Adding a certain compound to certain chemical reactions, such as: 2533-69-9, name is Methyl 2,2,2-trichloroacetimidate, belongs to chlorides-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 2533-69-9, HPLC of Formula: C3H4Cl3NO
A mixture of 1.98 g of 4-trifluoromethylbenzene-1, 2-diamine and 15 ml of acetic acid was added to a mixture of1.98 g of methyl-2,2,2-trichloroacetimidate and 15 ml of acetic acid under ice cooling, followed by stirring for 3 hours at room temperature. The reaction mixture was concentrated under reduced pressure, ethyl acetate was added to the residues, and the resultant was washed with an aqueous saturated sodium hydrogen carbonate solution and saturated saline. The organic layer was dried over magnesium sulfate and then concentrated under reduced pressure, thereby obtaining 3.39 g of 2-trichioromethyl-5-trifluoromethylbenzimidazole. 1H-NMR (DMSO-D5) oe: 8.18-8.00 (m, 1H), 7.94-7.80 (m, 1H), 7.72-7.65 (m, 1H)
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, Methyl 2,2,2-trichloroacetimidate, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; SUMITOMO CHEMICAL COMPANY, LIMITED; Mukumoto, Fujio; Tamaki, Hiroaki; Kusaka, Shintaro; Iwakoshi, Mitsuhiko; US2015/289512; (2015); A1;,
Chloride – Wikipedia,
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