Alkylation of enaminoketone with a modified carane skeleton. Formation of stable β-diketone monoimines was written by Tkachev, A. V.;Popov, S. A.. And the article was included in Russian Journal of Organic Chemistry (Translation of Zhurnal Organicheskoi Khimii) in 1997.COA of Formula: C7H5ClF2 This article mentions the following:
Alkylation of a bicyclic enaminoketone, 1-[(1R,5R)-3-amino-6,6-dimethylbicyclo[3.1.0]hex-2-en-2-yl]ethanone, with highly reactive alkyl halides (Me iodide, benzyl halides, and allyl halides) in a two-phase system benzene-40% aqueous NaOH in the presence of benzyltriethylammonium chloride (BTEA) as phase-transfer catalyst results in formation of stable β-diketone monoimines, derivatives of the series of 1-[(1R,5R)-2-alkyl-3-imino-6,6-dimethylbicyclo[3.1.0]hex-2-yl]ethanone, in 53-81% yields. In the experiment, the researchers used many compounds, for example, 2-(Chloromethyl)-1,3-difluorobenzene (cas: 697-73-4COA of Formula: C7H5ClF2).
2-(Chloromethyl)-1,3-difluorobenzene (cas: 697-73-4) belongs to organic chlorides. Organochlorines stimulate the central nervous system and cause convulsions, tremor, nausea, and mental confusion. Examples are dichlorodiphenyltrichloroethane (DDT), chlordane, lindane, endosulfan, and dieldrin. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst.COA of Formula: C7H5ClF2
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics