Palladium-catalyzed aminocarbonylative cyclization of benzyl chlorides with 2-nitroaryl alkynes to construct indole derivatives was written by Wang, Qi;Yao, Lingyun;Wang, Jian-Shu;Ying, Jun;Wu, Xiao-Feng. And the article was included in Molecular Catalysis in 2022.HPLC of Formula: 620-19-9 This article mentions the following:
A palladium-catalyzed aminocarbonylative cyclization of benzyl chlorides RCH2Cl (R = Ph, 3,5-dichlorophenyl, naphthalen-1-yl, etc.) with 2-nitroaryl alkynes 2-NO2-4-R1-5-R2C6H2CCR3 (R1 = H, Me, F; R2 = H, Cl; R3 = Ph, n-Bu, cyclopropyl, etc.) has been developed for the rapid construction of indole skeletons I. The reaction utilized nitroarenes as the nitrogen source, Mo(CO)6 as both the CO surrogate and the reductant to furnish various indole derivatives I in moderate to high yields. In the experiment, the researchers used many compounds, for example, 1-(Chloromethyl)-3-methylbenzene (cas: 620-19-9HPLC of Formula: 620-19-9).
1-(Chloromethyl)-3-methylbenzene (cas: 620-19-9) belongs to organic chlorides. Organochlorines stimulate the central nervous system and cause convulsions, tremor, nausea, and mental confusion. Examples are dichlorodiphenyltrichloroethane (DDT), chlordane, lindane, endosulfan, and dieldrin. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst.HPLC of Formula: 620-19-9
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics