Installation of protected ammonia equivalents onto aromatic & heteroaromatic rings in water enabled by micellar catalysis was written by Isley, Nicholas A.;Dobarco, Sebastian;Lipshutz, Bruce H.. And the article was included in Green Chemistry in 2014.Computed Properties of C11H14ClNO2 This article mentions the following:
A single set of conditions consisting of a palladium catalyst, a com. available ligand, and a base allow for several types of C-N bond constructions to be conducted in water with the aid of a com. available “designer” surfactant (TPGS-750-M). Products containing a protected NH2 group in the form of a carbamate, sulfonamide, or urea can be fashioned starting with aryl or heteroaryl bromides, iodides, and in some cases, chlorides, as substrates. Reaction temperatures are in the range of room temperature to, at most, 50 °C, and result in essentially full conversion and good isolated yields. E.g., in presence of allylpalladium chloride dimer, a ligand, and TPGS-750-M in water, amidation of 4-BrC6H4CO2Et with carbamate H2NCO2Et gave 99% I. In the experiment, the researchers used many compounds, for example, tert-Butyl (4-chlorophenyl)carbamate (cas: 18437-66-6Computed Properties of C11H14ClNO2).
tert-Butyl (4-chlorophenyl)carbamate (cas: 18437-66-6) belongs to organic chlorides. An organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control.Computed Properties of C11H14ClNO2
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics