Category: 122-18-9

Determination of Benzyl-hexadecyldimethylammonium 1,4-Bis(2-ethylhexyl)sulfosuccinate Vesicle Permeability by Using Square Wave Voltammetry and an Enzymatic Reaction was written by Cobo Solis, Airam K.;Correa, N. Mariano;Molina, Patricia G.. And the article was included in Langmuir in 2017.HPLC of Formula: 122-18-9 The following contents are mentioned in the article:

This report describes the studies performed to determine the permeability coefficient value (P) of 1-naphthyl phosphate (1-NP) through the benzyl-hexadecyldimethylammonium 1,4-bis(2-ethylhexyl)sulfosuccinate (AOT-BHD) vesicle bilayer. 1-NP was added in the external phase and must cross the bilayer of the vesicle to react with the encapsulated enzyme (alk. phosphatase) to yield 1-naphtholate (NPh^–), the product of the enzymic hydrolysis. This product is electrochem. detected, at basic pH value, by a square wave voltammetry technique, which can be a good alternative over the spectroscopic one, to measure the vesicle solutions because scattering (due to its turbidity) does not have any influence in the electrochem. signal. The exptl. data allow the authors to propose a math. model, and a value of P = (1.00 ± 0.15) × 10^-9 cm s^-1 was obtained. Also, a value of P = (2.0 ± 0.5) × 10^-9 cm s^-1 was found by using an independent technique, UV-visible spectroscopy, for comparison. It is evident that the P values obtained from both the techniques are comparable (within the exptl. error of both techniques) under the same exptl. conditions. This study constitutes the first report of the 1-NP permeability determination in this new vesicle. The authors want to highlight the importance of the introduction of a new method and the electrochem. response of the product generated through an enzymic reaction that occurs in the inner aqueous phase of the vesicle, where the enzyme is placed. This study involved multiple reactions and reactants, such as N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9HPLC of Formula: 122-18-9).

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. Organochlorines stimulate the central nervous system and cause convulsions, tremor, nausea, and mental confusion. Examples are dichlorodiphenyltrichloroethane (DDT), chlordane, lindane, endosulfan, and dieldrin. Organochlorine compounds are lipophylic, meaning they are more soluble in fat than in water. This gives them a high tenancy to accumulate in the food chain (biomagnification).HPLC of Formula: 122-18-9

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Application of an algal growth inhibition assay to determine distribution coefficients of benzalkonium ions between kaolinite and water was written by Ndabambi, Mlamuli;Kwon, Jung-Hwan. And the article was included in Ecotoxicology and Environmental Safety in 2019.Electric Literature of C25H46ClN The following contents are mentioned in the article:

Benzalkonium compounds are widely used and found in environmental samples. Due to their amphiphilic nature, it is important to know sorption coefficients to account their bioavailability. However, currently available models describing their partitioning were developed using low mol. weight homologues and it cannot be ascertained whether they are applicable to their higher mol. weight homologues. Reasons for the scarcity of data on highly sorptive compounds include the lack of reliable quantification techniques for analyzing these chems. at environmentally relevant levels. This study, therefore, reports on an algal growth inhibition assay-based method for the determination of kaolinite/water distribution coefficients for benzalkonium compounds at their environmentally relevant concentration range. Sorption to clay was computed using the difference between median effective concentration determined in a culture with kaolinite and that derived from a culture grown in standard medium. A kinetic model was used to account for uptake into algal cells and to calculate free concentrations Due to the sensitivity of the algal species, Pseudokirchneriella subcapitata, it was possible to determine distribution coefficients below micromole per L concentrations The computed distribution coefficients showed a linear increase with number of carbon atoms in the alkyl chain up to 14. The proposed bioassay-based method should be applicable to determine distribution coefficients for highly hydrophobic chems. and ionic liquids at a concentration range lower than typical anal. limits. This study involved multiple reactions and reactants, such as N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9Electric Literature of C25H46ClN).

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. Alkyl chlorides readily react with amines to give substituted amines. Alkyl chlorides are substituted by softer halides such as the iodide in the Finkelstein reaction.Electric Literature of C25H46ClN

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Fast detection of benzalkonium chloride in eye drops based on nano electrospray-portable ion trap mass spectrometry was written by Zha, Yue;Shen, Xuejing;Li, Ming. And the article was included in Fenxi Shiyanshi in 2021.Computed Properties of C25H46ClN The following contents are mentioned in the article:

In this work, a rapid detection method without using chromatog. for the determination of bactericidal component of benzalkonium chloride in com. eye drops was established by building a nanoelectrospray ionization (Nano-ESI) with portable ion trap mass spectrometer (Ion Trap MS). In the pos. ion mode, the eye drops sample was diluted and injected into the capillary for rapid qual. and quant. anal. The optimal anal. conditions were obtained as follows, the distance between the capillary outlet and the injection port was 10 mm, and the spray voltage was 2000 V, the capillary voltage, capillary temperature and ion funnel voltage were set at 5 V, 30°C and 40 V, resp. The [M-Cl]⁺ peaks of three benzalkonium chlorides were used as qual. criteria, and the solution was prepared with pure substance and then analyzed by quant. anal. of standard curves. Under the optimized conditions, the linear range of the three components in the diluted eye drops was 1-500 mg/L with good correlation coefficient (R²> 0.99). The limit of detection (LOD) of the method evaluated by 11 blank sample test results was 0.1 mg/L and the limit of quantification (LQD) was 0.33 mg/L. Compared with the ultrahigh performance liquid chromatog. (UPLC)-MS method, there was no significant difference between the quant. determination results for the actual samples, but the anal. time of the Nano-ESI MS method was shorter (2 min). Therefore, the method can be used for rapid screening and quant. determination of benzalkonium chloride as an additive in eye drops. This study involved multiple reactions and reactants, such as N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9Computed Properties of C25H46ClN).

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. Organochlorine compounds are lipophylic, meaning they are more soluble in fat than in water. This gives them a high tenancy to accumulate in the food chain (biomagnification).Computed Properties of C25H46ClN

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Facile Synthesis of Concave Cuboid Au NCs with Precisely Tunable Dimensions and Mechanistic Insight was written by Rajendra, Ranguwar;Roy, Debashree;Tripathi, Shalini;Ballav, Nirmalya. And the article was included in Langmuir in 2019.Computed Properties of C25H46ClN The following contents are mentioned in the article:

Concave cuboid (CCB) nanostructure is a member of the high-index facet (HIF) nanocrystals (NCs) family, geometrically derived from regular cuboid-excavation of each face. CCB NCs hold some addnl. characteristics such as surface cavity and sharp edges and corners as compared to its convex counterpart that makes it relatively more active in applications like electrochem. catalysis, surface enhanced Raman spectroscopy (SERS), and plasmonics. To date, there are only few reports available on the synthesis of CCB Au NCs where Br^– containing surfactants have been used as a shape directing and stabilizing agent. However, none of them led to decent yield and size tunability. Herein, we report a robust seed mediated growth strategy where cetyltrimethylammonium chloride (CTAC) and tannic acid (TA) have been used as shape-directing/stabilizing and mild reducing agents, resp. Our method not only allows the high yield fabrication of CCB Au NCs with uniform shape and size but also precise control over dimensions and degree of surface concavity. Moreover, the investigation of growth mechanism revealed that the evolution of CCB Au NCs from cylindrical nanorods (NRs) take place via arrow-headed nanorods and truncated CCB nanostructures. Furthermore, it has been observed that the presence of excess of Cl^– is indeed playing a decisive role despite the headgroup of counter cationic part of surfactant. We anticipate that our findings may pave the path to design new synthetic strategies and understand the evolution of new nanostructures. This study involved multiple reactions and reactants, such as N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9Computed Properties of C25H46ClN).

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst.Computed Properties of C25H46ClN

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

A fast and robust method for the extraction and analysis of quaternary alkyl ammonium compounds from soil and sewage sludge was written by Heyde, Benjamin Justus;Barthel, Anne;Siemens, Jan;Mulder, Ines. And the article was included in PLoS One in 2020.Product Details of 122-18-9 The following contents are mentioned in the article:

Alkyltrimethylammonium compounds (ATMACs), dialkyldimethylammonium compounds (DADMACs) and benzylalkyldimethylethylammonium compounds (BACs) are quaternary alkylammonium compounds (QAAC), which are released into the environment in large quantities after their use in cleaning agents and disinfectants. Despite their potential role as selective agents promoting resistance against QAACs as well as antibiotics, there is a lack of data for QAACs in soil due to the lack of sensitive anal. methods. Therefore, we present a robust and fast method for the extraction and quantification of concentrations of these compounds in soil and sewage sludge. The method is based on ultrasonic extraction (USE) with a mixture of acetonitrile and HCl followed by a solid phase extraction (SPE) cleaning step and a subsequent quantification of concentrations with high performance liquid chromatog. with mass spectrometry (HPLC-MS/MS) in multi mass reaction mode (MRM). The proposed method is suitable for the quantification of ATMACs (chain length C-8 to C-16), BACs (C-8 to C-18) and DADMACs (C-8 to C-16). The achieved limits of quantification (LOQ) range from 0.1μg kg-1 to 2.1μg kg-1. The recovery rates of spiked soil samples for non-deuterated homologues were between 47% and 57%. The anal. of sewage sludge samples and soil samples revealed that BAC-C12 was the most abundant QAAC with concentrations up to 38600μg kg-1 in sewage sludge and up to 81μg kg-1 in a Mexican soil that was irrigated with wastewater. Overall, the presented methods open perspectives for effectively studying fate and effects of QAACs in soils. This study involved multiple reactions and reactants, such as N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9Product Details of 122-18-9).

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. The hydrocarbon processing industry (HPI) and others are affected by damage caused by these substances. Organochlorine compounds are lipophylic, meaning they are more soluble in fat than in water. This gives them a high tenancy to accumulate in the food chain (biomagnification).Product Details of 122-18-9

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Synthesis, aggregation and adsorption behavior of benzyldimethylhexadecylammonium based double-chained metallosurfactants was written by Wagay, Tariq Ahmad;Askari, Hassan;Ismail, K.. And the article was included in Journal of Molecular Liquids in 2020.Safety of N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride The following contents are mentioned in the article:

Benzyldimethylhexadecylammonium (BDHA) based double-chained metallosurfactants, BDHA₂[MCl₄] (M = Mn, Co, Ni, Cu, Zn) were synthesized and characterized by elemental anal., NMR (¹H, ¹³C) and FT-IR spectroscopy. Thermal gravimetric anal. showed more stability of synthesized metallosurfactants as compared to the precursor benzyldimethylhexadecylammonium chloride. Their critical micelle concentration (cmc) values were determined in aqueous medium by using surface tension, conductivity and fluorescence spectrophotometric methods. The cmc values follow the order: Mn > Co ≈ Cu ≈ Zn > Ni. The thermodn. parameters of micellization were computed from the temperature dependence of the cmc. These metallosurfactants have surprisingly low counterion binding constant values (0.25 to 0.31) compared to benzyldimethylhexadecylammonium chloride and other ionic surfactants. Compensation of enthalpy and entropy of micellization of BDHA₂[MCl₄] metallosurfactants is observed in the aqueous medium. Adsorption behavior of BDHA₂[MCl₄] metallosurfactants was assessed by calculating surface excess and area per mol. at the air/water interface. Dynamic light scattering and zeta potential measurements revealed the small average hydrodynamic diameter of highly stable micelles of the metallosurfactants in aqueous solutions (hydrodynamic diameter = 4-6 nm with polydispersity index <0.13 and zeta potential >+45 mV). Transmission electron microscope measurements also showed the presence of small spherical micelles. This study involved multiple reactions and reactants, such as N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9Safety of N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride).

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. Organochlorines stimulate the central nervous system and cause convulsions, tremor, nausea, and mental confusion. Examples are dichlorodiphenyltrichloroethane (DDT), chlordane, lindane, endosulfan, and dieldrin. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.Safety of N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Responses of anaerobic digestion of waste activated sludge to long-term stress of benzalkonium chlorides: Insights to extracellular polymeric substances and microbial communities was written by He, Zhang-Wei;Liu, Wen-Zong;Tang, Cong-Cong;Liang, Bin;Zhou, Ai-Juan;Chen, Fan;Ren, Yong-Xiang;Wang, Ai-Jie. And the article was included in Science of the Total Environment in 2021.Application of 122-18-9 The following contents are mentioned in the article:

Quaternary ammonium compounds have gained widespread attention due to their extensive enrichment in waste activated sludge (WAS) and potentially adverse effect to anaerobes. This study selected benzalkonium chlorides (BACs) as model to reveal the responses of anaerobic digestion of WAS to long-term stress of BACs. Results showed that the solubilization enhancement of WAS contributed by BACs was the acceleration of cell lysis, rather than the disruption of extracellular polymeric substances, and the accumulation improvement of short chain fatty acids (SCFAs) attributed to hydrolysis improvement and methanogenesis inhibition at either medium -or high level of BACs. In addition, a low level had no significant effect on the production of methane compared to control, with averages of 0.059 and 0.055 m3/(m3·d), resp., whereas a medium level reduced methane production to 20% of control, and a high level almost completely inhibited methanogenesis. Correspondingly, BACs could shift microbial communities related to SCFAs and methane productions. For the bacterial community, a high level of BACs led to abundance reductions of Firmicutes, Bacteroidetes, Acidobacteria and Chloroflexi, but Synergistetes was increased to 10.5%, which was almost not detected either in control or at a low level of BACs. And for dominant archaeal community, they tended to be shifted from acetotrophic to hydrogenotrophic methanogens with BACs increasing from low to high level. These findings provided some new insights for the role of BACs in anaerobic digestion, as well as resource recovery from WAS. This study involved multiple reactions and reactants, such as N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9Application of 122-18-9).

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. Alkyl chlorides readily react with amines to give substituted amines. Alkyl chlorides are substituted by softer halides such as the iodide in the Finkelstein reaction.Application of 122-18-9

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Fabrication of Polydiacetylene Liposome Chemosensor with Enhanced Fluorescent Self-Amplification and Its Application for Selective Detection of Cationic Surfactants was written by Wang, Dong-En;Zhao, Lei;Yuan, Mao-Sen;Chen, Shu-Wei;Li, Tianbao;Wang, Jinyi. And the article was included in ACS Applied Materials & Interfaces in 2016.HPLC of Formula: 122-18-9 The following contents are mentioned in the article:

Polydiacetylene (PDA) materials have been adopted as one of the powerful conjugated polymers for sensing applications due to their unique optical properties. In this paper, we present a new PDA liposome-based sensor system with enhanced fluorescent self-amplification by tuning a fluorophore fluorescence emission. In this system, a 1,8-naphthalimide derivative employed as a highly fluorescent fluorophore was incorporated into a PDA supermol. During the formation of blue PDA liposomes, the fluorescence emission of the fluorophore can be directly quenched, while thermal-induced phase transition of PDA liposomes from blue to red can readily restore this fluorescence emission. These phenomena could be ascribed to the tunable Forster energy transfer between the excited fluorophore and PDA conjugated framework. To demonstrate the sensing performance of this newly prepared PDA liposome-based sensor, the sensor with fluorescent self-amplification was successfully applied for the detection of cationic surfactants (CS). The results show that the PDA liposomes displayed a distinct color change and fluorescence restoration in the presence of cationic surfactant species, and allowed detection of cationic surfactants with high sensitivity and selectivity. The limit of detection for target CS, such as cetyltrimethylammonium bromide (CTAB), can reach as low as 184 nM. Compared to the traditional methods based on colorimetric PDA liposomes, this newly fabricated PDA sensor system was superior for sensitivity. Thus, our findings offer an avenue for the design and development of new types of PDA sensors with enhanced sensitivity. This study involved multiple reactions and reactants, such as N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9HPLC of Formula: 122-18-9).

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. An organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control.HPLC of Formula: 122-18-9

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Interaction between tetradecyltrimethylammonium bromide and benzyldimethylhexadecylammonium chloride in aqueous/urea solution at various temperatures: An experimental and theoretical investigation was written by Molla, Mohammad Robel;Abdul Rub, Malik;Ahmed, Anwar;Hoque, Anamul Md.. And the article was included in Journal of Molecular Liquids in 2017.Formula: C25H46ClN The following contents are mentioned in the article:

The mixed micelle formation between tetradecyltrimethylammonium bromide (TTAB) and benzyldimethylhexadecylammonium chloride (BDHAC) has been investigated in the absence as well as attendance of urea using conductivity technique. The evaluated values were examined in accordance with Rubingh model. The obtained values of critical micelle concentration (cmc) were smaller than cmc^id values suggesting attractive interactions between the constituents of solution The micellar mole fractions (X^Rub₁) of BDHAC, estimated by Rubingh model, were always higher than their ideal values (X^id₁) suggesting the high contributions of BDHAC in mixtures of TTAB and BDHAC. Interaction parameter (β) value was found to be neg. showing an attractive interaction between the studied components. Activity coefficients (f^Rub₁ and f^Rub₂) were always smaller than one in all cases and it indicates the attractive interaction between TTAB and BDHAC. The values of ΔG^o_m are found to be neg. in all the cases which indicate the spontaneous formation of micelle. The values of ΔH⁰_m are neg. in all cases indicating the exothermic process. The values of ΔS⁰_m are pos. in case of aqueous medium and 500 mmol·kg^– 1 urea solutions but found to be neg. in attendance of 1000 mmol·kg^– 1 urea. The values of excess free energy of micellization (ΔG^Rub_ex) were also estimated and achieved to be neg. showing the stability of mixed micelles. This study involved multiple reactions and reactants, such as N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9Formula: C25H46ClN).

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. Organic chlorides can be used in production of: PVC, pesticides, chloromethane, teflon, insulators.While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.Formula: C25H46ClN

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Cationic nanoemulsions with prolonged retention time as promising carriers for ophthalmic delivery of tacrolimus was written by Zhang, Jialiang;Liu, Zhihong;Tao, Chun;Lin, Xin;Zhang, Minxin;Zeng, Lingjun;Chen, Xu;Song, Hongtao. And the article was included in European Journal of Pharmaceutical Sciences.Recommanded Product: N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride The following contents are mentioned in the article:

Tacrolimus, also known as FK506, is a first-line drug for the topical treatment of immune-mediated inflammatory anterior ocular diseases (IIAODs). However, due to its limited water solubility, hydrophobic nature and relatively high mol. weight, topical application of FK506 features poor bioavailability. Numbers of formulations have been attempted to enhance the erratic bioavailability of FK506 through various techniques. But until now, none of them could satisfy the clin. needs completely. Here, a novel formulation of FK506, FK506-loaded cationic nanoemulsions (FK506 CNE), was developed to prolong the precorneal residence time of FK506, thereby enhancing the bioavailability of FK506 for IIAODs therapy. FK506 CNE was prepared by high-pressure homogenization, and its composition was screened and optimized by single-factor experiments The FK506 CNE showed spherical morphol. with a mean diameter of 178.8 ± 2.7 nm and a zeta potential of +25.6 ± 0.6 mV. Results from in vivo gamma scintigraphy studies proved that the precorneal residence time of FK506 CNE was significantly increased, compared with FK506-loaded neutral nanoemulsions (FK506 NE) and saline. The data of aqueous humor pharmacokinetic study in rabbits showed that the relative bioavailability of FK506 CNE was 1.68-fold and 1.77-fold of FK506 NE and the marketed FK506 eye drops (Talymus), resp. Finally, hematoxylin and eosin staining images and in vitro cytotoxicity data confirmed the safety of the FK506 CNE. Taking all these into consideration, we propose that FK506 CNE is a promising topical ophthalmic nanoformulation for the management of IIAODs. This study involved multiple reactions and reactants, such as N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9Recommanded Product: N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride).

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.Recommanded Product: N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics