Category: 118-45-6

Huang, Lingyu; Xie, Rongrong; Wen, Chaoying; Yang, Yanyan; Wang, Yiwen; Ren, Shiyan; Huang, Bin; Li, Shiqing published the artcile< Decarbonylative/decarboxylative [4 + 2] annulation of phthalic anhydrides and cyclic iodoniums towards triphenylenes>, Related Products of 118-45-6, the main research area is phthalic anhydride diaryliodonium salt palladium catalyst decarbonylative decarboxylative cyclization; triphenylene preparation.

A palladium-catalyzed decarbonylative/decarboxylative [4 + 2] annulation of phthalic anhydrides with cyclic diaryliodonium salts to synthesize triphenylenes was developed. The reaction showed broad substrate scope with a high yield of up to 99%, and it provided an efficient and fast way to access functionalized triphenylenes in only one hour.

Organic & Biomolecular Chemistry published new progress about Cyclization ([4+2], decarbonylative, decarboxylative). 118-45-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C8H3ClO3, Related Products of 118-45-6.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Wei, Haibing; Fang, Xingzhong; Han, Ying; Hu, Benlin; Yan, Qing published the artcile< Synthesis and characterization of poly(thioether ether sulfone imide)s derived from isomeric bis(chlorophthalimide)s and bis(4-mercaptophenyl) sulfone>, Category: chlorides-buliding-blocks, the main research area is polyether polyimide polysulfone polythioether synthesis thermal mech property.

A series of isomeric bis(chlorophthalimide)s (BCPIs) were conveniently prepared from 3-chlorophthalic anhydride, 4-chlorophthalic anhydride, and mixtures thereof. Polymerization of BCPIs with bis(4-mercaptophenyl) sulfone (BMPS) proceeded smoothly in the presence of tributylamine, from which a class of isomeric poly(thioether ether sulfone imide)s (PTESIs) with inherent viscosities of 0.45-0.82 dL/g were obtained. The solubility, thermal stability, and mech. properties of these polymers were characterized. Compared to the PTESIs derived from single BCPIs, i.e., 3,3′-, 3,4′-, or 4,4′-BCPIs, the PTESIs derived from mixed BCPIs showed better solubility and higher storage modulus. These PTESIs also demonstrated good thermal stability, giving only 5% weight loss at temperature of 490° in nitrogen atm. The glass transition temperatures (T gs) of these isomeric PTESIs were between 242 and 265°, and were increased with increasing of the ratio of 3-chlorophthalimide unit in the polymer backbone.

European Polymer Journal published new progress about Complex modulus, tan δ. 118-45-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C8H3ClO3, Category: chlorides-buliding-blocks.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Barn, David R.; Morphy, J. Richard published the artcile< Solid-Phase Synthesis of Cyclic Imides>, SDS of cas: 118-45-6, the main research area is imide cyclic combinatorial library solid phase synthesis; phthalimidoethylisoquinoline analog combinatorial library solid phase synthesis; isoquinoline phthalimidoethyl analog preparation.

A cyclative cleavage strategy for the synthesis of cyclic imides on a polystyrene resin is described. After optimization of the cleavage conditions, a small array of succinimides and phthalimides was synthesized. The methodol. was then applied to a drug discovery project, in which it was used to synthesize a new class of δ-opioid receptor ligands, analogs of the isoquinoline I, by both automated and manual methods.

Journal of Combinatorial Chemistry published new progress about Combinatorial library. 118-45-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C8H3ClO3, SDS of cas: 118-45-6.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Han, Ying; Fang, Xing Zhong; Zuo, Xiu Xia published the artcile< The influence of molecular weight on properties of melt-processable copolyimides derived from thioetherdiphthalic anhydride isomers>, Electric Literature of 118-45-6, the main research area is thiobisisobenzofurandione oxydianiline polyimide strength melt processing.

A series of novel melt-processable copolyimides based on mixed thioetherdiphthalic anhydride (TDPA) isomers and 4,4′-oxydianiline (4,4′-ODA) were synthesized by a one-step polycondensation. Mol. weight of copolyimides was controlled with stoichiometric offsets in favor of 4,4′-ODA. All of the resulting polyimides (PIs) were amorphous and have nice solubility With increase in mol. weight, the glass transition temperatures of copolyimides increased from 248 to ca. 270 °C based on DSC measurements. These copolyimides displayed excellent thermal and thermooxidative stability, as evidenced by thermogravimetric anal. in both air and nitrogen atmospheres. The melt processability, thermoplastic response, melt stability, and their dependence on mol. weight of the copolyimides were investigated in terms of rheol. measurements by monitoring the melt viscosity after residence at various times and temperatures

Journal of Materials Science published new progress about Complex modulus, tan δ. 118-45-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C8H3ClO3, Electric Literature of 118-45-6.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Michael, William R.; King, William R.; Wakim, J. M. published the artcile< Metabolism of disodium ethane-1-hydroxy-1,1-diphosphonate (disodium etidronate) in the rat, rabbit, dog, and monkey>, Reference of 118-45-6, the main research area is etidronate disodium metabolism; absorption etidronate disodium.

After administration by intragastric cannula, the absorption of disodium etidronate [7414-83-7] (10-20 mg/kg) from the gastrointestinal tract of adult rats, weanling rats, rabbits, monkeys, adult dogs, and young dogs was 3, 10.5, 3.8, 6, 14, and 21% resp. Absorption was primarily from the stomach. I was not metabolized by the rat or dog, and there was virtually no enterohepatic circulation of I in the rat. Approx. half of the absorbed I was excreted in the urine, while the remaining half was deposited in the skeleton. The half-life of I the skeleton of the rat was 12 days.

Toxicology and Applied Pharmacology published new progress about Bone. 118-45-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C8H3ClO3, Reference of 118-45-6.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Gao, Wei; Li, Xiaotian; Ren, Da; Sun, Susu; Huo, Jingqian; Wang, Yanen; Chen, Lai; Zhang, Jinlin published the artcile< Design and synthesis of N-phenyl phthalimides as potent protoporphyrinogen oxidase inhibitors>, Quality Control of 118-45-6, the main research area is phenyl phthalimide preparation protoporphyrinogen oxidase inhibitor herbicidal activity docking; N-phenyl phthalimides; herbicidal activity; molecular design; protoporphyrinogen oxidase.

A series of novel phthalimide derivatives I [R1 = H, F, Cl; R2 = H, Me, Cl, NO2; Ar = 5-methylisoxazol-3-yl, thiophen-2-ylmethyl, 4-bromo-2,6-difluorophenyl, etc.] were designed by mol. docking studies targeting the crystal structure of mitochondrial PPO from tobacco (mtPPO, PDB: 1SEZ) by using Flumioxazin as a lead, after which the derivatives were synthesized and characterized, and their herbicidal activities were subsequently evaluated. The herbicidal bioassay results showed that compounds such as I [R1 = R2 = H; Ar = 4-bromo-2,6-difluorophenyl], [R1 = Cl; R2 = H; Ar = 5-methylisoxazol-3-yl, thiophen-2-ylmethyl, 4-fluoro-3-methoxycarbonyl-phenyl] and [R1 = F; R2 = H; Ar = 4-bromo-2,6-difluorophenyl] had good herbicidal activities; among them I [R1 = R2 = H; Ar = 4-bromo-2,6-difluorophenyl], showed excellent herbicidal efficacy against A. retroflexus and B. campestris via the small cup method and via pre-emergence and post-emergence spray treatments. The efficacy was comparable to that of the com. herbicides Flumioxazin, Atrazine, and Chlortoluron. Further, the enzyme activity assay results suggest that the mode of action of compound I [R1 = R2 = H; Ar = 4-bromo-2,6-difluorophenyl] involved the inhibition of the PPO enzyme, and showed better inhibitory activity against PPO than did Flumioxazin. These results indicate that our mol. design strategy contributes to the development of novel promising PPO inhibitors.

Molecules published new progress about Aromatic amines Role: RCT (Reactant), RACT (Reactant or Reagent). 118-45-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C8H3ClO3, Quality Control of 118-45-6.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Yan, Jingling; Li, Taihang; Wang, Zhen; Gao, Lianxun; Ding, Mengxian published the artcile< Hydrazine-based polyimides from isomeric bis(chlorophthalimide)s>, Related Products of 118-45-6, the main research area is hydrazine isomeric dichloro bisphthalimide thiobisbenzenethiol polyimide thermal mech property.

3,3′-Dichloro-N,N’-bisphthalimide (3,3′-DCBPI), 3,4′-dichloro-N,N’-bisphthalimide (3,4′-DCBPI), and 4,4′-dichloro-N,N’-bisphthalimide (4,4′-DCBPI) were synthesized from 3- or 4-chlorophthalic anhydrides and hydrazine in glacial acetic acid. The yield of 3,3′-DCBPI (90%) was much higher than that of 4,4′-DCBPI (33%) because of the better stability of the intermediate, 3-chloro-N-aminophthalimide, and 3,3′-DCBPI. A series of hydrazine-based polyimides were prepared from isomeric DCBPIs and 4,4′-thiobisbenzenethiol (TBBT) in N,N-dimethylacetamide in the presence of tributylamine. Inherent viscosity of these polymers was in the range of 0.51-0.69 dL/g in 1-methyl-2-pyrrolidinone (NMP) at 30 °C. These polyimides were soluble in 1,1,2,2-terachloroethane, NMP, and phenols. The 5% weight-loss temperatures (T5%s) of the polymers were near 450 °C in N2. Their glass-transition temperatures (Tgs) determined by dynamic mech. thermal anal. and differential scanning calorimetry increased according to the order of polyimides based on 4,4′-DCBPI, 3,4′-DCBPI, and 3,3′-DCBPI. The hydrolytic stability of these polymers was measured under acid, basic, and neutral conditions and the results indicated that the order was 3,3′-DCBPI/TBBT > 3,4′-DCBPI/TBBT > 4,4′-DCBPI/TBBT.

Journal of Polymer Science, Part A: Polymer Chemistry published new progress about Elongation at break. 118-45-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C8H3ClO3, Related Products of 118-45-6.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Kawamata, Yu; Hayashi, Kyohei; Carlson, Ethan; Shaji, Shobin; Waldmann, Dirk; Simmons, Bryan J.; Edwards, Jacob T.; Zapf, Christoph W.; Saito, Masato; Baran, Phil S. published the artcile< Chemoselective Electrosynthesis Using Rapid Alternating Polarity>, Related Products of 118-45-6, the main research area is electrochem chemoselective reduction ketone rapid alternating polarity.

Challenges in the selective manipulation of functional groups (chemoselectivity) in organic synthesis have historically been overcome either by using reagents/catalysts that tunably interact with a substrate or through modification to shield undesired sites of reactivity (protecting groups). Although electrochem. offers precise redox control to achieve unique chemoselectivity, this approach often becomes challenging in the presence of multiple redox-active functionalities. Historically, electrosynthesis has been performed almost solely by using d.c. (DC). In contrast, applying a.c. (AC) has been known to change reaction outcomes considerably on an anal. scale but has rarely been strategically exploited for use in complex preparative organic synthesis. Here we show how a square waveform employed to deliver elec. current-rapid alternating polarity (rAP)-enables control over reaction outcomes in the chemoselective reduction of carbonyl compounds, one of the most widely used reaction manifolds. The reactivity observed cannot be recapitulated using DC electrolysis or chem. reagents. The synthetic value brought by this new method for controlling chemoselectivity is vividly demonstrated in the context of classical reactivity problems such as chiral auxiliary removal and cutting-edge medicinal chem. topics such as the synthesis of PROTACs.

Journal of the American Chemical Society published new progress about Carbonyl group. 118-45-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C8H3ClO3, Related Products of 118-45-6.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Saito, Yuta; Higashihara, Tomoya; Ueda, Mitsuru published the artcile< Highly refractive and photosensitive polyimide>, Application of C8H3ClO3, the main research area is refractive photosensitive polyimide.

A highly refractive sulfur-containing photosensitive polyimide (PSPI) based on the PI from 4,4′-[p-thiobis(phenylenesulfanyl)]diphthalic anhydride (3SDEA) and 4,4′-thiodianiline (SDA), 4,4′-methylenebis[2,6-bis(methoxymethyl)phenol] (MBMP) as a crosslinker, and (5-propylsulfonyloxyimino-5H-thiophen-2-ylidene)-(2-methylphenyl)acetonitrile (PTMA) as a photoacid generator has been developed. The matrix polymer showed high transparency in the g-line region and the high reflective index of 1.7452 and low birefringence of 0.0081. The PSPI consisting of the PI (84.8 wt%), MBHP (11.0 wt%), and PTMA (4.2 wt%) exhibited the high sensitivity (D0.5) of 36 mJ/cm2 and good contrast (γ0.5) of 5.1, resp., producing a clear neg.-tone line-and-space pattern with 8-μm resolution

Journal of Photopolymer Science and Technology published new progress about Dissolution. 118-45-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C8H3ClO3, Application of C8H3ClO3.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Xu, Dan; Yao, Zhengjun; Zhou, Jintang published the artcile< Mechanical and thermal properties of a novel bismaleimide matrix resin for high-performance composite materials>, Name: 5-Chloroisobenzofuran-1,3-dione, the main research area is amino polythioetherimide bismaleimidodiphenyl methane diallylbisphenol resin mech thermal property.

A novel bismaleimide matrix resin of amino-polythioetherimide (PTEI-N)/4,4′-bismaleimidodiphenyl methane (BDM)/2,2′-diallylbisphenol A (BA) was prepared Mech. measurements, dynamic thermomech. anal., thermogravimetric anal. (TGA), and microanalyses were conducted to assess the mech. properties, thermal resistance, and morphol. of the modified resin. Results demonstrate that the addition of PTEI-N has significant effects on the mech. properties of the BDM/BA system. Compared with the pure BDM/BA resin, the PTEI-N/BDM/BA system markedly improves the tensile strength, flexural strength, and impact strength, given an appropriate amount of PTEI-N. Scanning electron microscopic and energy-dispersive spectroscopic results show that PTEI-N is distributed uniformly in the BDM/BA system, and the interfacial compatibility between the PTEI-N and BDM/BA phase is excellent. TGA shows that the BDM/BA resin continues to exhibit good thermal resistance with a suitable dosage of PTEI-N. These changes in properties are closely correlated with the addition of PTEI-N. The PTEI-N/BDM/BA resin system shows potential applications in many fields.

High Performance Polymers published new progress about Bending strength. 118-45-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C8H3ClO3, Name: 5-Chloroisobenzofuran-1,3-dione.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics