Di Ianni, Emilio et al. published their research in Nanotoxicology in 2020 | CAS: 122-18-9

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. Organochlorines stimulate the central nervous system and cause convulsions, tremor, nausea, and mental confusion. Examples are dichlorodiphenyltrichloroethane (DDT), chlordane, lindane, endosulfan, and dieldrin. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.Safety of N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride

Organomodified nanoclays induce less inflammation, acute phase response, and genotoxicity than pristine nanoclays in mice lungs was written by Di Ianni, Emilio;Moeller, Peter;Mortensen, Alicja;Szarek, Jozef;Clausen, Per Axel;Saber, Anne Thoustrup;Vogel, Ulla;Jacobsen, Nicklas Raun. And the article was included in Nanotoxicology in 2020.Safety of N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride The following contents are mentioned in the article:

Surface modification by different quaternary ammonium compounds (QAC) makes nanoclays more compatible with various polymeric matrixes, thereby expanding their potential applications. The growing industrial use of nanoclays could potentially pose a health risk for workers. Here, we assessed how surface modification of nanoclays modulates their pulmonary toxicity. An in vitro screening of the unmodified nanoclay Bentonite (montmorillonite) and four organomodified nanoclays (ONC); coated with various QAC, including benzalkonium chloride (BAC), guided the selection of the materials for the in vivo study. Mice were exposed via a single intratracheal instillation to 18, 54, and 162 μg of unmodified Bentonite or dialkyldimethyl-ammonium-coated ONC (NanofilSE3000), or to 6, 18, and 54 μg of a BAC-coated ONC (Nanofil9), and followed for one, 3, or 28 days. All materials induced dose- and time-dependent responses in the exposed mice. However, all doses of Bentonite induced larger, but reversible, inflammation (BAL neutrophils) and acute phase response (Saa3 gene expression in lung) than the two ONC. Similarly, highest levels of DNA strand breaks were found in BAL cells of mice exposed to Bentonite 1 day post-exposure. A significant increase of DNA strand breaks was detected also for NanofilSE3000, 3 days post-exposure. Only mice exposed to Bentonite showed increased Tgf-β gene expression in lung, biomarker of pro-fibrotic processes and hepatic extravasation, 3 days post-exposure. This study indicates that Bentonite treatment with some QAC changes main phys.-chem. properties, including shape and surface area, and may decrease their pulmonary toxicity in exposed mice. This study involved multiple reactions and reactants, such as N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9Safety of N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride).

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. Organochlorines stimulate the central nervous system and cause convulsions, tremor, nausea, and mental confusion. Examples are dichlorodiphenyltrichloroethane (DDT), chlordane, lindane, endosulfan, and dieldrin. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.Safety of N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Fernandes, Susana et al. published their research in Food Research International in 2020 | CAS: 122-18-9

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. Organochlorines are organic compounds having multiple chlorine atoms. They were the first synthetic pesticides that were used in agriculture. They are resistant to most microbial and chemical degradations. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control.Computed Properties of C25H46ClN

Antimicrobial activity of glycolic acid and glyoxal against Bacillus cereus and Pseudomonas fluorescens was written by Fernandes, Susana;Gomes, Ines B.;Simoes, Manuel. And the article was included in Food Research International in 2020.Computed Properties of C25H46ClN The following contents are mentioned in the article:

The development of effective disinfection strategies, including the search for new active biocides, is a priority research for the food industry. Glycolic acid (GA) and glyoxal (GO) are two glycolysis byproducts approved as biocides for surface disinfection, whose antimicrobial action remains to be understood. This study focused on the understanding of the antimicrobial activity of GA and GO against two foodborne pathogens, Bacillus cereus and Pseudomonas fluorescens. Benzalkonium chloride (BAC) and peracetic acid (PAA) were used as reference biocides for comparison. The influence of biocide concentration and exposure time on the antimicrobial activity of the selected biocides was evaluated based on the European Standard EN 1276. The mode of action of each biocide was characterized based on their effects on the cell envelope and cell replication. According to the Chick-Watson model, all biocides interacted chem. with cell targets of both bacteria, except GO that only stablished physicochem. interactions with P. fluorescens. The survival curves revealed that high concentrations of biocide induced readily effects on cell culturability. The susceptibility profile of P. fluorescens was constant over time. In general, B. cereus increased tolerance to BAC and became more susceptible to cumulative damages of GA. Overall, this study demonstrates that the biocidal activity was species-, dose- and time-dependent. GA, similarly to BAC, was a membrane-active and oxidant agent. GO had no effect on the bacterial surface as well as PAA. GO was mainly categorized as a cell replication inhibitor. For the first time, the antimicrobial activity of GA and GO were characterized revealing their potential for rational combination with other biocides commonly used in the food industry. This study involved multiple reactions and reactants, such as N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9Computed Properties of C25H46ClN).

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. Organochlorines are organic compounds having multiple chlorine atoms. They were the first synthetic pesticides that were used in agriculture. They are resistant to most microbial and chemical degradations. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control.Computed Properties of C25H46ClN

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Silva Thomsen, Lars Bjoern et al. published their research in Water Research in 2020 | CAS: 122-18-9

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. An organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. Alkyl chlorides readily react with amines to give substituted amines. Alkyl chlorides are substituted by softer halides such as the iodide in the Finkelstein reaction.Recommanded Product: N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride

Hydrothermal liquefaction of sewage sludge; energy considerations and fate of micropollutants during pilot scale processing was written by Silva Thomsen, Lars Bjoern;Carvalho, Pedro N.;dos Passos, Juliano Souza;Anastasakis, Konstantinos;Bester, Kai;Biller, Patrick. And the article was included in Water Research in 2020.Recommanded Product: N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride The following contents are mentioned in the article:

The beneficial use of sewage sludge for valorization of carbon and nutrients is of increasing interest while micropollutants in sludge are of concern to the environment and human health. This study investigates the hydrothermal liquefaction (HTL) of sewage sludge in a continuous flow pilot scale reactor at conditions expected to reflect future industrial installations. The processing is evaluated in terms of energy efficiency, bio-crude yields and quality. The raw sludge and post-HTL process water and solid residues were analyzed extensively for micropollutants via HPLC-MS/MS for target pharmaceuticals including antibiotics, blood pressure medicine, antidepressants, analgesics, x-ray contrast media, angiotensin II receptor blockers, immunosuppressant drugs and biocides including triazines, triazoles, carbamates, a carboxamide, an organophosphate and a cationic surfactant. The results show that a pos. energy return on investment was achieved for all three HTL processing temperatures of 300, 325 and 350°C with the most beneficial temperature identified as 325°C. The anal. of the HTL byproducts, process water and solids, indicates that HTL is indeed a suitable technol. for the destruction of micropollutants. However, due to the large matrix effect of the HTL process water it can only be stated with certainty that 9 out of 30 pharmaceuticals and 5 out of 7 biocides products were destroyed successfully (over 98% removal). One compound, the antidepressant citalopram, was shown to be moderately recalcitrant at 300°C with 87% removal and was only destroyed at temperatures≥325°C (>99% removal). Overall, the results suggest that HTL is a suitable technol. for energy efficient and value added sewage sludge treatment enabling destruction of micropollutants. This study involved multiple reactions and reactants, such as N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9Recommanded Product: N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride).

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. An organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. Alkyl chlorides readily react with amines to give substituted amines. Alkyl chlorides are substituted by softer halides such as the iodide in the Finkelstein reaction.Recommanded Product: N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Molla, Mohammad Robel et al. published their research in Journal of Surfactants and Detergents in 2018 | CAS: 122-18-9

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. Organochlorines are organic compounds having multiple chlorine atoms. They were the first synthetic pesticides that were used in agriculture. They are resistant to most microbial and chemical degradations. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control.Name: N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride

Conductometric Probe Analysis of the Effect of Benzyldimethylhexadecylammonium Chloride on the Micellization Behavior of Dodecyltrimethylammonium Bromide in Aqueous/Urea Solution: Investigation of Concentration and Temperature Effect was written by Molla, Mohammad Robel;Rana, Shahed;Abdul Rub, Malik;Ahmed, Anwar;Hoque, Anamul Md.. And the article was included in Journal of Surfactants and Detergents in 2018.Name: N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride The following contents are mentioned in the article:

Surfactant mixtures are used in many different industrial formulations. In this study, the mixed micelle formation behavior of 2 different cationic surfactants, namely dodecyltrimethylammonium bromide (DTAB) and benzyldimethylhexadecylammonium chloride (BDHAC), in the absence and presence of urea at various temperatures (298.15-318.15 K) was studied using the conductometric method. The attractive interaction between DTAB and BDHAC was estimated from the values of critical micelle concentration (CMC) and the CMC for ideal mixing (CMCid). Urea increases the CMC value as a result of the enrichment in the surface charge of the micelles/mixed micelles. The values of micellar mole fraction (X1Rub [Rubingh], X1M [Motomura], X1Rod [Rodenas]) and ideal micellar (X1id) of surfactant BDHAC were obtained by different models and are shown to exhibit the high contribution or effective involvement of BDHAC in mixed micelles and increase with increasing BDHAC mole fraction (a1). Activity coefficients (f1 and f2) were also evaluated from the relevant formula given in the literature. The neg. values of the interaction parameters (β) show the attractive interaction among the studied components. Excess Gibbs free energy ([Δ]Gex) of micellization revealed that the stability of mixed micelles is higher in aqueous solution than in urea solution The thermodn. parameters, namely the Gibbs free energy change, enthalpy change, and entropy change ([Δ]Gom, ΔHom, and [Δ]Som, resp.), were also calculated from the conventional standard equations. This study involved multiple reactions and reactants, such as N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9Name: N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride).

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. Organochlorines are organic compounds having multiple chlorine atoms. They were the first synthetic pesticides that were used in agriculture. They are resistant to most microbial and chemical degradations. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control.Name: N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Groothuis, Floris A. et al. published their research in Chemical Research in Toxicology in 2019 | CAS: 122-18-9

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. Organochlorines are organic compounds having multiple chlorine atoms. They were the first synthetic pesticides that were used in agriculture. They are resistant to most microbial and chemical degradations. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.Quality Control of N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride

Influence of in Vitro Assay Setup on the Apparent Cytotoxic Potency of Benzalkonium Chlorides was written by Groothuis, Floris A.;Timmer, Niels;Opsahl, Eystein;Nicol, Beate;Droge, Steven T. J.;Blaauboer, Bas J.;Kramer, Nynke I.. And the article was included in Chemical Research in Toxicology in 2019.Quality Control of N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride The following contents are mentioned in the article:

The nominal concentration is generally used to express concentration-effect relationships in in vitro toxicity assays. However, the nominal concentration does not necessarily represent the exposure concentration responsible for the observed effect. Surfactants accumulate at interphases and likely sorb to in vitro system components such as serum protein and well plate plastic. The extent of sorption and the consequences of this sorption on in vitro readouts is largely unknown for these chems. The aim of this study was to demonstrate the effect of sorption to in vitro components on the observed cytotoxic potency of benzalkonium chlorides (BAC) varying in alkyl chain length (6-18 carbon atoms, C6-18) in a basal cytotoxicity assay with the rainbow trout gill cell line (RTgill-W1). Cells were exposed for 48h in 96-well plates to increasing concentration of BACs in exposure medium containing 0, 60 μM Bovine Serum Albumin (BSA) or 10% fetal bovine serum (FBS). Before and after exposure, BAC concentrations in exposure medium were anal. determined Based on freely dissolved concentrations at the end of the exposure, median effect concentrations (EC50) decreased with increasing alkyl chain length up to 14 carbons. For BAC with alkyl chains of twelve or more carbons, EC50s based on measured concentrations after exposure in supplement-free medium were up to 25-times lower than EC50 calculated using nominal concentrations When BSA or FBS was added to the medium, a decrease in cytotoxic potency of up to 22 times was observed for BAC with alkyl chains of eight or more carbons. The results of this study emphasize the importance of expressing the in vitro readouts as a function of a dose metric that is least influenced by assay setup to compare assay sensitivities and chem. potencies. This study involved multiple reactions and reactants, such as N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9Quality Control of N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride).

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. Organochlorines are organic compounds having multiple chlorine atoms. They were the first synthetic pesticides that were used in agriculture. They are resistant to most microbial and chemical degradations. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.Quality Control of N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Vitkova, Zuzana et al. published their research in Molecules in 2017 | CAS: 122-18-9

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.COA of Formula: C25H46ClN

Association, distribution, liberation, and rheological balances of alkyldimethylbenzylammonium chlorides (C12-C16) was written by Vitkova, Zuzana;Oremusova, Jarmila;Herdova, Petra;Ivankova, Ol’ga;Vitko, Anton. And the article was included in Molecules in 2017.COA of Formula: C25H46ClN The following contents are mentioned in the article:

It is known that cationic surfactants have an antimicrobial effect and act as enhancers. This paper studies three cationic surfactants from the group of alkyldimethylbenzylammonium chlorides (dodecyl-, tetradecyl-, and hexadecyl). Interest is focused on the association of the surfactants with respect to temperature, partition balances and their influence on drug release, rheol. properties, and the pH of hydrogels. The critical micelle concentrations (CMC) of the surfactants were estimated from dependencies of conductivity, d., spectrofluorimetry, and UV-VIS spectrophotometry on molarity in the temperature range of 25-50°C. It was found that the temperature dependence of a CMC is U-shaped, with its min. at 30°C, and the CMC value decreases as the length of the chain increases. The pseudo-phase separation model was used for the calculation of various thermodn. parameters, such as the Gibbs free energies (spontaneous process), enthalpies (exothermic process), and entropies of the micelles’ formation, CMCs, and the degree of counterion binding. All thermodn. parameters, as functions of the temperature, were estimated It was found that partition coefficients increase as the length of the alkyl chain and the pH = (5.0-7.0) increase. The influences of surfactants, below and above the CMC, on drug (chlorhexidine dihydrochloride) release from hydrogels, rheol. properties, and pH at 30°C were studied. Also, the amounts of the released drug increase as the alkyl chains of the surfactants prolongate. The amounts of the released drug with the surfactant below the CMC are greater than that above the CMC. All hydrogels (regardless of the length of the alkyl chain) exhibit a non-Newtonian pseudo-plastic flow. The results obtained will be used in the formulation of the drug and surfactants into dosage forms. This study involved multiple reactions and reactants, such as N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9COA of Formula: C25H46ClN).

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.COA of Formula: C25H46ClN

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Dutescu, Ralf M. et al. published their research in Journal of Ocular Pharmacology and Therapeutics in 2020 | CAS: 122-18-9

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. Chlorination modifies the physical properties of hydrocarbons in several ways. These compounds are typically denser than water due to the higher atomic weight of chlorine versus hydrogen. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.Reference of 122-18-9

High-Frequency Application of Cationic Agents Containing Lubricant Eye Drops Causes Cumulative Corneal Toxicity in an Ex Vivo Eye Irritation Test Model was written by Dutescu, Ralf M.;Uthoff, Daniel;Panfil, Claudia;Schrage, Norbert. And the article was included in Journal of Ocular Pharmacology and Therapeutics in 2020.Reference of 122-18-9 The following contents are mentioned in the article:

Purpose: High-frequency applied cetalkonium chloride (CAC) and benzalkonium chloride (BAC) 0.02% did not hamper corneal healing in a living rabbit model of induced corneal erosion. In contrast, the ex vivo eye irritation test (EVEIT) shows inhibition of healing for these substances. In a systematic ex vivo reproduction of the in vivo experiments, we discuss the background of these differences. Methods: Excised rabbit corneas (n = 5 per group) were cultured in artificial anterior chambers (EVEIT). Four erosions were induced for each cornea before starting regular 21 installations/day over 3 days of (1) CAC containing eye drops (Cationorm), (2) 0.02% BAC. Corneal fluorescein staining, quantification of glucose-/lactate consumption, and histol. were performed. Results: BAC 0.02% treated corneas showed increased epithelial lesions from 10.13 ± 0.65 mm2 to 10 ± 0.8 mm2 on day 0, to 86.82 ± 5.18 mm2 (P < 0.0001) by day 3. After a trend toward smaller lesions for CAC on day 1, erosion sizes increased significantly by day 3 from 9.82 ± 0.30 mm2 to 29.51 ± 16.87 mm2 (P < 0.05). For 1 cornea, corneal erosions nearly disappeared on day 3 (0.89 mm2). Corneal lactate increased significantly for BAC and CAC, whereas glucose concentrations were unchanged. Histol. revealed disintegration of the corneal structures for both compounds Conclusions: The data underline the EVEIT as a predictive toxicity test to show side effects in a time-compressed manner. The consistency of these predictions was previously demonstrated by the EVEIT for BAC, phosphate buffer, and others. The EVEIT is suited for a chronic application prediction of tolerability and toxic side effects of eye drops in particular, and other chems. in general. This study involved multiple reactions and reactants, such as N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9Reference of 122-18-9).

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. Chlorination modifies the physical properties of hydrocarbons in several ways. These compounds are typically denser than water due to the higher atomic weight of chlorine versus hydrogen. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.Reference of 122-18-9

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Lutz-Bueno, Viviane et al. published their research in Langmuir in 2017 | CAS: 122-18-9

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. Alkyl chlorides readily react with amines to give substituted amines. Alkyl chlorides are substituted by softer halides such as the iodide in the Finkelstein reaction.Category: chlorides-buliding-blocks

Intermicellar Interactions and the Viscoelasticity of Surfactant Solutions: Complementary Use of SANS and SAXS was written by Lutz-Bueno, Viviane;Liebi, Marianne;Kohlbrecher, Joachim;Fischer, Peter. And the article was included in Langmuir in 2017.Category: chlorides-buliding-blocks The following contents are mentioned in the article:

In ionic surfactant micelles, basic interactions among distinct parts of surfactant monomers, their counterion, and additives are fundamental to tuning mol. self-assembly and enhancing viscoelasticity. The authors investigate the addition of sodium salicylate (NaSal) to hexadecyltrimethylammonium chloride and bromide (CTAC and CTAB) and 1-hexadecylpyridinium chloride and bromide (CPyCl and CPyBr), which have distinct counterions and headgroup structures but the same hydrophobic tail. Different contrasts are obtained from small-angle neutron scattering (SANS), which probes differences between the nucleus of atoms, and X-rays SAXS, which probes differences in electron d. If combined, this contrast allows us to define specific intramicellar length scales and intermicellar interactions. SANS signals are sensitive to the contrast between the solvent (D2O) and the hydrocarbonic tails in the micellar core (hydrogen), and SAXS can access the inner structure of the polar shell because the headgroups, counterions, and penetrated salt have higher electron densities compared to the solvent and to the micellar core. The number d., intermicellar distances, aggregation number, and inter/intramicellar repulsions are discussed on the basis of the dependence of the structure factor and form factor on the micellar aggregate morphol. Therefore, we confirm that micellar growth can be tuned by variations in the flexibility and size of the headgroup as well as the ionic dissociation rate of its counterion. Addnl., we show that the counterion binding is even more significant to the development of viscoelasticity than the headgroup structure of a surfactant mol. This is a surprising finding, showing the importance of electrostatic charges in the self-assembly process of ionic surfactant mols. This study involved multiple reactions and reactants, such as N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9Category: chlorides-buliding-blocks).

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. Alkyl chlorides readily react with amines to give substituted amines. Alkyl chlorides are substituted by softer halides such as the iodide in the Finkelstein reaction.Category: chlorides-buliding-blocks

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Sarcina, Lucia et al. published their research in Nanomaterials in 2020 | CAS: 122-18-9

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. An organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications.While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.HPLC of Formula: 122-18-9

Cu nanoparticle-loaded nanovesicles with antibiofilm properties. Part I: synthesis of new hybrid nanostructures was written by Sarcina, Lucia;Manrique, Pablo Garcia;Gutierrez, Gemma;Ditaranto, Nicoletta;Cioffi, Nicola;Matos, Maria;del Carmen Blanco-Lopez, Maria. And the article was included in Nanomaterials in 2020.HPLC of Formula: 122-18-9 The following contents are mentioned in the article:

Copper nanoparticles (CuNPs) stabilized by quaternary ammonium salts are well known as antimicrobial agents. The aim of this work was to study the feasibility of the inclusion of CuNPs in nanovesicular systems. Liposomes are nanovesicles (NVs) made with phospholipids and are traditionally used as delivery vehicles because phospholipids favor cellular uptake. Their capacity for hydrophilic/hydrophobic balance and carrier capacity could be advantageous to prepare novel hybrid nanostructures based on metal NPs (Me-NPs). In this work, NVs were loaded with CuNPs, which have been reported to have a biofilm inhibition effect. These hybrid materials could improve the effect of conventional antibacterial agents. CuNPs were electro-synthesized by the sacrificial anode electrolysis technique in organic media and characterized in terms of morphol. through transmission electron microscopy (TEM). The NVs were prepared by the thin film hydration method in aqueous media, using phosphatidylcholine (PC) and cholesterol as a membrane stabilizer. The nanohybrid systems were purified to remove non-encapsulated NPs. The size distribution, morphol. and stability of the NV systems were studied. Different quaternary ammonium salts in vesicular systems made of PC were tested as stabilizing surfactants for the synthesis and inclusion of CuNPs. The entrapment of charged metal NPs was demonstrated. NPs attached preferably to the membrane, probably due to the attraction of their hydrophobic shell to the phospholipid bilayers. The high affinity between benzyl-dimethyl-hexadecyl-ammonium chloride (BDHAC) and PC allowed us to obtain stable hybrid NVs c.a. 700 nm in diameter The stability of liposomes increased with NP loading, suggesting a charge-stabilization effect in a novel antibiofilm nanohybrid material. This study involved multiple reactions and reactants, such as N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9HPLC of Formula: 122-18-9).

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. An organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications.While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.HPLC of Formula: 122-18-9

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Porcal, Gabriela V. et al. published their research in Journal of Photochemistry and Photobiology, A: Chemistry in 2017 | CAS: 122-18-9

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. Chlorination modifies the physical properties of hydrocarbons in several ways. These compounds are typically denser than water due to the higher atomic weight of chlorine versus hydrogen. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.HPLC of Formula: 122-18-9

Photophysics of thionine in AOT and BHDC reverse micelles. Quenching of the triplet state by aliphatic amines studied by transient absorption spectroscopy was written by Porcal, Gabriela V.;Arbeloa, Ernesto M.;Bertolotti, Sonia G.;Previtali, Carlos M.. And the article was included in Journal of Photochemistry and Photobiology, A: Chemistry in 2017.HPLC of Formula: 122-18-9 The following contents are mentioned in the article:

The photophysics of thionine (3,7-diamino-5-phenothiazinium) (Th+) was investigated in reverse micelles (RMs) of sodium bis(2-ethylhexyl)sulfosuccinate (AOT) and benzyldimethylhexadecylammonium chloride (BHDC) with special emphasis on the triplet state processes. In RMs both the absorption and emission spectra of the dye present a red shift with respect to pure water. The absorption maximum wavelength and Stokes shift show a tendency towards the values in water, although do not reach them even with the higher water content examined The photophys. parameters are more affected by the water content in BHDC than in AOT. The triplet state of Th+ was investigated by the technique of laser flash photolysis. The T-T absorption spectrum presents a strong absorption band in the region between 770 and 800 nm, corresponding to the monoprotonated triplet form of the dye. This spectrum is red shifted with respect to water in the RMs. The triplet quenching by aliphatic amines was investigated. The triplet decay is well fitted by a bi-exponential function in the presence of the hydro-soluble triethanolamine (TEOA) in both RMs. This behavior is interpreted as the result of a very fast intramicellar quenching, followed by slow process that may be ascribed to an intermicellar exchange of amine mols. between RMs. The kinetic anal. showed that intermicellar exchange rate constant is two orders of magnitude more effective in BHDC than in AOT. Meanwhile, in the quenching by the hydrophobic tributylamine (TBA) the decay is mono-exponential. The amine is located preferentially in the bulk organic phase and the quenching mechanism involves the interaction of the amine with the monoprotonated triplet of dye reaching in the micellar interface. It is interesting to note that the apparent quenching rate constant by TBA is one order of magnitude lower than the exchange rate constant by TEOA. This study involved multiple reactions and reactants, such as N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9HPLC of Formula: 122-18-9).

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. Chlorination modifies the physical properties of hydrocarbons in several ways. These compounds are typically denser than water due to the higher atomic weight of chlorine versus hydrogen. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.HPLC of Formula: 122-18-9

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics