Arylsulfonamidotetralin inhibitors of the Kv1.5 ion channel was written by Gross, Michael F.;Castle, Neil A.;Zou, Anruo;Wickenden, Alan D.;Yu, Weifeng;Spear, Kerry L.. And the article was included in Bioorganic & Medicinal Chemistry Letters in 2009.Recommanded Product: 2-(3-Methoxyphenyl)acetyl chloride This article mentions the following:
Arylsulfonamidotetralins based on lead compound I were synthesized and evaluated for Kv1.5 inhibitory activity. Several compounds having IC50 values less then 0.1 μM were identified. Kv1.5 inhibitors have the potential to be atrium-selective agents for the treatment of atrial fibrillation. In the experiment, the researchers used many compounds, for example, 2-(3-Methoxyphenyl)acetyl chloride (cas: 6834-42-0Recommanded Product: 2-(3-Methoxyphenyl)acetyl chloride).
2-(3-Methoxyphenyl)acetyl chloride (cas: 6834-42-0) belongs to organic chlorides. Chlorination modifies the physical properties of hydrocarbons in several ways. These compounds are typically denser than water due to the higher atomic weight of chlorine versus hydrogen. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst.Recommanded Product: 2-(3-Methoxyphenyl)acetyl chloride
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics