Synthesis of macrosporin and related 9,10-anthraquinones by biomimetic polyketide aromatization and cyclization of 6-benzylresorcylates was written by Cordes, Jens;Barrett, Anthony G. M.. And the article was included in European Journal of Organic Chemistry in 2013.Recommanded Product: 2-(3-Methoxyphenyl)acetyl chloride This article mentions the following:
The synthesis of an array of 1-hydroxy-3-methoxy-9,10-anthraquinones by initial preparation of 6-benzylresorcylates from oxo-dioxinone precursors and their subsequent conversion to anthrones by cyclization and oxidn was described. The resorcylates were obtained by an improved 2-step procedure from 6-(4-allyloxy-2,4-dioxobutyl)-2,2-dimethyl-2,4-dihydro-1,3-dioxin-4-one and benzeneacetyl chlorides. These methods were applied in a 7-step synthesis of the fungal natural product macrosporin. In the experiment, the researchers used many compounds, for example, 2-(3-Methoxyphenyl)acetyl chloride (cas: 6834-42-0Recommanded Product: 2-(3-Methoxyphenyl)acetyl chloride).
2-(3-Methoxyphenyl)acetyl chloride (cas: 6834-42-0) belongs to organic chlorides. Organochlorines stimulate the central nervous system and cause convulsions, tremor, nausea, and mental confusion. Examples are dichlorodiphenyltrichloroethane (DDT), chlordane, lindane, endosulfan, and dieldrin.While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.Recommanded Product: 2-(3-Methoxyphenyl)acetyl chloride
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics