In 2020.0 TETRAHEDRON published article about C-H ACTIVATION; CATALYZED OXIDATION; PRIMARY ALCOHOLS; ALDEHYDES; AMINES; BOND; BENZAMIDES; ESTERS; AROYLATION; CHEMISTRY in [Shi, Tingting; Yang, Yuhang; He, Wei; Liu, Chengkou; Fang, Zheng] Nanjing Tech Univ, Coll Biotechnol & Pharmaceut Engn, 30 Puzhu Rd S, Nanjing 211816, Peoples R China; [Shi, Tingting] Bengbu Med Coll, Dept Chem, Bengbu 233030, Peoples R China; [Zhang, Zhimin] Changzhou Yabang Pharmaceut Co LTD, Changzhou 213200, Peoples R China; [Yang, Zhao] China Pharmaceut Univ, Sch Engn, 639 Longmian Ave, Nanjing 211198, Peoples R China; [Guo, Kai] Nanjing Tech Univ, State Key Lab Mat Oriented Chem Engn, 30 Puzhu Rd S, Nanjing 211816, Peoples R China in 2020.0, Cited 55.0. The Name is 1-Chloro-2-methylbenzene. Through research, I have a further understanding and discovery of 95-49-8. Name: 1-Chloro-2-methylbenzene
A green and efficient method for the synthesis of amides has been developed through oxidative amidation between methylarenes with amines in a two-step continuous flow system. This method integrates methylarene oxidation and amide formation into a single operation which is usually accomplished separately. Oxidation with tert-butyl hydroperoxide (TBHP) as green oxidant, the synthesis of amides under mild reaction conditions in continuous flow system and the utilization of methylarenes as starting material make this methodology novel and environment friendly. The practical value of this method is highlighted through the synthesis of high-profile pharmaceutical agents, acetylprocainamide. (C) 2020 Elsevier Ltd. All rights reserved.
About 1-Chloro-2-methylbenzene, If you have any questions, you can contact Shi, TT; Zhang, ZM; Yang, YH; Yang, Z; He, W; Liu, CK; Fang, Z; Guo, K or concate me.. Name: 1-Chloro-2-methylbenzene
Reference:
Patent; Nanjing Zhongteng Chemical Co., Ltd.; Zhong Hua; Lu Minshan; Chen Xiuzhen; Liu Qiaobao; Yin Hengbo; Wang Aili; (8 pag.)CN104876790; (2017); B;,
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