Application In Synthesis of 1-Chloro-2-methylbenzene. Recently I am researching about RADICAL-ADDITION; C-N; LIGHT; BROMOTRICHLOROMETHANE; FUNCTIONALIZATION; TRANSFORMATIONS; MECHANISM; TOLUENE; FUTURE; BOND, Saw an article supported by the Austrian Federal Ministry of Transport, Innovation and Technology (BMVIT) [862766]; Austrian Federal Ministry of Science, Research and Economy (BMWFW); State of Styria (Styrian Funding Agency SFG). Published in ROYAL SOC CHEMISTRY in CAMBRIDGE ,Authors: Otake, Y; Williams, JD; Rincon, JA; de Frutos, O; Mateos, C; Kappe, CO. The CAS is 95-49-8. Through research, I have a further understanding and discovery of 1-Chloro-2-methylbenzene
BrCCl3 represents a rarely used benzylic brominating reagent with complementary reactivity to other reagents. Its reactivity has been revisited in continuous flow, revealing compatibility with electron-rich aromatic substrates. This has brought about the development of a p-methoxybenzyl bromide generator for PMB protection, which was successfully demonstrated on a pharmaceutically relevant intermediate on 11 g scale, giving 91% yield and a PMB-Br space-time-yield of 1.27 kg L-1 h(-1).
Application In Synthesis of 1-Chloro-2-methylbenzene. About 1-Chloro-2-methylbenzene, If you have any questions, you can contact Otake, Y; Williams, JD; Rincon, JA; de Frutos, O; Mateos, C; Kappe, CO or concate me.
Reference:
Patent; Nanjing Zhongteng Chemical Co., Ltd.; Zhong Hua; Lu Minshan; Chen Xiuzhen; Liu Qiaobao; Yin Hengbo; Wang Aili; (8 pag.)CN104876790; (2017); B;,
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