Organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. 6334-18-5, formula is C7H4Cl2O, Name is 2,3-Dichlorobenzaldehyde. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. Formula: C7H4Cl2O.
Fouda, Ahmed M.;Irfan, Ahmad;Al-Sehemi, Abdullah G.;El-Agrody, Ahmed M. research published 《 Synthesis, characterization, anti-proliferative activity and DFT study of 1H-benzo[f]chromene-2-carbothioamide derivatives》, the research content is summarized as follows. Reaction of 7-methoxy-2-naphthol with appropriate aromatic aldehydes and 2-cyano-ethanethioamide provided the corresponding 3-amino-1-aryl-9-methoxy-1H-benzo[f]chromene-2-carbothioamide. The structures of these compounds were established on the basis of IR, 1H NMR, 13C NMR, MS data and elemental anal. Furthermore, the anti-proliferative properties were evaluated against the human cancer cell lines MCF-7, HepG-2 and PC-3 in comparison to the pos. controls Vinblastine and Doxorubicin, employing the viability assay. The obtained results confirmed that some of the tested mols. revealed strong and selective cytotoxic activities against the three cancer cell lines. Moreover, various mol. descriptors, frontier MOs (FMO), Mulliken anal. and electronic properties were studied to probe the biol. activity behavior of the synthesized 1H-benzo[f]chromene-2-carbothioamide derivatives The effect of electron withdrawing groups (EWGs) and electron donating groups (EDGs) were also explored on the structural parameters and electronic nature of compounds The energy gaps, reactivity descriptors values and mol. docking studies exhibited that some 1H-benzo[f]chromene-2-carbothioamide derivatives were active biol. compounds
Formula: C7H4Cl2O, 2,3-Dichlorobenzaldehyde(2,3-DBA)is a useful research compound. Its molecular formula is C7H4Cl2O and its molecular weight is 175.01 g/mol. The purity is usually 95%.
2,3-DBA is an organic compound that is used as a synthetic intermediate in the preparation of other chemicals. It is prepared by reacting 2-chloroacetophenone with hydrochloric acid and sodium carbonate in a reaction vessel. The product can be purified through fractional distillation or crystallization. The optical properties of 2,3-DBA are determined by its dipole moment and the substituents attached to the methylene group. Molecular modeling studies have shown that felodipine can bind to 2,3-DBA through its active methylene group. The reaction products between sulfadiazine and 2,3-DBA are pyridinedicarboxylic acid and 3-chlorobenzaldehyde.
2,3-DBA is part of a group of Benzaldehyde (B119740) derivatives that exhibit activity against Mycobacterium tuberculosis, the bacteria responsible for causing tuberculosis in humans. 2,3-DBA is also used as a reagent to synthesize (E)-2-(2-arylhydrazinyl)quinoxalines, compounds that have potent anticancer activity., 6334-18-5.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics