The class of organic compounds having covalently a bonded chlorine atom is called organic chlorides. 3900-89-8, formula is C6H6BClO2, Name is (2-Chlorophenyl)boronic acid. Their wide structural variety and divergent chemical properties lead to a broad range of named reactions and applications. Computed Properties of 3900-89-8.
Fan, Lingling;Luo, Zhongfu;Yang, Changfei;Guo, Bing;Miao, Jing;Chen, Yang;Tang, Lei;Li, Yong research published 《 Design and synthesis of small molecular 2-aminobenzoxazoles as potential antifungal agents against phytopathogenic fungi》, the research content is summarized as follows. In order to discover novel antifungal agents, three series of simple 2-aminobenzoxazole derivatives I (R = H, NO2, Ph, 2-benzothienyl, etc.; R1 = NH2, acetamidyl, benzenesulfonamido, etc.) were designed, synthesized and evaluated for their antifungal activities against eight phytopathogenic fungi. The in vitro antifungal results showed that most of the target compounds exhibited excellent and broad-spectrum antifungal activities to all the tested fungi. Particularly, the six compounds I (R = Ph, 2-fluorophenyl, 4-fluorophenyl, 3-chlorophenyl, 3,5-dimethylphenyl, 3-thienyl; R1 = NH2) displayed the most potent antifungal activity, with EC50 value of 1.48-16.6μg/mL, which were much superior to the pos. control hymexazol. The in vivo study further confirmed that compounds I (R = Ph, 4-fluorophenyl, 3-chlorophenyl, 3,5-dimethylphenyl; R1 = NH2) displayed good preventative effect against Botrytis cinerea at the concentration of 100μg/mL. The structure-activity relationships research provides significant reference for the further structural optimization of 2-aminobenzoxazole as potential fungicides.
3900-89-8, 2-Chlorophenylboronic acid is a useful research compound. Its molecular formula is C6H6BClO2 and its molecular weight is 156.38 g/mol. The purity is usually 95%.
2-Chlorophenylboronic acid used in the preparation of imidazo[1,2-a]pyridine amides which has tuberculostatic activity.
2-Chlorophenylboronic acid is a diphenyl ether that can be used as a building block for the synthesis of benzodiazepine receptor ligands. It has been shown to be an efficient nucleophile, leading to the formation of carbonyl groups in the presence of halides. 2-Chlorophenylboronic acid has also been shown to inhibit p38 kinase activity and may be useful for anticancer therapy., Computed Properties of 3900-89-8
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics