Category: 122-18-9

Investigation on interaction of DNA and several cationic surfactants with different head groups by spectroscopy, gel electrophoresis and viscosity technologies was written by Guo, Qing;Zhang, Zhaohong;Song, Youtao;Liu, Shuo;Gao, Wei;Qiao, Heng;Guo, Lili;Wang, Jun. And the article was included in Chemosphere in 2017.Name: N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride The following contents are mentioned in the article:

In this study, the interaction between DNA and several cationic surfactants with different head groups such as Et hexadecyl di-Me ammonium bromide (EHDAB), hexadecyl di-Me benzyl ammonium chloride (HDBAC), and cetyl pyridinium bromide (CPB) were investigated by UV-vis absorption, fluorescence and CD (CD) spectroscopy, gel electrophoresis, and viscosity technologies. The results show that these cationic surfactants can interact with DNA and major binding modes are electrostatic and hydrophobic. Also, CPB and HDBAC mols. interact with DNA by partial intercalation, and CPB has slightly stronger intercalation than HDBAC, while EHDAB interacts with DNA by non-intercalation. The different head groups of the surfactant mols. can influence the interaction strength. CPB has the stronger interaction with DNA than the others. Moreover, surfactant concentration, the ratio of DNA and fluorescence probe, ionic strength can influence the interaction. The surfactants may interact with DNA by the competition reactions with BR for DNA-BR. The increase of ionic strength may favor the surface binding between DNA and surfactants to some extent. This work provides deep mechanistic insight on the toxicity of cationic surfactants with different head groups to DNA mols. This study involved multiple reactions and reactants, such as N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9Name: N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride).

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. Alkyl chlorides are versatile building blocks in organic chemistry. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available.Name: N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Fluorographene as a Mass Spectrometry Probe for High-Throughput Identification and Screening of Emerging Chemical Contaminants in Complex Samples was written by Huang, Xiu;Liu, Qian;Huang, Xiaoyu;Nie, Zhou;Ruan, Ting;Du, Yuguo;Jiang, Guibin. And the article was included in Analytical Chemistry (Washington, DC, United States) in 2017.Application In Synthesis of N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride The following contents are mentioned in the article:

Mass spectrometry techniques for high-throughput anal. of complex samples are of profound importance in many areas such as food safety, omics studies, and environmental health science. Here the authors report the use of fluorographene (FG) as a new mass spectrometry probe for high-throughput identification and screening of emerging chem. contaminants in complex samples. FG was facilely synthesized by 1-step exfoliation of fluorographite. With FG as a matrix or probe in matrix-assisted or surface-enhanced laser desorption/ionization time-of-flight mass spectrometry (MALDI- or SELDI-TOF MS), higher sensitivity (detection limits at ppt or subppt levels), and better reproducibility were achieved than with other graphene-based materials due to the unique chem. structure and self-assembly properties of FG. The method was validated with different types of real complex samples. By using FG as a SELDI probe, the authors could easily detect trace amount of bisphenol S in paper products and high-fat canned food samples. Also, the authors have successfully identified and screened as many as 28 quaternary ammonium halides in sewage sludge samples collected from municipal wastewater treatment plants. FG probe is a powerful tool for high-throughput anal. of complex samples by MS. This study involved multiple reactions and reactants, such as N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9Application In Synthesis of N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride).

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. The hydrocarbon processing industry (HPI) and others are affected by damage caused by these substances. Organochlorine compounds are lipophylic, meaning they are more soluble in fat than in water. This gives them a high tenancy to accumulate in the food chain (biomagnification).Application In Synthesis of N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Quaternary Ammonium Compounds: Bioaccumulation Potentials in Humans and Levels in Blood before and during the Covid-19 Pandemic was written by Zheng, Guomao;Webster, Thomas F.;Salamova, Amina. And the article was included in Environmental Science & Technology in 2021.Recommanded Product: 122-18-9 The following contents are mentioned in the article:

Quaternary ammonium compounds (QACs) are commonly used in a variety of consumer, pharmaceutical, and medical products. In this study, bioaccumulation potentials of 18 QACs with alkyl chain lengths of C8-C18 were determined in the in vitro-in vivo extrapolation (IVIVE) model using the results of human hepatic metabolism and serum protein binding experiments The slowest in vivo clearance rates were estimated for C12-QACs, suggesting that these compounds may preferentially build up in blood. The bioaccumulation of QACs was further confirmed by the anal. of human blood (sera) samples (n = 222). Fifteen out of the 18 targeted QACs were detected in blood with the ΣQAC concentrations reaching up to 68.6 ng/mL. The blood samples were collected during two distinct time periods: before the outbreak of the COVID-19 pandemic (2019; n = 111) and during the pandemic (2020, n = 111). The ΣQAC concentrations were significantly higher in samples collected during the pandemic (median 6.04 ng/mL) than in those collected before (median 3.41 ng/mL). This is the first comprehensive study on the bioaccumulation and biomonitoring of the three major QAC groups and our results provide valuable information for future epidemiol., toxicol., and risk assessment studies targeting these chems. This study involved multiple reactions and reactants, such as N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9Recommanded Product: 122-18-9).

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids.While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.Recommanded Product: 122-18-9

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Surface chemistry interactions of cationorm with films by human meibum and tear film compounds was written by Georgiev, Georgi As.;Yokoi, Norihiko;Nencheva, Yana;Peev, Nikola;Daull, Philippe. And the article was included in International Journal of Molecular Sciences in 2017.Name: N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride The following contents are mentioned in the article:

Cationorm (CN) cationic nanoemulsion was demonstrated to enhance tear film (TF) stability in vivo possibly via effects on tear film lipid layer (TFLL). Therefore the interactions of CN with human meibum (MGS) and TFLL in vitro and in vivo deserve special study. MGS and CN were spread at the air/water interface of a Langmuir surface balance to ensure a range of MGS/CN oil phase ratios: 20/1, 10/1, 5/1, 3/1, 2/1 and 1/1. The films capability to reorganize during dynamic area changes was evaluated via the surface pressure-area compression isotherms and step/relaxation dilatational rheol. studies. Films structure was monitored with Brewster angle microscopy. CN/TFLL interactions at the ocular surface were monitored with non-contact specular microscopy. The in vitro studies of MGS/CN layers showed that (i) CN inclusion (at fixed MGS content) increased film elasticity and thickness and that (ii) CN can compensate for moderate meibum deficiency in MGS/CN films. In vivo CN mixed with TFLL in a manner similar to CN/MGS interactions in vitro, and resulted in enhanced thickness of TFLL. In vitro and in vivo data complement each other and facilitated the study of the composition-structure-function relationship that determines the impact of cationic nanoemulsions on TF. This study involved multiple reactions and reactants, such as N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9Name: N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride).

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. The hydrocarbon processing industry (HPI) and others are affected by damage caused by these substances. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.Name: N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

A simple one-step procedure to synthesise gold nanostars in concentrated aqueous surfactant solutions was written by Liebig, Ferenc;Henning, Ricky;Sarhan, Radwan M.;Prietzel, Claudia;Schmitt, Clemens N. Z.;Bargheer, Matias;Koetz, Joachim. And the article was included in RSC Advances in 2019.Safety of N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride The following contents are mentioned in the article:

Due to the enhanced electromagnetic field at the tips of metal nanoparticles, the spiked structure of gold nanostars (AuNSs) is promising for surface-enhanced Raman scattering (SERS). Therefore, the challenge is the synthesis of well designed particles with sharp tips. The influence of different surfactants, i.e., dioctyl sodium sulfosuccinate (AOT), sodium dodecyl sulfate (SDS), and benzylhexadecyldimethylammonium chloride (BDAC), as well as the combination of surfactant mixtures on the formation of nanostars in the presence of Ag⁺ ions and ascorbic acid was investigated. By varying the amount of BDAC in mixed micelles the core/spike-shell morphol. of the resulting AuNSs can be tuned from small cores to large ones with sharp and large spikes. The concomitant red-shift in the absorption toward the NIR region without losing the SERS enhancement enables their use for biol. applications and for time-resolved spectroscopic studies of chem. reactions, which require a permanent supply with a fresh and homogeneous solution HRTEM micrographs and energy-dispersive X-ray (EDX) experiments allow us to verify the mechanism of nanostar formation according to the silver underpotential deposition on the spike surface in combination with micelle adsorption. This study involved multiple reactions and reactants, such as N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9Safety of N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride).

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. The hydrocarbon processing industry (HPI) and others are affected by damage caused by these substances. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst.Safety of N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Improving stability of tear film lipid layer via concerted action of two drug molecules: a biophysical view was written by Eftimov, Petar;Olzynska, Agnieszka;Melcrova, Adela;Georgiev, Georgi As.;Daull, Philippe;Garrigue, Jean-Sebastien;Cwiklik, Lukasz. And the article was included in International Journal of Molecular Sciences in 2020.Synthetic Route of C25H46ClN The following contents are mentioned in the article:

The tear film at the ocular surface is covered by a thin layer of lipids. This oily phase stabilizes the film by decreasing its surface tension and improving its viscoelastic properties. Clin., destabilization and rupture of the tear film are related to dry eye disease and are accompanied by changes in the quality and quantity of tear film lipids. In dry eye, eye drops containing oil-in-water emulsions are used for the supplementation of lipids and surface-active components to the tear film. We explore in detail the biophys. aspects of interactions of sp. surface-active compounds, cetalkonium chloride and poloxamer 188, which are present in oil-in-water emulsions, with tear lipids. The aim is to better understand the macroscopically observed eye drops-tear film interactions by rationalizing them at the mol. level. To this end, we employ a multi-scale approach combining experiments on human meibomian lipid extracts, measurements using synthetic lipid films, and in silico mol. dynamics simulations. By combining these methods, we demonstrate that the studied compounds specifically interact with the tear lipid film enhancing its structure, surfactant properties, and elasticity. The observed effects are cooperative and can be further modulated by material packing at the tear-air interface. This study involved multiple reactions and reactants, such as N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9Synthetic Route of C25H46ClN).

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. An organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst.Synthetic Route of C25H46ClN

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Use of capillary electrophoresis for characterisation of vinyl-terminated Au nanoprisms and nanooctahedra was written by Adelantado, Carlos;Algarra, Manuel;Zougagh, Mohammed;Rios, Angel. And the article was included in Electrophoresis in 2018.Electric Literature of C25H46ClN The following contents are mentioned in the article:

It is described a simple, rapid and efficient methodol. to characterize and sep. gold nanoprisms and nanooctahedra by capillary electrophoresis. This technique is suitable to distinguish between morphologies and it can be used as a powerful separation tool after a customised synthesis of both structures. This synthesis was carried out by amending two parameters, temperature and pH, and a sharp decrease was found in nanotriangles when temperature was increased from 70 up to 95°. However, when the synthesis was performed at a given temperature, an increase in pH did not promote an important change in isolation of any structure until pH = 9.5, critical in the final morphol. of the nanoparticle. Gold nanoprisms and nanooctahedra were successfully separated by capillary electrophoresis according to differences in charge-to-mass ratio of the morphologies. Final particle morphol. was confirmed by TEM anal. Under optimal working conditions, a mixture containing both shapes of gold nanoparticles was initially injected and two major peaks were obtained for each structure. Capillary electrophoresis allowed to study pH and temperature influence on both morphologies. It was inferred that the ratio between triangles and octahedra decreased to a great extent when increasing both temperature and pH. This study involved multiple reactions and reactants, such as N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9Electric Literature of C25H46ClN).

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. The hydrocarbon processing industry (HPI) and others are affected by damage caused by these substances. Organochlorine compounds are lipophylic, meaning they are more soluble in fat than in water. This gives them a high tenancy to accumulate in the food chain (biomagnification).Electric Literature of C25H46ClN

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Detection of intracellular lamellar bodies as a screening marker for fibrotic lesions was written by Park, Eun-Jung;Kang, Min-Sung;Lim, Hyun-Ji;Kang, Tae Kyu;Jin, Seung-Woo;Lee, Seung Hyeun;Baek, Sun Hwa;Kang, Jeong Won. And the article was included in Toxicology and Applied Pharmacology in 2021.Synthetic Route of C25H46ClN The following contents are mentioned in the article:

With the rapid increase in application of disinfectants worldwide as a method to block the spread of coronavirus, many new products are being introduced into the market without thorough verification of their impacts on human health and the environment. In the present study, we aimed to propose a screening marker for materials that can induce fibrotic lung disease using disinfectants, which had been demonstrated as causative materials of chronic inflammation and interstitial fibrosis. We first calculated the corresponding LC50 level based on results from cell viability test and exposed the LC50 level of disinfectants to human bronchial epithelial cells for 24 h. Formation of lamellar body-like structures, cleavage of the nuclear matrix, structural damage of mitochondria were found in the cytosol of the treated cells. We also dosed disinfectants by pharyngeal aspiration to mice to determine the LD0 level. The mice were sacrificed on Day 14 after a single dosing, and lamellar body-like structures were observed in the lung tissue of mice. Herein, we hypothesize that DNA damage and metabolic disturbance may play central roles in disinfectant-induced adverse health effects. Addnl., we propose that formation of lamellar bodies can be a screening marker for interstitial fibrosis. This study involved multiple reactions and reactants, such as N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9Synthetic Route of C25H46ClN).

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. The hydrocarbon processing industry (HPI) and others are affected by damage caused by these substances. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control.Synthetic Route of C25H46ClN

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Oxygen consumption rate of Caenorhabditis elegans as a high-throughput endpoint of toxicity testing using the Seahorse XF^e96 Extracellular Flux Analyzer was written by Du Preez, G.;Fourie, H.;Daneel, M.;Miller, H.;Hoss, S.;Ricci, C.;Engelbrecht, G.;Zouhar, M.;Wepener, V.. And the article was included in Scientific Reports in 2020.Related Products of 122-18-9 The following contents are mentioned in the article:

Abstract: Caenorhabditis elegans presents functioning, biol. relevant phenotypes and is frequently used as a bioindicator of toxicity. However, most C. elegans in vivo effect-assessment methods are laborious and time consuming. Therefore, we developed a novel method to measure the oxygen consumption rate of C. elegans as a sublethal endpoint of toxicity. This protocol was tested by exposing 50 larval stage one C. elegans individuals for 48 h (at 20°C) to different concentrations of two toxicants i.e. benzylcetyldimethylammonium chloride (BAC-C16) and cadmium (Cd). Following exposures, the oxygen consumption rate of the C. elegans individuals were measured using the high-throughput functionality of the Seahorse XF^e96 Extracellular Flux Analyzer. Dose-response curves for BAC-C16 (R² = 0.93; P = 0.001) and Cd (R² = 0.98; P = 0.001) were created. Furthermore, a strong, pos. correlation was evidenced between C. elegans oxygen consumption rate and a commonly used, ecol. relevant endpoint of toxicity (growth inhibition) for BAC-C16 (R² = 0.93; P = 0.0001) and Cd (R² = 0.91; P = 0.0001). The data presented in this study show that C. elegans oxygen consumption rate can be used as a promising functional measurement of toxicity. This study involved multiple reactions and reactants, such as N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9Related Products of 122-18-9).

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. The hydrocarbon processing industry (HPI) and others are affected by damage caused by these substances. Organochlorine compounds are lipophylic, meaning they are more soluble in fat than in water. This gives them a high tenancy to accumulate in the food chain (biomagnification).Related Products of 122-18-9

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Enhancement of adsorption efficiency of heavy metal Cu(II) and Zn(II) onto cationic surfactant modified bentonite was written by Tohdee, Kanogwan;Kaewsichan, Lupong;Asadullah. And the article was included in Journal of Environmental Chemical Engineering in 2018.Reference of 122-18-9 The following contents are mentioned in the article:

This study sought to enhance the metal adsorption capacity of bentonite by improving its surfaces. Surface modification by the cationic surfactant (Bencylhexadecyldimethyl ammonium chloride, BCDMACl) was successful in this respect, and was characterized by FTIR spectroscopy, XRF, BET, and swelling test. A major characteristic of BCDMACl is forming micelles that can intercalate into interlayers of clay and prevent swelling. The adsorption of Cu (II) and Zn (II) from aqueous solutions was studied in batch experiments, varying both contact time and concentrations of the metal ions. Retention of the metals in solution was detected by Atomic Absorption Spectroscopy (AAS). The adsorption data were fitted with Langmuir, Freundlich, and Dubinin-Radushkevich isotherm models, of which the Langmuir isotherm provided the best fit with exptl. data (R² range 0.962-0.993). The results also revealed that the modified bentonite had significantly improved adsorption capacities (q_max 50.76 and 35.21mg/g for Cu(II) and Zn(II), resp.); about 2.5 and 2.0 fold improvements over natural bentonite. The pseudo-second-order rate equation provided the best fit to observed adsorption kinetics. This study demonstrated the modified bentonite as an effective adsorbent for the removal of heavy metals from aqueous solutions This study involved multiple reactions and reactants, such as N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9Reference of 122-18-9).

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. The hydrocarbon processing industry (HPI) and others are affected by damage caused by these substances. Alkyl chlorides are versatile building blocks in organic chemistry. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available.Reference of 122-18-9

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics