In 2019.0 ORG LETT published article about MONO-ALPHA-ARYLATION; TRANSITION-METAL-FREE; REDUCTIVE ELIMINATION; (NHC)PD(ALLYL)CL NHC; ACETONE; COMPLEXES; HALIDES; AMIDES; ROUTE in [Hu, Xiao-Qiang; Lichte, Dominik; Weber, Philip; Seitz, Ann-Katrin; Goossen, Lukas J.] Ruhr Univ Bochum, Evonik Chair Organ Chem, Fac Chem & Biochem, Univ Str 150, D-44801 Bochum, Germany; [Rodstein, Ilja; Scherpf, Thorsten; Gessner, Viktoria H.] Ruhr Univ Bochum, Chair Inorgan Chem 2, Fac Chem & Biochem, Univ Str 150, D-44801 Bochum, Germany; [Hu, Xiao-Qiang] South Cent Univ Nationalities, Minist Educ, Key Lab Catalysis & Mat Sci, Wuhan 430074, Hubei, Peoples R China in 2019.0, Cited 49.0. The Name is 1-Chloro-2-methylbenzene. Through research, I have a further understanding and discovery of 95-49-8. Quality Control of 1-Chloro-2-methylbenzene
Ylide-functionalized phosphine (YPhos) ligands allow the palladium-catalyzed alpha-arylation of alkyl ketones with aryl chlorides with record setting activity. Using a cyclohexyl-substituted YPhos ligand, a wide range of challenging ketone substrates was efficiently and selectively monoarylated under mild conditions. A newly designed YPhos ligand bearing tert-butyl groups on the coordinating phosphorus atom is already active at room temperature. The synthetic potential was demonstrated by gram-scale reactions and the succinct synthesis of epsilon-caprolactone derivatives.
Quality Control of 1-Chloro-2-methylbenzene. About 1-Chloro-2-methylbenzene, If you have any questions, you can contact Hu, XQ; Lichte, D; Rodstein, I; Weber, P; Seitz, AK; Scherpf, T; Gessner, VH; Goossen, LJ or concate me.
Reference:
Patent; Nanjing Zhongteng Chemical Co., Ltd.; Zhong Hua; Lu Minshan; Chen Xiuzhen; Liu Qiaobao; Yin Hengbo; Wang Aili; (8 pag.)CN104876790; (2017); B;,
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