Silver-promoted (radio)fluorination of unsaturated carbamates via a radical process was written by Yang, Bin;Chansaenpak, Kantapat;Wu, Hongmiao;Zhu, Lin;Wang, Mengzhe;Li, Zibo;Lu, Hongjian. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2017.Application In Synthesis of tert-Butyl (4-chlorophenyl)carbamate This article mentions the following:
The intramol. fluorocyclization of unsaturated carbamates is described here using a hypervalent iodine reagent in the presence of a silver catalyst. Both (hetero)aryl-substituted olefins and acrylamides can be utilized as effective substrates. Preliminary mechanistic investigations suggest that the reaction proceeds via a cyclization/1,2-(hetero)aryl migration/fluorination cascade involving an unusual radical process. Furthermore, starting from no-carrier-added [18F]TBAF, a simple one-pot, two-step cascade method was developed for the generation of 18F-labeled heterocycles with high radiochem. purity. In the experiment, the researchers used many compounds, for example, tert-Butyl (4-chlorophenyl)carbamate (cas: 18437-66-6Application In Synthesis of tert-Butyl (4-chlorophenyl)carbamate).
tert-Butyl (4-chlorophenyl)carbamate (cas: 18437-66-6) belongs to organic chlorides. Organic chlorides can be used in production of: PVC, pesticides, chloromethane, teflon, insulators. Alkyl chlorides readily react with amines to give substituted amines. Alkyl chlorides are substituted by softer halides such as the iodide in the Finkelstein reaction.Application In Synthesis of tert-Butyl (4-chlorophenyl)carbamate
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics