Category: 219537-97-0

Yu, Chuanming published the artcilePhotochromic dithienylethene based on porphyrin for a nondestructive information processing, HPLC of Formula: 219537-97-0, the publication is Journal of Porphyrins and Phthalocyanines (2018), 22(6), 475-480, database is CAplus.

A 1-[2-methyl-5-((4-tetraphenylporphyrinphenyl)-3-thienyl)-2-[2-methyl-3-thienyl]]cyclopentene combined by 3,3′-(1-cyclopentene-1,2-diyl)bis(5-chloro-2-methyl)thiophene and tetraphenylporphyrin can transform between the open isomer and the closed isomer upon the irradiation of UV or visible light. Thus they can be utilized to write binary data. Furthermore, the open form can emit luminescence but the closed cannot while irradiated by another light that cannot cause optical chem. reactions. Therefore, data can be read out without damage.

Journal of Porphyrins and Phthalocyanines published new progress about 219537-97-0. 219537-97-0 belongs to chlorides-buliding-blocks, auxiliary class Fused/Partially Saturated Cycles,Cyclopentenes, name is 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene, and the molecular formula is C6H5NO, HPLC of Formula: 219537-97-0.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Chen, Kuang-Yen published the artcileTetrapodal Molecular Switches and Motors: Synthesis and Photochemistry, Application In Synthesis of 219537-97-0, the publication is Journal of Organic Chemistry (2014), 79(15), 7032-7040, database is CAplus and MEDLINE.

The design, synthesis, and dynamic behavior of a series of novel tetrapodal mol. switches and motors containing common functional groups for attachment to various inorganic and organic surfaces are presented. Using a Diels-Alder reaction, an anthracene unit with four functionalized alkyl substituents (“legs”) was coupled to maleimide-functionalized mol. switches or motors under ambient conditions. Terminal functional groups at the “legs” include thioacetates and azides, making these switches and motors ideal candidates for attachment to metallic or alkyne-functionalized surfaces. UV/vis absorption spectroscopy shows that the mol. switches and motors retain their ability to undergo reversible photoinduced and/or thermally induced structural changes after attachment to the tetrapodal anthracene.

Journal of Organic Chemistry published new progress about 219537-97-0. 219537-97-0 belongs to chlorides-buliding-blocks, auxiliary class Fused/Partially Saturated Cycles,Cyclopentenes, name is 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene, and the molecular formula is C15H14Cl2S2, Application In Synthesis of 219537-97-0.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Chen, Xinyu published the artcileAcetylcholinesterase Inhibitors with Photoswitchable Inhibition of β-Amyloid Aggregation, Computed Properties of 219537-97-0, the publication is ACS Chemical Neuroscience (2014), 5(5), 377-389, database is CAplus and MEDLINE.

Photochromic cholinesterase inhibitors were obtained from cis-1,2-α-dithienylethene-based compounds by incorporating one or two aminopolymethylene tacrine groups. All target compounds are potent acetyl- (AChE) and butyrylcholinesterase (BChE) inhibitors in the nanomolar concentration range. Compound I bearing an octylene linker exhibited interactions with both the catalytic active site (CAS) and the peripheral anionic site (PAS) of AChE. Yet upon irradiation with light, the mechanism of interaction varied from one photochromic form to another, which was investigated by kinetic studies and proved “photoswitchable”. The AChE-induced β-amyloid (Aβ) aggregation assay gave further exptl. support to this finding: Aβ_1-40 aggregation catalyzed by the PAS of AChE might be inhibited by compound I in a concentration-dependent manner and seems to occur only with one photochromic form. Computational docking studies provided potential binding modes of the compound Docking studies and mol. dynamics (MD) simulations for the ring-open and -closed form indicate a difference in binding. Although both forms can interact with the PAS, more stable interactions are observed for the ring-open form based upon stabilization of a water mol. network within the enzyme, whereas the ring-closed form lacks the required conformational flexibility for an analogous binding mode. The photoswitchable inhibitor identified might serve as valuable mol. tool to investigate the different biol. properties of AChE as well as its role in pathogenesis of AD in in vitro assays.

ACS Chemical Neuroscience published new progress about 219537-97-0. 219537-97-0 belongs to chlorides-buliding-blocks, auxiliary class Fused/Partially Saturated Cycles,Cyclopentenes, name is 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene, and the molecular formula is C15H14Cl2S2, Computed Properties of 219537-97-0.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Xu, Li published the artcileA highly selective and sensitive photoswitchable fluorescent probe for Hg²⁺ based on bisthienylethene-rhodamine 6G dyad and for live cells imaging, Synthetic Route of 219537-97-0, the publication is Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy (2014), 567-574, database is CAplus and MEDLINE.

A new photochromic diarylethene derivative bearing rhodamine 6G dimmer as a fluorescent mol. probe is designed and synthesized successfully. All the compounds are characterized by NMR and mass spectrometry. The bisthienylethene-rhodamine 6G dyad exhibit excellent phtochromism with reversibly color and fluorescence changes alternating irradiation with UV and visible light. Upon addition of Hg²⁺, its color changes from colorless to red and its fluorescence is remarkably enhanced. Whereas other ions including K⁺, Na⁺, Ca²⁺, Mg²⁺, Fe²⁺, Co²⁺, Ni²⁺, Cu²⁺, Zn²⁺, Mn²⁺, Pb²⁺, Ni²⁺, Fe³⁺, Al³⁺, Cr³⁺ and so on induce basically no spectral changes, which constitute a highly selective and sensitive photoswitchable fluorescent probe toward Hg²⁺. Furthermore, by means of laser confocal scanning microscopy experiments, it is demonstrated that this probe can be applied for live cell imaging and monitoring Hg²⁺ in living lung cancer cells with satisfying results, which shows its value of potential application in environmental and biol. systems.

Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy published new progress about 219537-97-0. 219537-97-0 belongs to chlorides-buliding-blocks, auxiliary class Fused/Partially Saturated Cycles,Cyclopentenes, name is 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene, and the molecular formula is C18H24N6O6S4, Synthetic Route of 219537-97-0.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Zhang, Zhiwei published the artcileA building-block design for enhanced visible-light switching of diarylethenes, Product Details of C15H14Cl2S2, the publication is Nature Communications (2019), 10(1), 1-9, database is CAplus and MEDLINE.

Current development of light-responsive materials and technologies imposes an urgent demand on visible-light photoswitching on account of its mild excitation with high penetration ability and low photo-toxicity. However, complicated mol. design and laborious synthesis are often required for visible-light photoswitch, especially for diarylethenes. Worse still, a dilemma is encountered as the visible-light excitation of the diarylethene is often achieved at the expense of photochromic performances. To tackle these setbacks, we introduce a building-block design strategy to achieve all-visible-light photochromism with the triplet-sensitization mechanism. The simply designed diarylethene system is constructed by employing a sensitizer building-block with narrow singlet-triplet energy gap (ΔE_ST) to a diarylethene building-block. A significant improvement on the photochromic efficiency is obtained as well as an enhanced photo-fatigue resistance over those under UV irradiation The balance between the visible-light excitation and decent photochromism is thus realized, promoting a guiding principle for the visible-light photochromism.

Nature Communications published new progress about 219537-97-0. 219537-97-0 belongs to chlorides-buliding-blocks, auxiliary class Fused/Partially Saturated Cycles,Cyclopentenes, name is 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene, and the molecular formula is C10H9NO, Product Details of C15H14Cl2S2.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Li, Ziyong published the artcileSynthesis and properties of dithienylethene-functionalized switchable antibacterial agents, Formula: C15H14Cl2S2, the publication is Organic & Biomolecular Chemistry (2018), 16(38), 6988-6997, database is CAplus and MEDLINE.

Photopharmacol. involving azobenzene has offered a viable alternative for combating bacterial resistance. However, the degradation and potential toxicity of azobenzene limit its further study in vivo. Therefore, searching for an appropriate photoswitch for further clin. application is highly desirable. Herein a series of dithienylethene-functionalized switchable antibacterial agents have been designed and prepared by the introduction of the dithienylethene scaffold into fluoroquinolones. And it was found that these switchable antibacterial agents displayed good photochromism and fluorescence switching behaviors upon irradiation with UV/Vis light in DMSO. Surprisingly, methoxy-substituted dithienylethenes 3a and 3b exhibited fluorescence turn-on behavior. Furthermore, it was found that all of the open-isomers showed partial antibacterial activity on E. coli and S. aureus compared with the native drugs. Apart from 2a and 2b, the other switchable antibacterial agents showed a large difference in antibacterial activity on Gram-neg. E. coli between the open and closed forms, in which the antimicrobial activity of the ring-closed isomers for 1b and 3b was 16 times that of the corresponding ring-open isomers. DFT calculations showed that the ring-closed isomers of 1b and 3b presented a rigid “S-type” conformation, which may be conducive to forming more stable complexes with the DNA gyrase of E. coli.

Organic & Biomolecular Chemistry published new progress about 219537-97-0. 219537-97-0 belongs to chlorides-buliding-blocks, auxiliary class Fused/Partially Saturated Cycles,Cyclopentenes, name is 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene, and the molecular formula is C15H14Cl2S2, Formula: C15H14Cl2S2.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Li, Ziyong published the artcileSolvent-dependent and visible light-activated NIR photochromic dithienylethene modified by difluoroboron β-diketonates as fluorescent turn-on pH sensor, Related Products of chlorides-buliding-blocks, the publication is Dyes and Pigments (2019), 339-347, database is CAplus.

The development of near-IR (NIR) photochromic materials, particularly activated by visible light, are of increasing interest for their potential application in photoresponsive optoelectronics and functional bio-materials. Here, a novel D-DTE-A type dithienylethene NDB, which was modified by difluoroboron β-diketonate (BF₂bdk) and dimethylphenylamine (DMPA) moieties, has been developed. It exhibited solvent-dependent photophys. properties before irradiation, and the visible light-triggered NIR photochromic behavior with solvent-dependent features was only observed in Toluene. Moreover, it displayed intense fluorescent turn-on acid-sensing properties in less polar solvent [Toluene, Dichloromethane (DCM) and Et acetate (EA)] through the blockage of photoinduced electron transfer (PET) effect. Specially, NDB with photochromic inactivity in DCM could perform a unique gated photochromism in the presence of TFA/TEA.

Dyes and Pigments published new progress about 219537-97-0. 219537-97-0 belongs to chlorides-buliding-blocks, auxiliary class Fused/Partially Saturated Cycles,Cyclopentenes, name is 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene, and the molecular formula is C15H14Cl2S2, Related Products of chlorides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Li, Yannian published the artcileRationally Designed Axially Chiral Diarylethene Switches with High Helical Twisting Power, Related Products of chlorides-buliding-blocks, the publication is Chemistry – A European Journal (2014), 20(49), 16286-16292, database is CAplus and MEDLINE.

Three rationally designed axially chiral diarylethene switches were synthesized and their application as chiral dopants for phototunable cholesteric liquid crystal devices was investigated. Design of these mols. was based on the combination of photochromic dithienylcyclopentene core with bridged binaphthyl units as chiral precursors. Aromatic groups were introduced to the mols. at 6,6′-positions of binaphthyls through a Suzuki-Miyaura coupling reaction. Their helical twisting powers (HTPs) are significantly higher than those of the known chiral diarylethenes reported as chiral dopants so far. Photocyclization of these mols. upon light irradiation brought out dramatic variation in HTPs between different states. The primary colors, red, green, and blue, were obtained in reflection on light irradiation and with thermal stability. Moreover, a multi-switchable photodisplay was demonstrated using one of these chiral mol. switches.

Chemistry – A European Journal published new progress about 219537-97-0. 219537-97-0 belongs to chlorides-buliding-blocks, auxiliary class Fused/Partially Saturated Cycles,Cyclopentenes, name is 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene, and the molecular formula is C15H14Cl2S2, Related Products of chlorides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Ma, Liangwei published the artcilePhoto-controlled fluorescence on/off switching of a pseudo[3]rotaxane between an AIE-active pillar[5]arene host and a photochromic bithienylethene guest, Synthetic Route of 219537-97-0, the publication is Chemical Communications (Cambridge, United Kingdom) (2018), 54(19), 2405-2408, database is CAplus and MEDLINE.

A fluorescence photo-switch was constructed based on a host-guest pseudo[3]rotaxane between an AIE-active pillar[5]arene host bearing tetra-Ph ethylene moieties and a photo-responsive dithienylethylene guest containing two cyano-triazole branches. Its fluorescence on/off switching could be controlled by the photochromism reaction of the dithienylethylene unit.

Chemical Communications (Cambridge, United Kingdom) published new progress about 219537-97-0. 219537-97-0 belongs to chlorides-buliding-blocks, auxiliary class Fused/Partially Saturated Cycles,Cyclopentenes, name is 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene, and the molecular formula is C15H14Cl2S2, Synthetic Route of 219537-97-0.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Almasi, Miroslav published the artcileA novel approach to achieve molecular switching in solid-state driving by thermal treatment: A photochromic zinc-coordination polymer, SDS of cas: 219537-97-0, the publication is Inorganica Chimica Acta (2020), 119879, database is CAplus.

The mol. switching of complexes based on diarylethenes in a solid-state is their most frequently studied property. This switching becomes possible when the active carbon atoms acquire a suitable interat. separation in the mol. Even if the structural anal. may suggest conditions disfavoring the occurrence of such switching, it may still be enabled by post-synthetic modification of the sample, like dehydration. In the present study, a novel one-dimensional coordination polymer with composition {[Zn(μ₃-HA)(H₂O)₃]·H₂O}_n was prepared and characterized. In its solid state, however, its thiophene rings were arranged in the non-switchable conformation yielding a C···C separation 4.148(6) Å between the active carbon atoms. After fully dehydrating the sample, this interat. separation decreased to 3.814 Å, making it susceptible to photochromism by UV radiation.

Inorganica Chimica Acta published new progress about 219537-97-0. 219537-97-0 belongs to chlorides-buliding-blocks, auxiliary class Fused/Partially Saturated Cycles,Cyclopentenes, name is 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene, and the molecular formula is C15H14Cl2S2, SDS of cas: 219537-97-0.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics