Author: Jessica.F

Chibowski, Emil J. published the artcileSurface free energy and wettability of silyl layers on silicon determined from contact angle hysteresis, COA of Formula: C9H20Cl2Si, the publication is Advances in Colloid and Interface Science (2005), 113(2-3), 121-131, database is CAplus and MEDLINE.

Using the literature data [A.Y. Fadeev and T.J. McCarthy, Langmuir 15(1999) 3759; A.Y. Fadeev and T.J. McCarthy, Langmuir 16(2000) 7268] of the advancing and receding contact angles for H₂O, diiodomethane and hexadecane measured on various hydrophobic silyl layers (mostly monolayers) produced on Si wafers the apparent surface free energies γ^tot_s were calculated by applying new model of the contact angle hysteresis interpretation. For the same silyl layer, the calculated γ^tot_s values to some degree depended on the probe liquid used. Therefore, thus calculated the surface free energies should be considered as apparent ones. Also, also the values of the dispersion component γ_s^d of these layers depend on the probe liquid used, but to a less degree. This must be due to the strength of the force field originating from the probe liquid and the spacing between the interacting mols. The relations between γ^tot_s and γ^d_s are discussed from the equations derived. It may be postulated that applying proposed model of the contact angle hysteresis and calculating the apparent total surface free energies and the dispersion contributions better insight into wetting properties of the silyled Si surface can be achieved.

Advances in Colloid and Interface Science published new progress about 14799-93-0. 14799-93-0 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is Dichloro(methyl)(octyl)silane, and the molecular formula is C9H20Cl2Si, COA of Formula: C9H20Cl2Si.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Chambers, Henry F. published the artcileRifabutin to the rescue?, Product Details of C12H15ClO3, the publication is Journal of Infectious Diseases (2020), 222(9), 1422-1424, database is CAplus and MEDLINE.

A review. Rifampin as the most interesting new antibiotic, specifically noting its in vitro activity against methicillin-resistant staphylococci and its good oral bioavailability. Administration of rifampin in combination with another active agent was found to prevent emergence of resistance. The activity of rifampin against bacteria within biofilms is a strong rationale for current recommendations for its use in combination therapy to treat device-related staphylococcal infections, eg, prosthetic joint infections, spinal implant infections, prosthetic-valve endocarditis, cerebrospinal fluid shunt infections. A partial list includes anticonvulsants, antiarrhythmics, antiestrogens, antipsychotics, oral anti- coagulants, antifungals, antibacterials, antiretrovirals, barbiturates, β-blockers, benzodiazepines and related drugs, calcium channel blockers, corticosteroids, cardiac glycosides preparations, clofibrate, oral contraceptives, estrogens, oral hypo- glycemic agents, immunosuppressive agents, levothyroxine, losartan, narcotic analgesics, methadone, progestins, selective 5-HT3 receptor antagonists, statins, theophylline, thiazolidinediones, and tri- cyclic antidepressants. Rifamycins (eg, rifampin, rifabutin, rifapentine, and refalazil) all have the same mechanism of action. A randomized controlled trial is warranted to define the efficacy and advantages of rifabutin compared with rifampin in combination therapy for device-related infections, so that clinicians will not have to rely on personal experience, anecdotal reports, and data from observational studies, as was the case for decades with rifampin.

Journal of Infectious Diseases published new progress about 637-07-0. 637-07-0 belongs to chlorides-buliding-blocks, auxiliary class Inhibitor,Cell Cycle,PPAR, name is Ethyl 2-(4-chlorophenoxy)-2-methylpropanoate, and the molecular formula is C12H15ClO3, Product Details of C12H15ClO3.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Cadogan, J. I. G. published the artcileThe production of 1,4-dialkylpiperazines by the thermal decomposition of 1,1,4,4-tetraalkylpiperazinium salts, COA of Formula: C5H13Cl2N, the publication is Journal of the Chemical Society (1955), 2971-3, database is CAplus.

Several 1,1,4,-4-tetraalkylpiperazinium dihalides were prepared and their pyrolysis products studied. All the dichlorides investigated gave the 1,4-dialkylpiperazine and alkyl chloride in 72-88% yield at atm. pressure. The dibromides under comparable conditions gave lower yields. Et₂NCH₂CH₂Cl.HCl (0.5 mole) added to a vigorously stirred ice-cold mixture of 500 ml. H₂O and 250 ml. Et₂O, treated with solid Na₂CO₃, and the layers separated yielded from the dried (MgSO₄) Et₂O layer a yellow oil which, refluxed with 250 ml. EtOH 3 hrs., gave 80% 1,1,4,4-tetraethylpiperazinium dichloride (I), plates, m. above 300° (from MeOH/acetone). Similarly, MeEtNCH₂CH₂Br.HBr gave 65% 1,4-diethyl-1,4-dimethylpiperazinium dibromide, m. 295° (from aqueous EtOH), and (CH₂Br)₂ with (CH₂NMe₂)₂ in EtOH gave 83% 1,1,4,4-tetramethylpiperazinium dibromide (II), m. above 330° (from aqueous EtOH). Ethylene oxide (40 g.) passed into 101 g. NHPr₂, 20 ml. N H Cl added, and the mixture, which became dark, kept 2 hrs. at 60°, yielded from the organic layer 75% Pr₂NCH₂CH₂OH, b₂₀ 90-2° n_D²⁵ 1.4375, converted into Pr₂NCH₂CH₂Cl.HCl with excess SOCl₂ in dry C₆H₆ at 0°. The free base was isolated and converted as above to 51% 1,1,4,4-tetrapropylpiperazinium dichloride (III), m. 295° (from EtOH/EtOAc). Similarly, ethylene oxide and NHBu₂ gave 68% Bu₂NCH₂CH₂OH, b₁₀ 104°, n_D²⁵ 1.4422, converted to 47% 1,1,4,4-tetrabutylpiperazinium dichloride monohydrate (IV), m. 239° (from aqueous EtOH-EtOAc). Me₂NCH₂CH(OH)Me was converted into Me₂NCH₂CHMeCl.HCl by the method of C.A. 42, 4934i and the latter converted to 65% hexamethylpiperazinium dichloride (V), m. 275° (from EtOH-C₆H₆). The tetraalkylpiperazinium salts were warmed with a free flame until decomposition began, with slight suction maintained to draw the alkyl halides into a cold trap, and the bases collected and fractionated from KOH. In this way were prepared the following 1,4-dialkylpiperazines (alkyl, % yield, b.p./mm., n_D²⁵ and m.p. of: dimethiodide given): Et, 88, 68°/10, 1.4520, 240°; Pr, 80, 84°/10, 1.4514 228°; Bu, 72, 112°/10, 1.4542, 215°; Me, 10., 130°/760, 1.4448, 310°. V gave 87% tetramethylpiperazine, b₁₀ 62, n_D²⁵ 1.4522; monomethiodide, m. 251°.

Journal of the Chemical Society published new progress about 4584-49-0. 4584-49-0 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Salt,Amine,Aliphatic hydrocarbon chain, name is 2-Chloro-N,N-dimethylpropan-1-amine hydrochloride, and the molecular formula is C5H13Cl2N, COA of Formula: C5H13Cl2N.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Burger, L. L. published the artcileUranium and plutonium extraction by organophosphorus compounds, Safety of Diethyltrichloromethylphosphonate, the publication is Journal of Physical Chemistry (1958), 590-3, database is CAplus.

Organic phosphates, phosphonates, phosphinates, and phosphine oxides were compared as solvents for U and Pu nitrates. Distribution coefficients for U(VI), Pu(IV), and Pu(VI) indicated a large difference in solvent strength among these groups of compounds The introduction of an electroneg. group greatly reduced the solvent strength. The P-O stretching frequency was correlated with solvent strength for these compounds Some solid complexes of the organophosphorus compounds with UO₂(NO₃)₂ were isolated.

Journal of Physical Chemistry published new progress about 866-23-9. 866-23-9 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is Diethyltrichloromethylphosphonate, and the molecular formula is C5H10Cl3O3P, Safety of Diethyltrichloromethylphosphonate.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Brenner, Sydney published the artcileSupravital staining of mitochondria with phenosafranine dyes, Application of 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride, the publication is Biochimica et Biophysica Acta (1953), 480-6, database is CAplus and MEDLINE.

The more basic a phenosafranine (I) dye, the lower is the concentration of dye necessary for the supravital staining of mitochondria, as determined by studies on the supravital staining of human lymphocyte mitochondria with various sym. and unsym. I dyes. The dyes studied were in the order of increasing basicity of the terminal atoms (as determined by spectral measurements) and staining ability, I, dimethyl-I, diethyl-I, tetramethyl-I, diethyldimethyl-I, tetraethyl-I, and Janus green B. The results are discussed in relation to theories of supravital staining.

Biochimica et Biophysica Acta published new progress about 4569-86-2. 4569-86-2 belongs to chlorides-buliding-blocks, auxiliary class Other Aromatic Heterocyclic,Salt,Amine,Benzene, name is 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride, and the molecular formula is C22H23ClN4, Application of 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Bennett, George Macdonald published the artcileβ,β’-Dichlorodiethyl disulfide, Related Products of chlorides-buliding-blocks, the publication is Journal of the Chemical Society, Transactions (1921), 418-25, database is CAplus.

The behavior of S₂Cl₂ and C₂H₄ has been the subject of some controversy, the issue being whether a monosulfide or a disulfide is formed. Bennett has reinvestigated the reaction at 30-35° and concludes that the liquids are two-phase systems in which the continuous phase is nearly pure S(C₂H₄Cl)₂ and the disperse phase a liquid consisting chiefly of S. The varying behavior on dilution with Et₂O, etc., may be due to different degrees of dispersion. 50 cc. S₂Cl₂ gave 111 g. of a pale amber-colored liquid, d₁₅ 1.373, m. 5-6°; the relative viscosity at 15° was 10.25. which is characteristic of liquid-liquid 2-phase systems. The product b₂₀ 110-20°. The addition of 20 cc. dry Et₂O to 30 cc. of the liquid before distillation produced no separation into 2 phases. 100 cc. Et₂O caused the separation of 4.7 g. of a S-yellow oil, which was impure S. Heating in a stream of dry air for an hr. also caused the separation of S. In each case the m. p. of the sulfide was unaffected. Attempts to prepare the emulsion from the sulfide and S were unsuccessful. SHCH₂CH₂OH (Ann. 124, 257) was prepared by melting 225 g. crystalline Na₂S on the H₂O bath, saturating with H₂S, cooling to 50° and stirring in 70 g. ClCH₂CH₂OH. It b₁₈ 58°, d₄²⁰ 1.1153, n_D²⁰ 1.4443. This was oxidized to β,β’-dichlorodiethyl disulfide C₄H₈Cl₂S₂, by H₂O₂, FeCl₃ or NaBrO, straw-colored oil, b₃₀ 155°, d₄²⁰ 1.3375, (η/η_H2O)₂₀, 6.08. It resembles the monosulfide in many of its properties. Its vesicant action was 1/3 that of the monosulfide. Boiled with PhONa, it yields β,β’-diphenoxydiethyl disulfide, small, silvery plates, m. 96-7°. Na₂S gives S(C₂H₄)₂S. On oxidation it yields C₂H₄O₃ClSNa.H₂O (Ann. 223, 213).

Journal of the Chemical Society, Transactions published new progress about 1002-41-1. 1002-41-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is 1,2-Bis(2-chloroethyl)disulfane, and the molecular formula is C4H8Cl2S2, Related Products of chlorides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Akusoba, E. U. published the artcile6-Coumarinsulfonyl chloride (6CSCL): a fluorescent label for protein molecules, SDS of cas: 10543-42-7, the publication is Fresenius’ Zeitschrift fuer Analytische Chemie (1985), 320(2), 182-3, database is CAplus.

Albumin and γ-globulin were labeled with 6CSCL, purified by gel chromatog. on Sephadex G 25, and the fluorescence and other properties of the labeled proteins were studied. The fluorescence intensity of labeled albumin decreased slightly with increasing temperature and increased sharply with increasing pH. An increase in dielec. constants of solvents was accompanied by a bathochromic shift in fluorescence maximum for labeled γ-globulin. Freeze-dried conjugate lost no fluorescence intensity after refrigeration for 2 wk. 6CSCL resembles dansyl chloride in its reactions and is a promising cheap and stable label for proteins and amino acids.

Fresenius’ Zeitschrift fuer Analytische Chemie published new progress about 10543-42-7. 10543-42-7 belongs to chlorides-buliding-blocks, auxiliary class Other Aromatic Heterocyclic,Chloride,Sulfonyl chlorides,Ester, name is Coumarin-6-sulfonyl chloride, and the molecular formula is C9H5ClO4S, SDS of cas: 10543-42-7.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Abdulla, Riaz F. published the artcileMorpholines. V. Synthesis and properties of some 2-substituted 3-oxo-4H-1,4-oxazines, Computed Properties of 18791-02-1, the publication is Zeitschrift fuer Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, Biochemie, Biophysik, Biologie (1972), 27(12), 1465-70, database is CAplus.

Cyclodehydrochlorination of p-RC6H4N(COCHCl2)CH2COC6H4N-O2-p with Me3COK in Me2SO gave the title compounds (I; R = H or EtO2C; X = OH), which reacted with SOCl2 to give I (X = Cl) (II). Solvolysis with MeOH or amination of II with R21NH gave I (X = MeO or NR21, NR21 = ethyleneimino, 1-pyrrolidinyl, or piperidino).

Zeitschrift fuer Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, Biochemie, Biophysik, Biologie published new progress about 18791-02-1. 18791-02-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is 2,3-Dibromopropionylchloride, and the molecular formula is C3H3Br2ClO, Computed Properties of 18791-02-1.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Abdel-Bary, Hamed M. published the artcileReactions with coumarin: synthesis and reactions of coumarinsulfonamides, COA of Formula: C9H5ClO4S, the publication is Mansoura Science Bulletin, A: Chemistry (1997), 24(1), 161-170, database is CAplus.

Coumarin-6-sulfonyl chloride was amidated with different secondary amines to give coumarin-6-sulfonamides. The latter with hydrazine under controlled conditions effected ring-opening of the lactone ring to afford the corresponding o-hydroxycinnamoyl hydrazides. Hydrazones were obtained by condensation of the latter with aldehydes. Some reactions of the hydrazones or hydrazides were examined

Mansoura Science Bulletin, A: Chemistry published new progress about 10543-42-7. 10543-42-7 belongs to chlorides-buliding-blocks, auxiliary class Other Aromatic Heterocyclic,Chloride,Sulfonyl chlorides,Ester, name is Coumarin-6-sulfonyl chloride, and the molecular formula is C9H5ClO4S, COA of Formula: C9H5ClO4S.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Abdel-Bary, Hamed M. published the artcileReactions with coumarin: synthesis and reactions of coumarin sulfonamides, Safety of Coumarin-6-sulfonyl chloride, the publication is Afinidad (1998), 55(473), 67-71, database is CAplus.

Coumarin-6-sulfonyl chloride was animated with different secondary amines to give the sulfonamides. Treatment of these with hydrazine under controlled conditions effected ring-opening of the lactone ring to afford the corresponding o-hydroxycinnamoyl hydrazides which were converted to hydrazones by reaction with various aldehydes. The hydrazones were cyclized using acetic anhydride to yield oxadiazolines. Reaction of the hydrazides with 4-toluoyl chloride afforded the corresponding N-toluoyl derivatives which cyclized with POCl₃ to the corresponding 1,3,4-oxadiazole derivatives Thiosemicarbazide derivatives were obtained by treatment of the hydrazides with PhNCS. Cyclization of the thiosemicarbazides using POCl₃ afforded the corresponding 1,3,4-thiadiazoles.

Afinidad published new progress about 10543-42-7. 10543-42-7 belongs to chlorides-buliding-blocks, auxiliary class Other Aromatic Heterocyclic,Chloride,Sulfonyl chlorides,Ester, name is Coumarin-6-sulfonyl chloride, and the molecular formula is C9H5ClO4S, Safety of Coumarin-6-sulfonyl chloride.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics