Category: 1186603-47-3

Visible-Light Photocatalytic Bicyclization of 1,7-Enynes toward Functionalized Sulfone-Containing Benzo[a]fluoren-5-ones was written by Huang, Min-Hua;Zhu, Yi-Long;Hao, Wen-Juan;Wang, Ai-Fang;Wang, De-Cai;Liu, Feng;Wei, Ping;Tu, Shu-Jiang;Jiang, Bo. And the article was included in Advanced Synthesis & Catalysis in 2017.Product Details of 1186603-47-3 The following contents are mentioned in the article:

A new visible-light photocatalytic arylsulfonylation and bicyclization of C(sp³)-tethered 1,7-enynes with sulfinic acids has been developed, delivering functionalized sulfone-containing benzo[a]fluoren-5-ones, e.g., I with generally good yields. This eosin Y-catalyzed approach makes use of visible light as a safe and eco-friendly energy source to drive cascade cyclization reactions, resulting in continuous multiple bond-forming events including C-S and C-C bonds to efficiently construct polycyclic-linked alkyl aryl sulfones. This study involved multiple reactions and reactants, such as 5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3Product Details of 1186603-47-3).

5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3) belongs to organic chlorides. Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. The hydrocarbon processing industry (HPI) and others are affected by damage caused by these substances. Alkyl chlorides readily react with amines to give substituted amines. Alkyl chlorides are substituted by softer halides such as the iodide in the Finkelstein reaction.Product Details of 1186603-47-3

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Visible light-assisted Ni-/Ir-catalysed atom-economic synthesis of spiro[furan-3,1′-indene] derivatives was written by Gore, Babasaheb Sopan;Kuo, Chiao-Ying;Wang, Jeh-Jeng. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2022.Computed Properties of C15H9ClO The following contents are mentioned in the article:

An atom-economic, efficient, and highly convenient construction of spiro[furan-3,1′-indene] skeletons from isocyanides and 1,5-enynes by synergistic nickel- and iridium-photocatalysis is reported. Spirocyclization was developed under practical and mild conditions, which features excellent functional group tolerance, gram-scale synthesis and representative synthetic transformations for the obtained products and broad substrate scope. Primary mechanistic studies demonstrated that the reaction proceeds through energy-transfer-mediated excitation of intermediate catalytic species. This study involved multiple reactions and reactants, such as 5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3Computed Properties of C15H9ClO).

5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.Computed Properties of C15H9ClO

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Gold-Catalyzed Bicyclic Annulations of 2-Alkynylbenzaldehydes with Vinyldiazo Carbonyls that Serve as Five-atom Building Units was written by Raj, Antony Sekar Kulandai;Liu, Rai-Shung. And the article was included in Angewandte Chemie, International Edition in 2019.Synthetic Route of C15H9ClO The following contents are mentioned in the article:

In the presence of (PhO)₃PAuCl and AgOTf, α-diazo-β,γ-unsaturated ketones such as H₂C:CHC(:N₂)COPh underwent diastereoselective cyclization reactions with ortho-alkynylbenzaldehydes such as 2-(phenylethynyl)benzaldehyde to yield tetrahydrobenzindazoles such as I in which five atoms of the diazo compound are incorporated into the product. Mechanistic experiments provided evidence for a mechanism involving the initial [5+4]-cycloaddition of a benzopyrylium intermediate and a vinyldiazoketone followed by 6π-electrocyclization. This study involved multiple reactions and reactants, such as 5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3Synthetic Route of C15H9ClO).

5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.Synthetic Route of C15H9ClO

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Highly Selective Construction of Medium-Sized Lactams by Palladium-Catalyzed Intramolecular Hydroaminocarbonylation of Aminoalkynes was written by Hu, Yue;Huang, Hanmin. And the article was included in Organic Letters in 2017.HPLC of Formula: 1186603-47-3 The following contents are mentioned in the article:

In the presence of Pd(cod)Cl₂ and Ph₂P(CH₂)_nPPh₂ (n = 4, 6) in anisole at 80°, alkynylamines such as I underwent chemoselective and regioselective carbonylative hydroamination reactions to yield seven- and eight-membered lactams such as dihydrobenzazepinone II in 41-99% yields. The structures of II, of three other dihydrobenzazepinones, of a dihydronaphthazepinone, of a dihydroazepinone, and of a dihydrobenzazocinone were determined by X-ray crystallog. This study involved multiple reactions and reactants, such as 5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3HPLC of Formula: 1186603-47-3).

5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.HPLC of Formula: 1186603-47-3

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Oxaziridine-mediated intramolecular amination of sp³-hybridized C-H bonds was written by Allen, Charles P.;Benkovics, Tamas;Turek, Amanda K.;Yoon, Tehshik P.. And the article was included in Journal of the American Chemical Society in 2009.SDS of cas: 1186603-47-3 The following contents are mentioned in the article:

We describe a new oxaziridine-mediated approach to the amination of sp³-hybridized C-H bonds. In the presence of a copper(II) catalyst, N-sulfonyl oxaziridines participate in efficient intramol. cyclization reactions to afford a variety of piperidine and tetrahydroisoquinoline structures, e.g. I and II. The aminal intermediates provide a convenient functional handle for further elaboration of these structures, demonstrating the utility of this new methodol. for the rapid construction of structurally complex nitrogen-containing heterocycles. This study involved multiple reactions and reactants, such as 5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3SDS of cas: 1186603-47-3).

5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3) belongs to organic chlorides. Organic chlorides can be used in production of: PVC, pesticides, chloromethane, teflon, insulators.While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.SDS of cas: 1186603-47-3

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Cascade bicyclizations of o-alkynyl aldehydes with thiazolium salts: a new access toward poly-functionalized indeno[2,1-b]pyrroles was written by Zhou, Peng;Hao, Wen-Juan;Zhang, Jin-Peng;Jiang, Bo;Li, Guigen;Tu, Shu-Jiang. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2015.Computed Properties of C15H9ClO The following contents are mentioned in the article:

A new cascade bicyclization of o-alkynyl aldehydes with thiazolium salts is described, in which 25 examples of densely functionalized indeno[2,1-b]pyrroles I (Z = CH, N; R = Et, Me, Bn; R¹ = H, 6-F, 6-Cl, 5-F; Ar = Ph, 4-MePh, 4-OMePh, 4-FPh, 4-ClPh, etc.) are achieved in a functional-group-compatible manner. Thiazole carbenes generated in situ from thiazolium salts play dual roles as reaction partners and as NHC catalysts. The synthetic utility of these bicyclization reactions results in subsequent C-C bond-forming events to rapidly build up mol. complexity. This study involved multiple reactions and reactants, such as 5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3Computed Properties of C15H9ClO).

5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3) belongs to organic chlorides. Organochlorines are organic compounds having multiple chlorine atoms. They were the first synthetic pesticides that were used in agriculture. They are resistant to most microbial and chemical degradations. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.Computed Properties of C15H9ClO

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Silver Nitrate Mediated Cyclization/N-N Bond-Cleavage Reaction for the Synthesis of 3-Arylisoquinolines was written by Zhao, Yun-Hui;Li, Yubo;Luo, Mingjian;Tang, Zilong;Deng, Keqin. And the article was included in Synlett in 2016.Name: 5-Chloro-2-(phenylethynyl)benzaldehyde The following contents are mentioned in the article:

An unprecedented silver nitrate mediated novel transformation of aromatic hydrazones (R¹)(2-H₂NN=C)C₆H₃CCR² (R¹ = H, 4-Cl, 5-F, 4-Me, 4-MeO; R² = C₆H₅, 4-ClC₆H₄, 4-H₃COC₆H₄, etc.) into various isoquinolines I (X = H, 6-F, 7-Cl, 7-Me, 7-MeO) has been developed. This method involves a silver nitrate promoted cyclization of aromatic hydrazones followed by N-N bond cleavage, and has wide substrate scope under mild conditions. This study involved multiple reactions and reactants, such as 5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3Name: 5-Chloro-2-(phenylethynyl)benzaldehyde).

5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.Name: 5-Chloro-2-(phenylethynyl)benzaldehyde

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Metal-/solvent-free oxidative [4 + 2]/[3 + 2] annulation of 2-ethynylbenzaldehydes with arylalkenes: facile synthesis of benzo[a]fluoren-5-ones was written by Wang, Cheng-Yong;Yu, Jiang-Xi;Liu, Bang;Zhang, Fu-Xing;Wang, Zhi-Qiang;Hu, Qin-Yu;Xu, Zhi-Feng;Li, Jin-Heng. And the article was included in Organic Chemistry Frontiers in 2022.Application In Synthesis of 5-Chloro-2-(phenylethynyl)benzaldehyde The following contents are mentioned in the article:

A DTBP-mediated oxidative [4 + 2]/[3 + 2] annulation was reported between 2-alkynylbenzaldehydes and terminal arylalkenes enabled by aldehyde C(sp2)-H functionalization for assembling a range of benzo[a]fluoren-5-ones, e.g., I, with high step-economy, simple operation under metal-/solvent-free conditions and excellent functional group tolerance. This method was initiated from 2-alkynylbenzaldehyde reaction partners and provides a useful new strategy to construct complex benzo[a]fluoren-5-one scaffolds compared to existing protocols initiating from alkene reaction partners. This study involved multiple reactions and reactants, such as 5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3Application In Synthesis of 5-Chloro-2-(phenylethynyl)benzaldehyde).

5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. Organochlorine compounds are lipophylic, meaning they are more soluble in fat than in water. This gives them a high tenancy to accumulate in the food chain (biomagnification).Application In Synthesis of 5-Chloro-2-(phenylethynyl)benzaldehyde

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Tunable Synthesis of Indeno[1,2-c]furans and 3-Benzoylindenones via FeCl₃-Catalyzed Carbene/Alkyne Metathesis Reaction of o-Alkynylbenzoyl Diazoacetates was written by Li, Bin;Shen, Nana;Yang, Yujie;Zhang, Xinying;Fan, Xuesen. And the article was included in Organic Letters in 2021.Application of 1186603-47-3 The following contents are mentioned in the article:

An efficient synthesis of indeno[1,2-c]furan and 3-benzoylindenone derivatives through a FeCl₃-catalyzed carbene/alkyne metathesis reaction of o-alkynylbenzoyl diazoacetates is presented. Mechanistically, the key intermediate, vinyl iron carbene, is formed by 5-exo-dig carbocyclization and terminated with a formal [3 + 2] cycloaddition or carbonylation. To the best of knowledge, this is the first example in which FeCl₃ is used as a catalyst for a carbene/alkyne metathesis reaction. Finally, derivatization reactions were carried out to showcase the value of the products. This study involved multiple reactions and reactants, such as 5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3Application of 1186603-47-3).

5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst.Application of 1186603-47-3

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Tetrabutylammonium bromide-catalyzed tandem addition-cyclization of o-aralkynylaryl aldehydes with trimethyl(trifluoromethyl)silane. Synthesis of trifluoromethyl group-containing phthalans was written by Hu, Bo-Lun;Li, Chun-Lin;Liao, Zhi-Yong;Zhang, Xing-Guo. And the article was included in Synlett in 2013.HPLC of Formula: 1186603-47-3 The following contents are mentioned in the article:

A Bu₄NBr-catalyzed trifluoromethylation-cyclization reaction of o-aralkynylaryl aldehydes with Me₃SiCF₃ and CsF was developed. A variety of 1-alkylidene-3-(trifluoromethyl)phthalans were prepared in moderate to excellent yields by tandem nucleophilic addition and cyclization. The configuration of the product (1Z)-1-(4-chlorobenzylidene)-3-(trifluoromethyl)-1,3-dihydro-2-benzofuran was unambiguously confirmed by single-crystal X-ray diffraction anal. and its data were deposited at the Cambridge Crystallog. Data Center as supplementary publication number CCDC 968707. This study involved multiple reactions and reactants, such as 5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3HPLC of Formula: 1186603-47-3).

5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. Alkyl chlorides are versatile building blocks in organic chemistry. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available.HPLC of Formula: 1186603-47-3

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics