The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 2-((1R,5S)-6,6-Dimethylbicyclo[3.1.1]hept-2-en-2-yl)ethanol( cas:35836-73-8 ) is researched.Category: chlorides-buliding-blocks.Gu, Jia-Yi; Zhang, Wei; Jackson, Seth R.; He, Yan-Hong; Guan, Zhi published the article 《Photoinduced umpolung addition of carbonyl compounds with α,β-unsaturated esters enables the polysubstituted γ-lactone formation》 about this compound( cas:35836-73-8 ) in Chemical Communications (Cambridge, United Kingdom). Keywords: unsaturated ester carbonyl compound iridium photocatalyst umpolung addition transesterification; aryl lactone diastereoselective preparation. Let’s learn more about this compound (cas:35836-73-8).
The photoinduced intermol. umpolung addition of aromatic ketones/aldehydes with α,β-unsaturated esters via ketyl radical intermediates was reported. Following an intramol. transesterification, a variety of γ-lactone derivatives were readily accessed. Mechanistic investigations demonstrated the significant role of Hantzsch ester, which served both as the electron and proton donor.
As far as I know, this compound(35836-73-8)Category: chlorides-buliding-blocks can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.
Reference:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics