Carbon Dioxide-Catalyzed Stereoselective Cyanation Reaction was written by Roy, Tamal;Kim, Myungjo J.;Yang, Yang;Kim, Suyeon;Kang, Gyumin;Ren, Xinyi;Kadziola, Anders;Lee, Hee-Yoon;Baik, Mu-Hyun;Lee, Ji-Woong. And the article was included in ACS Catalysis in 2019.COA of Formula: C9H9ClO2 This article mentions the following:
We report a Michael-type cyanation reaction of coumarins by using CO2 as a catalyst. The delivery of the nucleophilic cyanide was realized by catalytic amounts of CO2, which forms cyanoformate and bicarbonate in the presence of water. Under ambient conditions, CO2-catalyzed reactions afforded high chemo- and diastereoselectivity of β-nitrile carbonyls, whereas only low reactivities were observed under argon or N2. Computational and exptl. data suggest the catalytic role of CO2, which functions as a Lewis acid, and a protecting group to mask the reactivity of the product, suppressing byproducts and polymerization The utility of this convenient method was demonstrated by preparing biol. relevant heterocyclic compounds with ease. In the experiment, the researchers used many compounds, for example, 2-(3-Methoxyphenyl)acetyl chloride (cas: 6834-42-0COA of Formula: C9H9ClO2).
2-(3-Methoxyphenyl)acetyl chloride (cas: 6834-42-0) belongs to organic chlorides. An organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst.COA of Formula: C9H9ClO2
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics