Singh, Santosh Kumar et al. published their research in International Journal of Green and Herbal Chemistry in 2013 | CAS: 14070-51-0

2-Chlorobenzo[d]isothiazol-3(2H)-one 1,1-dioxide (cas: 14070-51-0) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. Organochlorine compounds are lipophylic, meaning they are more soluble in fat than in water. This gives them a high tenancy to accumulate in the food chain (biomagnification).Safety of 2-Chlorobenzo[d]isothiazol-3(2H)-one 1,1-dioxide

Mechanistic investigation of oxidation of metronidazole with N-chlorosaccharin in acid medium: a kinetic approach was written by Singh, Santosh Kumar;Khan, M. U.;Dwivedi, H. P.;Chauhan, D. B. S.;Gupta, H. D.. And the article was included in International Journal of Green and Herbal Chemistry in 2013.Safety of 2-Chlorobenzo[d]isothiazol-3(2H)-one 1,1-dioxide This article mentions the following:

A kinetic study of oxidation of Mitronidazole (MTZ) is an anti-bacterial and anti-protozoal drug, with N-chlorosaccharin (NCSA) has been carried out in presence of HClO4 in aqueous acetic acid medium at 308 K. The reaction is fully HClO4 acid catalyzed and retardation was observed when saccharin was added in reaction mixture Variation of ionic strength of the medium shows negligible effect on rate of reaction. Increase in dielec. permittivity of the medium increases the rate of oxidation The stoichiometry of the reaction was found to be 1:1. The reported oxidation product of MTZ was identified as the 2-methyl-5-nitro imidazole-N1-acetaldehyde which was detected by conventional methods and spot test. Various activation parameters have been evaluated. The reaction constants involved in the proposed mechanisms were computed. The proposed mechanisms were in good consistent with the observed exptl. results. In the experiment, the researchers used many compounds, for example, 2-Chlorobenzo[d]isothiazol-3(2H)-one 1,1-dioxide (cas: 14070-51-0Safety of 2-Chlorobenzo[d]isothiazol-3(2H)-one 1,1-dioxide).

2-Chlorobenzo[d]isothiazol-3(2H)-one 1,1-dioxide (cas: 14070-51-0) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. Organochlorine compounds are lipophylic, meaning they are more soluble in fat than in water. This gives them a high tenancy to accumulate in the food chain (biomagnification).Safety of 2-Chlorobenzo[d]isothiazol-3(2H)-one 1,1-dioxide

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics