Category: 1186603-47-3

Metal-free benzannulation of 1,7-diynes towards unexpected 1-aroyl-2-naphthaldehydes and their application in fused aza-heterocyclic synthesis was written by Wang, Ai-Fang;Zhou, Peng;Zhu, Yi-Long;Hao, Wen-Juan;Li, Guigen;Tu, Shu-Jiang;Jiang, Bo. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2017.HPLC of Formula: 1186603-47-3 The following contents are mentioned in the article:

A novel I₂-mediated benzannulation of 1,7-diyne involving 1,4-oxo-migration was established, providing a range of unexpected 1-aroyl-2-naphthaldehydes with a 1,4-dicarbonyl unit [e.g., I → II (72%) in presence of I₂, H₂O and O₂ in MeCN]. The resulting 1-aroyl-2-naphthaldehydes were successfully applied in the synthesis of benzo[e]isoindol-3-ones and benzo[e]benzo[4,5]imidazo[2,1-a]isoindoles using aromatic amines and benzene-1,2-diamines as nucleophiles, resp. The mechanisms for the formation of these compounds were proposed. This study involved multiple reactions and reactants, such as 5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3HPLC of Formula: 1186603-47-3).

5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.HPLC of Formula: 1186603-47-3

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Synthesis of selenated tetracyclic indoloazulenes via iodine and diorganyl diselenides was written by Win, Khin Myat Noe;Sonawane, Amol D.;Koketsu, Mamoru. And the article was included in Organic & Biomolecular Chemistry in 2021.Reference of 1186603-47-3 The following contents are mentioned in the article:

An efficient protocol for the synthesis of selenated tetracyclic indoloazulenes I (R = H, Me, F; R¹ = Me, n-Pr, n-Bu, Ph; R² = H, OMe; R³ = H, OMe, Cl) was reported. The reaction of diorganyl diselenides R¹SeSeR¹ with mol. iodine in dichloromethane leads to the in situ formation of organo selenenyl iodide. The synthesis of selenylated tetracyclic indoloazulenes I through intramol. cascade cyclization has been achieved via organo selenenyl iodide and bisindole at room temperature under metal-free conditions in good yields. This study involved multiple reactions and reactants, such as 5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3Reference of 1186603-47-3).

5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control.Reference of 1186603-47-3

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Merging [2+2] Cycloaddition with Radical 1,4-Addition: Metal-Free Access to Functionalized Cyclobuta[a]naphthalen-4-ols was written by Liu, Feng;Wang, Jia-Yin;Zhou, Peng;Li, Guigen;Hao, Wen-Juan;Tu, Shu-Jiang;Jiang, Bo. And the article was included in Angewandte Chemie, International Edition in 2017.Computed Properties of C15H9ClO The following contents are mentioned in the article:

A metal-free [2+2] cycloaddition and 1,4-addition sequence induced by S-centered radicals has been achieved by treating benzene-linked allene-ynes with aryldiazonium tetrafluoroborates and DABCO-bis(sulfur dioxide) in a one-pot procedure. The reaction provides a greener and more practical access to functionalized cyclobuta[a]naphthalen-4-ols with valuable applications. More than 50 examples are demonstrated with excellent diastereoselectivity and chem. yields. The reaction pathway is proposed to proceed by the following steps:[2+2] cycloaddition, insertion of SO₂, 1,4-addition, diazotization, and tautomerization. This study involved multiple reactions and reactants, such as 5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3Computed Properties of C15H9ClO).

5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.Computed Properties of C15H9ClO

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

A concise synthesis of 10-benzoyl-3,4-dihydroanthracen-1(2H)-one derivatives catalyzed by TfOH under metal-free conditions was written by Wu, Hao;Chen, Hua-Dong;Liu, Jian-Quan;Li, Qiu-Yan;Wang, Xiang-Shan. And the article was included in Synthetic Communications in 2021.Product Details of 1186603-47-3 The following contents are mentioned in the article:

TfOH was proved to be an efficient catalyst to promote the intra-mol. cyclization, Diels-Alder reaction, deprotonation and dehydration and provided a synthesis of 10-benzoyl-3,4-dihydroanthracen-1(2H)-ones I [R = Ph, 4-FC₆H₄, 4-EtC₆H₄, etc.; R¹ = H, 7-F, 6-Cl, etc.; R² = H; R³ = Ph; R² = R³ = Me; R⁴ = H, Me] in good yields from a reaction of 2-(phenylethynyl) benzaldehyde and cyclohexane-1,3-dione. It underwent in high regioselectivity when center asym. 4,4-dimethylcyclohexane-1,3-dione was used as a reactant. This study involved multiple reactions and reactants, such as 5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3Product Details of 1186603-47-3).

5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3) belongs to organic chlorides. Organochlorines stimulate the central nervous system and cause convulsions, tremor, nausea, and mental confusion. Examples are dichlorodiphenyltrichloroethane (DDT), chlordane, lindane, endosulfan, and dieldrin. Organochlorine compounds are lipophylic, meaning they are more soluble in fat than in water. This gives them a high tenancy to accumulate in the food chain (biomagnification).Product Details of 1186603-47-3

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Gold-Catalyzed One-Pot A³-Coupling/1,5-Hydride Shift/Schmittel-Type Cyclization: From Aldehydes, Amines and Alkynes to the Synthesis of Benzo[b]fluorenes was written by Lustosa, Danilo M.;Hartmann, Deborah;Rudolph, Matthias;Rominger, Frank;Hashmi, A. Stephen K.. And the article was included in European Journal of Organic Chemistry in 2020.Related Products of 1186603-47-3 The following contents are mentioned in the article:

A step-economic gold-catalyzed one-pot synthesis of benzo[b]fluorenes was described from aldehydes, alkynes and amines via an A³-coupling/1,5-hydride shift/Schmittel-type cyclization. The formation of the allene intermediate was not dependent on a previous installation of reaction triggers and upon cyclization delivered benzo[b]fluorenes. With this method, just by an easy modification of the starting materials in a modular way, nineteen benzo[b]fluorenes bearing different substituents Ar¹, Ar² and Ar³, were prepared Overall, three new carbon-carbon bonds were formed in one-pot. This study involved multiple reactions and reactants, such as 5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3Related Products of 1186603-47-3).

5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. Alkyl chlorides are versatile building blocks in organic chemistry. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available.Related Products of 1186603-47-3

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Gold-Catalyzed Reaction of ortho-Alkynylarylaldehydes with Conjugated Dienes: An Efficient Access to Highly Strained Tetracyclic Bridgehead Olefins was written by Cao, Ziping;Zhu, Hongbo;Meng, Xin;Tian, Laijin;Sun, Xuejun;Chen, Guang;You, Jinmao. And the article was included in Chemistry – A European Journal in 2016.Formula: C15H9ClO The following contents are mentioned in the article:

An unprecedented access to strained tetracyclic bridgehead alkenes by reaction of easily accessible ortho-alkynylarylaldehydes with conjugated dienes was described. The process involved a chemo- and stereo-selective, gold-catalyzed, tandem intermol. [3+2] cycloaddition/Prins-type ring-closing reaction that allowed generating structural complexity in a straightforward manner. This approach for the preparation of anti-Bredt compounds was synthetically superior to those previously reported: the procedure was easy to implement, operates under mild exptl. conditions, was efficient, and exhibited a good substrate scope. This study involved multiple reactions and reactants, such as 5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3Formula: C15H9ClO).

5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3) belongs to organic chlorides. An organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.Formula: C15H9ClO

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Visible light amination/Smiles cascade: access to phthalazine derivatives was written by Brachet, Etienne;Marzo, Leyre;Selkti, Mohamed;Konig, Burkhard;Belmont, Philippe. And the article was included in Chemical Science in 2016.Recommanded Product: 1186603-47-3 The following contents are mentioned in the article:

The synthesis of various phthalazines via a new cascade reaction, initiated by visible light photocatalysis, involving a radical hydroamination reaction followed by a radical Smiles rearrangement is reported. Phthalazine derivatives are obtained in high yields and from a broad scope readily accessible ortho-alkynylsulfonohydrazone precursors. The mild photoredox conditions ensure an excellent functional group tolerance. Application of this strategy to a one-pot protocol starting from the corresponding carbonyl compounds, and subsequent functionalization allow the rapid synthesis of structurally diverse structures. This study involved multiple reactions and reactants, such as 5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3Recommanded Product: 1186603-47-3).

5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.Recommanded Product: 1186603-47-3

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Catalytic Asymmetric Three-Component Reaction of 2-Alkynylbenzaldehydes, Amines and Dimethylphosphonate was written by Zou, Liangliang;Huang, Jiaying;Liao, Na;Liu, Yan;Guo, Qixiang;Peng, Yungui. And the article was included in Organic Letters in 2020.Related Products of 1186603-47-3 The following contents are mentioned in the article:

An efficient enantioselective synthesis of cyclic α-aminophosphonates via multicomponent reactions of 2-alkynylbenzaldehydes, amines and dimethylphosphonate has been developed with the use of a chiral silver spirocyclic phosphate as the catalyst. This protocol provides straightforward access to a series of chiral C1-phosphonylated 1,2-dihydroisoquinoline derivatives, e.g. I, with high yields (up to 99%) and high enantioselectivities (up to 94% ee) for a broad substrate scope. The products could be further transformed into densely functionalized compounds and corresponding α-aminophosphonic acids. This study involved multiple reactions and reactants, such as 5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3Related Products of 1186603-47-3).

5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3) belongs to organic chlorides. Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. The hydrocarbon processing industry (HPI) and others are affected by damage caused by these substances. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.Related Products of 1186603-47-3

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Synthesis of thienyl-substituted isochromene derivatives through gold-catalyzed tandem heteroarylation/cycloisomerization of ortho-alkynylbenzaldehydes with thiophenes was written by Zhu, Hongbo;Meng, Xin;Cao, Ziping;Chen, Guang;Sun, Xuejun;You, Jinmao. And the article was included in Synthetic Communications in 2017.Electric Literature of C15H9ClO The following contents are mentioned in the article:

A gold-catalyzed tandem heteroarylation/cycloisomerization reaction of ortho-alkynylbenzaldehydes with thiophenes was described. By this reaction, a variety of 1-(thiophen-2-yl)-1H-isochromene derivatives were obtained in good yield. This study involved multiple reactions and reactants, such as 5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3Electric Literature of C15H9ClO).

5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3) belongs to organic chlorides. An organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. Organochlorine compounds are lipophylic, meaning they are more soluble in fat than in water. This gives them a high tenancy to accumulate in the food chain (biomagnification).Electric Literature of C15H9ClO

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

An Unexpected Silver Triflate Catalyzed Reaction of 2-Alkynylbenzaldehyde with 2-Isocyanoacetate was written by Zheng, Danqing;Li, Shaoyu;Wu, Jie. And the article was included in Organic Letters in 2012.Application of 1186603-47-3 The following contents are mentioned in the article:

An unexpected silver triflate catalyzed reaction of 2-alkynylbenzaldehyde with 2-isocyanoacetate provides an efficient route for the generation of isoquinolines. The reaction proceeds smoothly in air under mild conditions with high efficiency. This study involved multiple reactions and reactants, such as 5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3Application of 1186603-47-3).

5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3) belongs to organic chlorides. Chlorination modifies the physical properties of hydrocarbons in several ways. These compounds are typically denser than water due to the higher atomic weight of chlorine versus hydrogen. Organochlorine compounds are lipophylic, meaning they are more soluble in fat than in water. This gives them a high tenancy to accumulate in the food chain (biomagnification).Application of 1186603-47-3

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics