Category: 1186603-47-3

Direct access to benzo[b]fluorenes via a gold-catalysed A³-coupling strategy was written by Lustosa, Danilo M.;Cieslik, Patrick;Hartmann, Deborah;Bruckhoff, Tim;Rudolph, Matthias;Rominger, Frank;Hashmi, A. Stephen K.. And the article was included in Organic Chemistry Frontiers in 2019.Recommanded Product: 1186603-47-3 The following contents are mentioned in the article:

An one-pot atom- and step-economical method for the synthesis of benzo[b]fluorenes, from aldehydes, alkynes and amines proceeded via an A³-coupling/formal [4 + 2] thermal cyclization was described. The transformation generated water as the only byproduct and three new carbon-carbon bonds were simultaneously formed. The scope was demonstrated by the synthesis of benzo[b]fluorenes and by specific designing of starting materials, regiocontrol could be accessed for some substrates. This study involved multiple reactions and reactants, such as 5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3Recommanded Product: 1186603-47-3).

5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control.Recommanded Product: 1186603-47-3

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Cu(OAc)₂-Catalyzed Aerobic Oxidative Dehydrogenation Coupling: Synthesis of Heptacyclic Quinolizino[3,4,5,6-kla]perimidines was written by Feng, Bin-Bin;Liu, Jian-Quan;Wang, Xiang-Shan. And the article was included in Journal of Organic Chemistry in 2017.Computed Properties of C15H9ClO The following contents are mentioned in the article:

A Cu(OAc)₂-catalyzed domino tricyclization between naphthalene-1,8-diamine and 2-(phenylethynyl)benzaldehyde is described, enabling aerobic oxidative dehydrogenation coupling to access heptacyclic quinolizino[3,4,5,6-kla]perimidines. In this reaction, the formation of three new rings and four new bonds was achieved in a functional-group-compatible fashion, allowing a facile method toward fused aza-heterocycles containing both quinolizine and perimidine moieties. This study involved multiple reactions and reactants, such as 5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3Computed Properties of C15H9ClO).

5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3) belongs to organic chlorides. Organochlorines are organic compounds having multiple chlorine atoms. They were the first synthetic pesticides that were used in agriculture. They are resistant to most microbial and chemical degradations.While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.Computed Properties of C15H9ClO

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Pd(OAc)₂-catalyzed tandem reactions for the synthesis of indol-3-yl substituted 1H-isochromenes and 1,2-dihydroisoquinolines was written by Wang, Huan;Han, Xiuling;Lu, Xiyan. And the article was included in Chinese Journal of Chemistry in 2011.Category: chlorides-buliding-blocks The following contents are mentioned in the article:

A Pd(II)-catalyzed tandem annulation of 2-(alkynyl)benzaldehyde derivatives or benzaldimines with indole derivatives by initial intermol. addition of the indoles to the carbonyl or imine group followed by the nucleopalladation of an intramol. alkyne and quenching of the C-Pd bond by protonolysis to regenerate the Pd(II) species was developed. The synthesis of the target compounds was achieved under mild reaction conditions, without the necessity of a redox system. This study involved multiple reactions and reactants, such as 5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3Category: chlorides-buliding-blocks).

5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. Alkyl chlorides readily react with amines to give substituted amines. Alkyl chlorides are substituted by softer halides such as the iodide in the Finkelstein reaction.Category: chlorides-buliding-blocks

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Efficient generation of biologically active H-pyrazolo[5,1-a]isoquinolines via multicomponent reaction was written by Chen, Zhiyuan;Wu, Jie. And the article was included in Organic Letters in 2010.Computed Properties of C15H9ClO The following contents are mentioned in the article:

A highly efficient multicomponent reaction of 2-alkynylbenzaldehyde, sulfonohydrazide, alc., and α,β-unsaturated aldehyde or ketone is disclosed, which generates the diverse H-pyrazolo[5,1-a]isoquinolines in good yields. This reaction proceeds with good functional group tolerance under mild conditions with high efficiency and excellent selectivity. Preliminary biol. assays show that some of these compounds display promising activities as CDC25B inhibitor, TC-PTP inhibitor, and PTP1B inhibitor. This study involved multiple reactions and reactants, such as 5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3Computed Properties of C15H9ClO).

5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3) belongs to organic chlorides. Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. The hydrocarbon processing industry (HPI) and others are affected by damage caused by these substances. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst.Computed Properties of C15H9ClO

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

CuI-catalyzed domino reactions for the synthesis of benzoxazine-fused isoquinolines under microwave irradiation was written by Zhao, Yun-Hui;Li, Yubo;Guo, Tao;Tang, Zilong;Deng, Keqin;Zhao, Gang. And the article was included in Synthetic Communications in 2016.Related Products of 1186603-47-3 The following contents are mentioned in the article:

A small library of benzoxazine-fused isoquinolines, e.g., I, were synthesized under microwave irradiation via CuI-catalyzed domino reactions of o-alkynyl aldehydes and amines having embedded nucleophiles. This strategy offered a operationally simple, environmentally acceptable route to synthesize the benzoxazine-fused isoquinolines in moderate to good yields. All new compounds were characterized by ¹H NMR, ¹³C NMR, IR, and high-resolution mass spectrometry techniques. This study involved multiple reactions and reactants, such as 5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3Related Products of 1186603-47-3).

5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3) belongs to organic chlorides. Organic chlorides can be used in production of: PVC, pesticides, chloromethane, teflon, insulators.While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.Related Products of 1186603-47-3

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Radical Cascade Bicyclization/Aromatization of 1,7-Enynes with 1,3-Dicarbonyl Compounds towards 2,3-Dihydro-1H-cyclopenta[a]naphthalenes was written by Cai, Tao;Zhang, Zhebing;Li, Peiqin;Sun, Tao;Chen, Xinyu;Ni, Yuqi;Chen, Jianhui;Xu, Huiting;Xu, Yanfei;Wu, Chunlei;Shen, Runpu;Gao, Yuzhen. And the article was included in Advanced Synthesis & Catalysis in 2021.Product Details of 1186603-47-3 The following contents are mentioned in the article:

An Ag-catalyzed radical cascade bicyclization/aromatization of C-linked 1,7-enynes with 1,3-dicarbonyls was achieved, providing a step- and atom-economy approach for the construction of 2,3-dihydro-1H-cyclopenta[a]naphthalenes, an important structural scaffold existed in biol. active compounds From this transformation, structurally diverse 2,3-dihydro-1H-cyclopenta[a]naphthalenes were obtained in moderate to good yields with high regioselectivity. Moreover, the further product derivatizations were also exemplified. This study involved multiple reactions and reactants, such as 5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3Product Details of 1186603-47-3).

5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3) belongs to organic chlorides. Organochlorines are organic compounds having multiple chlorine atoms. They were the first synthetic pesticides that were used in agriculture. They are resistant to most microbial and chemical degradations. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control.Product Details of 1186603-47-3

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Gold(I)-Catalyzed 1,4-and/or 1,5-Heteroaryl Migration Reactions through Regiocontrolled Cyclizations was written by Wang, Chengyu;Xie, Xin;Liu, Jun;Liu, Yuanhong;Li, Yuxue. And the article was included in Chemistry – A European Journal in 2015.Name: 5-Chloro-2-(phenylethynyl)benzaldehyde The following contents are mentioned in the article:

Gold(I)-catalyzed regioselective cycloisomerizations of furan-ynes were described. The reaction provided a concise access to stereodefined trisubstituted alkenes by endo cyclization with concomitant 1,5-migration of the furanyl group in the presence of unactivated 3° mol. sieves. In the absence of mol. sieves, indene products were generated by exo cyclization, followed by 1,4-furanyl migration/cyclization. The scope for 1,5-migrations was extended to other heterocycles, such as benzofurans, thiophenes and pyrroles. This study involved multiple reactions and reactants, such as 5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3Name: 5-Chloro-2-(phenylethynyl)benzaldehyde).

5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3) belongs to organic chlorides. Organochlorines stimulate the central nervous system and cause convulsions, tremor, nausea, and mental confusion. Examples are dichlorodiphenyltrichloroethane (DDT), chlordane, lindane, endosulfan, and dieldrin. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.Name: 5-Chloro-2-(phenylethynyl)benzaldehyde

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Platinum-Catalyzed Tandem Cycloisomerization Reaction of Benzoendiynyl Esters: Regioselective Long-Range 1,5-Acyl Migration was written by Chen, Zhiyuan;Jia, Xuegong;Huang, Jiapian;Yuan, Jianjun. And the article was included in Journal of Organic Chemistry in 2014.Product Details of 1186603-47-3 The following contents are mentioned in the article:

A Pt^II-catalyzed intramol. chemo- and regioselective pentannulation/long-range 1,5-acyl migration reaction is described. This cascade cycloisomerization protocol produces a wide variety of benzofulvene diketones in good to excellent yields with exclusively the Z configuration of the exocyclic double bond of the final product. The ¹⁸O isotope experiment together with ¹³C NMR, HRMS, and HMBC analyses confirmed an interesting long-range acyl rearrangement process in this transformation. This study involved multiple reactions and reactants, such as 5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3Product Details of 1186603-47-3).

5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3) belongs to organic chlorides. Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. The hydrocarbon processing industry (HPI) and others are affected by damage caused by these substances. Alkyl chlorides readily react with amines to give substituted amines. Alkyl chlorides are substituted by softer halides such as the iodide in the Finkelstein reaction.Product Details of 1186603-47-3

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Dynamic Kinetic Resolution in Gold-Catalyzed (4 + 2)-Annulations between Alkynyl Benzaldehydes and Allenamides to Yield Enantioenriched All-Carbon Diarylalkylmethane Derivatives was written by Pandit, Yashwant Bhaskar;Liu, Rai-Shung. And the article was included in Organic Letters in 2022.Computed Properties of C15H9ClO The following contents are mentioned in the article:

This work reports the synthesis of diarylmethane derivatives via gold-catalyzed (4 + 2)-annulations between alkynyl benzaldehydes and allenamides, followed by an aza-Claisen rearrangement. Deuterium labeling and crossover experiments have been performed to confirm this proposed mechanism. With racemic 3-substituted allenamides in a substrate ratio (1:1), authors employ chiral gold catalysts to achieve a dynamic kinetic resolution to obtain enantioenriched diarylalkylmethane derivatives with high e.r. levels (up to 93:7). This study involved multiple reactions and reactants, such as 5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3Computed Properties of C15H9ClO).

5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst.Computed Properties of C15H9ClO

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Enantioselective Synthesis of Isoquinolines: Merging Chiral-Phosphine and Gold Catalysis was written by Gao, Yu-Ning;Shi, Feng-Chen;Xu, Qin;Shi, Min. And the article was included in Chemistry – A European Journal in 2016.Formula: C15H9ClO The following contents are mentioned in the article:

The highly enantioselective synthesis of dihydroisoquinoline derivatives from aromatic sulfonated imines tethered with an alkyne moiety, through a one-pot asym. relay catalysis of chiral-phosphine and gold catalysts, is reported. Enantiomerically enriched dihydroisoquinoline derivatives were afforded in good yields and good-to-excellent ee values under mild conditions, based on the asym. aza-Morita-Baylis-Hillman reaction. Dihydroisoquinoline derivatives containing two chiral centers were also synthesized through further transformations. This study involved multiple reactions and reactants, such as 5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3Formula: C15H9ClO).

5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3) belongs to organic chlorides. Organic chlorides can be used in production of: PVC, pesticides, chloromethane, teflon, insulators. Organochlorine compounds are lipophylic, meaning they are more soluble in fat than in water. This gives them a high tenancy to accumulate in the food chain (biomagnification).Formula: C15H9ClO

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics