducted to predict its fungicidal activity. This study involved multiple reactions and reactants, such as 4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine (cas: 2272-40-4Application In Synthesis of 4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine).

4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine (cas: 2272-40-4) belongs to organic chlorides. An organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control.Application In Synthesis of 4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Synthesis and antitumor evaluation of a novel series of triaminotriazine derivatives was written by Zheng, Mingfang;Xu, Chenghui;Ma, Jianwei;Sun, Yan;Du, Feifei;Liu, Hong;Lin, Liping;Li, Chuan;Ding, Jian;Chen, Kaixian;Jiang, Hualiang. And the article was included in Bioorganic & Medicinal Chemistry in 2007.HPLC of Formula: 2272-40-4 The following contents are mentioned in the article:

A series of triaminotriazine derivatives (compounds 5a-f, 6a-x, and 7a-g) was designed, synthesized, and evaluated for their inhibition activities to colorectal cancer (CRC) cell lines (HCT-116 and HT-29). Most of the synthesized compounds demonstrated moderate anti-proliferatory effects on both HCT-116 and HT-29 cell lines at the concentration of 10 μM. The inhibitory activities against HCT-116 and HT-29 cell lines were discussed to develop the structure-activity relationships of this new series. Compounds 6l (I) and 6o exhibited prominent inhibition activities toward HCT-116, with IC₅₀s of 0.76 and 0.92 μM, resp. The in vivo antitumor studies and pharmacokinetics of compound 6l showed that it might be a promising new hit for further development of antitumor agents. This study involved multiple reactions and reactants, such as 4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine (cas: 2272-40-4HPLC of Formula: 2272-40-4).

4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine (cas: 2272-40-4) belongs to organic chlorides. Organochlorines are organic compounds having multiple chlorine atoms. They were the first synthetic pesticides that were used in agriculture. They are resistant to most microbial and chemical degradations. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control.HPLC of Formula: 2272-40-4

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics