Category: 16629-19-9

《Making Copper Photocatalysis Even More Robust and Economic: Photoredox Catalysis with [CuII(dmp)2Cl]Cl》 was written by Engl, Sebastian; Reiser, Oliver. Application of 16629-19-9 And the article was included in European Journal of Organic Chemistry in 2020. The article conveys some information:

The CuII complex [CuII(dmp)2Cl]Cl (dmp = 2,9-dimethyl-1,10-phenanthroline) is evaluated as an oxidation stable precursor for visible-light-mediated CuI-photoredox catalysis, being efficient and considerable more cost-effective compared to previously established copper(I) photocatalysts. Its performance and efficiency are demonstrated within a broad scope of atom transfer radical addition (ATRA) reactions, allowing the 1,2-difunctionalization of alkenes, as well as for decarboxylative coupling and an Appel reaction. Moreover, the utility of the complex is shown by various gram-scale functionalizations of styrene, thus suggesting [CuII(dmp)2Cl]Cl to be a low-priced alternative precatalyst for processes run on scale. Furthermore, this study provides UV/Vis evidence on the mechanism for the visible light activation of CuII complexes. In addition to this study using Thiophene-2-sulfonyl chloride, there are many other studies that have used Thiophene-2-sulfonyl chloride(cas: 16629-19-9Application of 16629-19-9) was used in this study.

Thiophene-2-sulfonyl chloride(cas: 16629-19-9) is a member of sulfonyl chlorides. Sulfonyl chlorides are reactive sulfonic acid derivatives similar in properties and reactivity to acid chlorides of carboxylates. The sulfonic acid group, however, is a highly hindered molecule, containing a tetrahedral configuration of substituents. Application of 16629-19-9

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

《Ynamide Smiles Rearrangement Triggered by Visible-Light-Mediated Regioselective Ketyl-Ynamide Coupling: Rapid Access to Functionalized Indoles and Isoquinolines》 was published in Journal of the American Chemical Society in 2020. These research results belong to Wang, Ze-Shu; Chen, Yang-Bo; Zhang, Hao-Wen; Sun, Zhou; Zhu, Chunyin; Ye, Long-Wu. Reference of Thiophene-2-sulfonyl chloride The article mentions the following:

Here, a novel and practical radical Smiles rearrangement triggered by photoredox-catalyzed regioselective ketyl-ynamide coupling is reported, which represents the first radical Smiles rearrangement of ynamides. This method enables facile access to a variety of valuable 2-benzhydrylindoles with broad substrate scope in generally good yields under mild reaction conditions. In addition, this chem. can also be extended to the divergent synthesis of versatile 3-benzhydrylisoquinolines through a similar ketyl-ynamide coupling and radical Smiles rearrangement, followed by dehydrogenative oxidation Moreover, such an ynamide Smiles rearrangement initiated by intermol. photoredox catalysis via addition of external radical sources is also achieved. By control experiments, the reaction was shown to proceed via key ketyl radical and α-imino carbon radical intermediates. After reading the article, we found that the author used Thiophene-2-sulfonyl chloride(cas: 16629-19-9Reference of Thiophene-2-sulfonyl chloride)

Thiophene-2-sulfonyl chloride(cas: 16629-19-9) is a member of sulfonyl chlorides. Sulfonyl chlorides are reactive sulfonic acid derivatives similar in properties and reactivity to acid chlorides of carboxylates. The sulfonic acid group, however, is a highly hindered molecule, containing a tetrahedral configuration of substituents. Reference of Thiophene-2-sulfonyl chloride

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Name: Thiophene-2-sulfonyl chlorideIn 2021 ,《One-pot synthesis of sulfonylhydrazones from sulfonyl chloride, hydrazine hydrate and vinyl azide in water》 was published in Journal of the Iranian Chemical Society. The article was written by Luo, Mengqiang; Wang, Hai; Ren, Xiaorong; Lu, Ruijuan; Qi, Chenze; Zhang, Yaohong; Shen, Runpu. The article contains the following contents:

A facile and eco-friendly protocol for the synthesis of sulfonylhydrazones I [R = Ph, 4-MeC6H4, 4-FC6H4, 4-ClC6H4, 4-BrC6H4; R1 = Me, Ph, 4-MeOC6H4, etc.] from sulfonyl chlorides, hydrazine hydrate and vinyl azides was developed. The unique advantage of this approach was that desired products could be obtained efficiently in water, which meets the requirements of green chem. and provided good perspectives for the sustainable production of new drug candidate. Also, this reaction proceeded in moderate to good yields with a wide tolerance of functional groups. In the part of experimental materials, we found many familiar compounds, such as Thiophene-2-sulfonyl chloride(cas: 16629-19-9Name: Thiophene-2-sulfonyl chloride)

Thiophene-2-sulfonyl chloride(cas: 16629-19-9) is a member of sulfonyl chlorides. Sulfonyl chlorides are reactive sulfonic acid derivatives similar in properties and reactivity to acid chlorides of carboxylates. The sulfonic acid group, however, is a highly hindered molecule, containing a tetrahedral configuration of substituents. Name: Thiophene-2-sulfonyl chloride

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Tian, Yue-E.; Sun, Di; Han, Xiao-Xiao; Yang, Jin-Ming; Zhang, Song; Feng, Nan-Nan; Zhu, Li-Na; Xu, Zhong-Yuan; Che, Zhi-Ping; Liu, Sheng-Ming; Lin, Xiao-Min; Jiang, Jia; Chen, Gen-Qiang published their research in Journal of Asian Natural Products Research in 2021. The article was titled 《Synthesis, anti-oomycete activity and SAR studies of paeonol derivatives》.Computed Properties of C4H3ClO2S2 The article contains the following contents:

Three series of sulfonate derivatives I [R1 = H, OMe; R2 = H, C(O)Me; R3 = Et, Ph, 4-FC6H4, etc.] of paeonol were synthesized and screened in vitro for their anti-oomycete activity against P. capsici, resp. Among all the compounds I [R1 = OMe; R2 = C(O)Me; R3 = 4-Cl-3-O2NC6H3], displayed the best promising and pronounced anti-oomycete activity against P. capsici than zoxamide, with the EC50 values of 24.51 and 26.87 mg/L, resp. The results showed that acetyl and 4-OMe were two necessary groups. The existence of these two sites was closely related to the anti-oomycete activity. Relatively speaking, hydroxyl group was well tolerated, and the results showed that after modification of hydroxyl group with sulfonyl, the anti-oomycete activity was significantly increased. The results came from multiple reactions, including the reaction of Thiophene-2-sulfonyl chloride(cas: 16629-19-9Computed Properties of C4H3ClO2S2)

Thiophene-2-sulfonyl chloride(cas: 16629-19-9) is a member of sulfonyl chlorides. Sulfonyl chlorides are reactive sulfonic acid derivatives similar in properties and reactivity to acid chlorides of carboxylates. The sulfonic acid group, however, is a highly hindered molecule, containing a tetrahedral configuration of substituents. Computed Properties of C4H3ClO2S2

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

《Synthesis of sulfonate derivatives of maltol and their biological activity against Phytophthora capsici and Bursaphelenchus xylophilus in vitro》 was written by Tian, Yue-E.; Sun, Di; Yang, Jin-Ming; Che, Zhi-Ping; Liu, Sheng-Ming; Lin, Xiao-Min; Jiang, Jia; Chen, Gen-Qiang. Reference of Thiophene-2-sulfonyl chloride And the article was included in Journal of Asian Natural Products Research in 2020. The article conveys some information:

Sixteen sulfonate derivatives of maltol were synthesized and screened in vitro for their anti-oomycete and nematicidal activity against Phytophthora capsici and Bursaphelenchus xylophilus, resp. Among all the compounds, , , and exhibited the most promising and pronounced anti-oomycete activity against P. capsici than zoxamide, and the EC50 values of 25.42, 18.44, 23.69, and 27.99 mg/L, resp.; compounds , , , and exhibited potent nematicidal activity with LC50 values ranging from 1 to 2 mg/L, especially and showed the best promising and pronounced nematicidal activity, with LC50 values of 1.1762 and 1.2384 mg/L, resp. The experimental process involved the reaction of Thiophene-2-sulfonyl chloride(cas: 16629-19-9Reference of Thiophene-2-sulfonyl chloride)

Thiophene-2-sulfonyl chloride(cas: 16629-19-9) is a member of sulfonyl chlorides. Sulfonyl chlorides are reactive sulfonic acid derivatives similar in properties and reactivity to acid chlorides of carboxylates. The sulfonic acid group, however, is a highly hindered molecule, containing a tetrahedral configuration of substituents. Reference of Thiophene-2-sulfonyl chloride

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Thirupataiah, B.; Mounika, Guntipally; Reddy, Gangireddy Sujeevan; Kumar, Jetta Sandeep; Hossain, Kazi Amirul; Medishetti, Raghavender; Samarpita, Snigdha; Rasool, Mahaboobkhan; Mudgal, Jayesh; Mathew, Jessy E.; Shenoy, Gautham G.; Rao, C. Mallikarjuna; Chatti, Kiranam; Parsa, Kishore V. L.; Pal, Manojit published their research in European Journal of Medicinal Chemistry in 2021. The article was titled 《PdCl2-catalyzed synthesis of a new class of isocoumarin derivatives containing aminosulfonyl / aminocarboxamide moiety: First identification of a isocoumarin based PDE4 inhibitor》.Reference of Thiophene-2-sulfonyl chloride The article contains the following contents:

In this effort the non-PDE4 inhibitor isocoumarins were transformed into the promising inhibitors via introducing an aminosulfonyl/aminocarboxamide moiety to the C-3 benzene ring attached to the isocoumarin framework. This new class of isocoumarins were synthesized via a PdCl2-catalyzed construction of the 4-allyl substituted 3-aryl isocoumarin ring I (X = SO2Me, SO2Ph, COPh, etc.; R1 = H, 6-Cl, 7-F) starting from the appropriate 2-alkynyl benzamide derivative Several compounds showed good inhibition of PDE4B in vitro and the SAR indicated superiority of aminosulfonamide moiety over aminocarboxamide in terms of PDE4B inhibition. Two compounds I (X = SO2Ph; R1 = 7-F) and I (X = SO2(thiophen-2-yl); R1 = 7-F) with PDE4B IC50 = 0.43 +/= 0.11 and 0.54 +/= 0.19μM and >/= 2-fold selectivity over PDE4D emerged as initial hits. The participation of aminosulfonamide moiety in PDE4B inhibition and the reason for selectivity though moderate shown by I (X = SO2Ph; R1 = 7-F) and I (X = SO2(thiophen-2-yl); R1 = 7-F) was revealed by the in silico docking studies. In view of potential usefulness of moderately selective PDE4B inhibitors the compound I (X = SO2(thiophen-2-yl); R1 = 7-F) was further evaluated in adjuvant induced arthritic rats. Thus, the isocoumarin I (X = SO2(thiophen-2-yl); R1 = 7-F) emerged as a new, safe and moderately selective PDE4B inhibitor could be useful for inflammatory diseases possibly including COVID-19. In the experimental materials used by the author, we found Thiophene-2-sulfonyl chloride(cas: 16629-19-9Reference of Thiophene-2-sulfonyl chloride)

Thiophene-2-sulfonyl chloride(cas: 16629-19-9) is a member of sulfonyl chlorides. Sulfonyl chlorides are reactive sulfonic acid derivatives similar in properties and reactivity to acid chlorides of carboxylates. The sulfonic acid group, however, is a highly hindered molecule, containing a tetrahedral configuration of substituents. Reference of Thiophene-2-sulfonyl chloride

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

《Synthesis and insecticidal activity of sulfonate derivatives of sesamol against Mythimna separata in vivo》 was written by Che, Zhi-Ping; Yang, Jin-Ming; Shan, Xi-Jie; Tian, Yue-E.; Liu, Sheng-Ming; Lin, Xiao-Min; Jiang, Jia; Hu, Mei; Chen, Gen-Qiang. Reference of Thiophene-2-sulfonyl chloride And the article was included in Journal of Asian Natural Products Research in 2020. The article conveys some information:

A series of sulfonate derivatives of sesamol were synthesized and evaluated for their insecticidal activity against a crop-threatening agricultural pest, the pre-third-instar larvae of Mythimna separata in vivo. Among all the target compounds, compounds , , and exhibited more promising insecticidal activity than sesamol and toosendanin, and the final mortality rates (FMRs) of , , , , and toosendanin were 60.7%/60.7%/67.9%/53.6%/32.1%/50.0%, resp. Especially compound exhibited the most potent insecticidal activity with FMRs of 67.9%. This suggested that a 4-fluorophenylsulfonyl group introduced at the hydroxyl position of sesamol was necessary for obtaining the most potent compound The experimental process involved the reaction of Thiophene-2-sulfonyl chloride(cas: 16629-19-9Reference of Thiophene-2-sulfonyl chloride)

Thiophene-2-sulfonyl chloride(cas: 16629-19-9) is a member of sulfonyl chlorides. Sulfonyl chlorides are reactive sulfonic acid derivatives similar in properties and reactivity to acid chlorides of carboxylates. The sulfonic acid group, however, is a highly hindered molecule, containing a tetrahedral configuration of substituents. Reference of Thiophene-2-sulfonyl chloride

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

《Synthesis and antibacterial activity of some new 1,2,4-triazole derivatives bearing carbohydrazide moiety》 was written by Al-Sa’Doni, Haitham Husein; Delmani, Fatima-Azzahra; Al Balushi, Abdullah Mohammed; Al-Ahmad, Ala’A. Hamed; Alsawakhneh, Sondos Omar; Al-Soud, Yaseen Ahmad. HPLC of Formula: 16629-19-9This research focused ontriazolyl carbohydrazide preparation antibacterial activity; thione triazolyl preparation antibacterial activity. The article conveys some information:

In this study, a series of 1,2,4-triazol-3-carbohydrazide derivatives like 3-methoxy-benzoic acid N'[2-(1,5-diethyl-1H-[1,2,4]triazole3-yl)-acetyl]-hydrazide, 3,5-dinitro-benzoic acid N'[2-(1, 5-diethyl-1H-[1, 2, 4]triazole-3-yl)-acetyl]-hydrazide and compound of 1,2,4- triazole-3-(4H)-thion I (R = C6H5, 2-thienyl, 7-methoxy-4-methyl-2-oxo-2H-chromen-6-yl; R1 = Me, Et; R2 = Et) have been synthesized. Structures and purity of the new compounds I were confirmed by the use of their chromatog. and spectral data besides microanal. Four different bacterial stains for the study of the biol. activity of compounds I (R = 2,5-(Cl)2C6H3, R1 = Me, R2 = Et; R = 3-CF3C6H4, R1 = Et, R2 = Et; R = 2,5-(Cl)2C6H3, R1 = Et, R2 = Et; R = 2-thienyl, R1 = Et, R2 = Et); two Gram-pos. strains, and two Gram-neg. strains have been used. Compound I (R = 2,5-(Cl)2C6H3, R1 = Me, R2 = Et) was found to be the most active of the four tested compounds against Pseudomonas aeruginosa, Bacillus cereus and Staphylococcus aureus, with an inhibition zone diameter of 16, 9, and 10 mm, resp. Calculating the minimal inhibitory concentration value (MIC) for the pos. drugs which formed an inhibition zone in the agar well diffusion method, it was found that both I (R = 2,5-(Cl)2C6H3, R1 = Me, R2 = Et; R = 2-thienyl, R1 = Et, R2 = Et) were the most active of the four tested compounds against Pseudomonas aeruginosa and Bacillus cereus with an MIC value of 0.5μg/mL for both bacteria. These results suggest that these two compounds I (R = 2,5-(Cl)2C6H3, R1 = Me, R2 = Et; R = 2-thienyl, R1 = Et, R2 = Et) could be considered as potential antibacterial agents against a range of bacteria. In the part of experimental materials, we found many familiar compounds, such as Thiophene-2-sulfonyl chloride(cas: 16629-19-9HPLC of Formula: 16629-19-9)

Thiophene-2-sulfonyl chloride(cas: 16629-19-9) is a member of sulfonyl chlorides. Sulfonyl chlorides are reactive sulfonic acid derivatives similar in properties and reactivity to acid chlorides of carboxylates. The sulfonic acid group, however, is a highly hindered molecule, containing a tetrahedral configuration of substituents. HPLC of Formula: 16629-19-9

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

《Controlled synthesis of N,N-dimethylarylsulfonamide derivatives as nematicidal agents》 was published in Journal of Asian Natural Products Research in 2020. These research results belong to Chen, Gen-Qiang; Xia, Yan-Fei; Yang, Jin-Ming; Che, Zhi-Ping; Sun, Di; Li, Shen; Tian, Yue-E.; Liu, Sheng-Ming; Jiang, Jia; Lin, Xiao-Min. HPLC of Formula: 16629-19-9 The article mentions the following:

Gramine could be intelligently and efficiently supplied with N,N-dimethylamino group and then reacted with the corresponding sulfonyl chlorides to synthesize N,N-dimethylarylsulfonamides I [R = Ph, 4-FC6H4, 2-thienyl, etc.]. Herein designed and controlled synthesis of N,N-dimethylarylsulfonamide derivatives and first reported the results of the nematicidal activity of N,N-dimethylarylsulfonamide compounds against Meloidogyne incongnita in vitro, resp. Among all of the N,N-dimethylarylsulfonamide derivatives, compounds I [R = Ph, 4-MeOC6H4, 4-O2NC6H4, 8-quinolyl] exhibited potent nematicidal activity with median lethal concentration (LC50) values ranging from 0.22 to 0.26 mg/L. Most noteworthy, compounds I [R = 4-MeOC6H4, 8-quinolyl] showed the best promising and pronounced nematicidal activity, with LC50 values of 0.2381 and 0.2259 mg/L, resp. The experimental process involved the reaction of Thiophene-2-sulfonyl chloride(cas: 16629-19-9HPLC of Formula: 16629-19-9)

Thiophene-2-sulfonyl chloride(cas: 16629-19-9) is a member of sulfonyl chlorides. Sulfonyl chlorides are reactive sulfonic acid derivatives similar in properties and reactivity to acid chlorides of carboxylates. The sulfonic acid group, however, is a highly hindered molecule, containing a tetrahedral configuration of substituents. HPLC of Formula: 16629-19-9

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Application In Synthesis of Thiophene-2-sulfonyl chlorideIn 2022 ,《The performance of different AgTiO2 loading into poly(3-nitrothiophene) for efficient adsorption of hazardous brilliant green and crystal violet dyes》 appeared in International Journal of Polymer Science. The author of the article were Alqarni, Sara A.. The article conveys some information:

The in-situ polymerization technol. was used to successfully produce nanostructured binary nanocomposites (NCs) made from a poly(3-nitrothiophen) matrix (P3NT) that were loaded effectively with nanoparticles (NPs) of silver titanium dioxide (AgTiO2), of varying percentages (10%, 20%, and 30%). A uniform coating of P3NT covers the AgTiO2 NPs. Various methods were performed to confirm the fabrication of the binary P3NT/AgTiO2 NCs adsorbents, such as FTIR, XRD, SEM, and EDX. Both dyes (brilliant green (B.G.) and crystal violet (C.V.)) were removed from liquid media by using the binary P3NT/AgTiO2 NCs. A range of batch adsorption studies was used to optimize various factors that impact the elimination of B.G. or C.V. dyes, including the pH, weight of the binary P3NT/AgTiO2 NC, proportion of AgTiO2 NP, time, and temperature The pseudo-second-order kinetics (R2 = 0.999) was better adapted for the adsorption procedure’s empirical data whereby the maximum adsorption capacity of the C.V. dye was 43.10 mg/g and (R2 = 0.996) the maximum adsorption potential was 40.16 mg/g for B.G. dye, succeeded by the pseudo-second-order kinetics. Moreover, the adhesion of B.G. and C.V. pigments on the layers of NCs involves an endothermic reaction. In addition, the concocted adsorbent not only exhibited strong adsorption characteristics during four consecutive cycles but also possessed a higher potential for its reuse. After reading the article, we found that the author used Thiophene-2-sulfonyl chloride(cas: 16629-19-9Application In Synthesis of Thiophene-2-sulfonyl chloride)

Thiophene-2-sulfonyl chloride(cas: 16629-19-9) is a member of sulfonyl chlorides. Sulfonyl chlorides are reactive sulfonic acid derivatives similar in properties and reactivity to acid chlorides of carboxylates. The sulfonic acid group, however, is a highly hindered molecule, containing a tetrahedral configuration of substituents. Application In Synthesis of Thiophene-2-sulfonyl chloride

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics