Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 89794-02-5, name is 4-Bromo-2-chlorotoluene, This compound has unique chemical properties. The synthetic route is as follows., Safety of 4-Bromo-2-chlorotoluene
Example 3 Bis(4,4′-(3-chloro-4-methylphenylhydroxyboryl)benzyl) ether; [Show Image] Bis(4-bromobenzyl) ether (157 mg) was dissolved in 8 mL of ether, and the solution was cooled to -78C. After addition of 2 mL of a 1 M sec-BuLi solution, the mixture was stirred for two hours (solution A). 4-Bromo-2-chlorotoluene (205 mg) was dissolved in 8 mL of ether, and the solution was cooled to -90C. After addition of 2 mL of a 1 M sec-BuLi solution, the mixture was stirred for two hours. Triisopropoxyborane (0.46 mL) was added to the resulting solution, and the mixture was stirred for 1.5 hours. The solution A was added to the solution, and the mixture was gradually returned to room temperature and stirred overnight. Aqueous dilute hydrochloric acid was added, and the mixture was stirred. The organic layer was dried and then concentrated and applied to a silica gel column to give 77 mg of the entitled compound as a grease. Rf= 0.48 (EtOAc, Hexane 1: 1) NMR (CDCl3) 2.35 (s, 6H), 4.53 (s, 4H), 7.1-8.2 (m, 14H)
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 89794-02-5.
Reference:
Patent; Japan Science and Technology Agency; EP1961756; (2008); A1;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics