Synthesis and herbicidal activities of novel 4-(3-trifluoromethylphenyl)-2H-pyridazin-3-one derivatives was written by Xu, Han;Hu, Xu Hong;Zhu, You Quan;Zou, Xiao Mao;Liu, Bin;Hu, Fang Zhong;Yang, Hua Zheng. And the article was included in Science China: Chemistry in 2010.Computed Properties of C7H5ClF2 This article mentions the following:
Three series of forty-nine novel 4-(3-trifluoromethylphenyl)-2H-pyridazin-3-one derivatives are designed, synthesized, and evaluated through a Spirodela polyrrhiza test and a greenhouse test. Some compounds show > 80% chlorophyll inhibition of Spirodela polyrrhiza at 10 μg/mL and exhibit some herbicidal activities against Digitaria adscendens in the preemergence treatment at a rate of 150 g/ha. Moreover, the study of the structure-activity relationship (SAR) suggests that the appropriate bulky substituent at the right position is critical for the bleaching and herbicidal activities, which may be useful for the future design of new compounds In the experiment, the researchers used many compounds, for example, 2-(Chloromethyl)-1,3-difluorobenzene (cas: 697-73-4Computed Properties of C7H5ClF2).
2-(Chloromethyl)-1,3-difluorobenzene (cas: 697-73-4) belongs to organic chlorides. Organic chlorides can be used in production of: PVC, pesticides, chloromethane, teflon, insulators.While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.Computed Properties of C7H5ClF2
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics