Dissociation constants of organic acids was written by Kendall, J.. And the article was included in Med. Vetenskaps. Nobelinst. in 1914.Name: 3-Chloro-5-nitrobenzoic acid This article mentions the following:
The apparatus and method have been previously described (C. A., 6, 3043). K.’s value for H+ ion at 25°, Λ0 = 347.2 was used. The expression m2/(1-m)v = k + c(1-m)/m, (1), where k and c are constants for a particular acid, expresses the results of the previous work. The conductivity of HOAc at 25° was means. from N to 0.0005 N. The value of (k + c(1-m)/m) = K’ increased with the dilution up to v = 16, after which it was 1.84 × 10-5. HOAc is such a weak acid that the value of the constant c in eq. (1) is negligibly small. For HCOOCH2CN Λ0 = 398.2 and K’ = 3.91 to 3.69 × 10-3 between 0.03 N and 0.0002 N. For KCOOCHCl2 Λ0 = 112.9 and K’ for the acid changes with the concentrate from 0.0933 at N to 0.0490 at 0.002 N; for KCOOCCl3, Λ0 = 111.2 and K’ for the acid changes from 0.423 to 0.091 between N and 0.002 N. Here the acids are so strong that values of k and c in equation (1) cannot be calculate For trichlorobutyric acid Λ0 = 376.0, K’ = 0.148 at 0.03 N to 0.0102 at 0.002 N; o-chlorobenzoic acid, Λ0 = 380.0; K’ = 1.288 to 1.281 × 10-2 from 0.0006 N to 0.0002 N; o-nitrobenzoic acid, Λ0 = 379.4, K’ = 6.75 to 6.21 × 10-2 between 0.03 N and 0.002 N; m,m-dinitrobenzoic acid, Λ0 = 376.3, K’ = 1.57 × 10-2; m-chloro-m-nitrobenzoic acid, K’ = 7.48 × 10-4. Good agreement is found between eq. (1) and the observed values, but the exact theoretical significance of the equation does not seem to be apparent. The value Λ0 = 380.2 is given for salicylic acid, but the value of K’ does not become constant, even at 0.0002 N, probably on account of the diss. of the second H+ ion. For 5-bromosalicylic acid K’ goes through a minimum about 0.002 N, then increases as the dilution proceeds. A similar increase was found at the lower concentrate for 1,2,4-hydroxysalicylic acid, ?-1-2-4-bromohydroxysalicylic acid, 1,2,5-hydroxysalicylic acid and ?-1-2-5-bromohydroxysalicylic acid. In the experiment, the researchers used many compounds, for example, 3-Chloro-5-nitrobenzoic acid (cas: 34662-36-7Name: 3-Chloro-5-nitrobenzoic acid).
3-Chloro-5-nitrobenzoic acid (cas: 34662-36-7) belongs to organic chlorides. Organochlorines stimulate the central nervous system and cause convulsions, tremor, nausea, and mental confusion. Examples are dichlorodiphenyltrichloroethane (DDT), chlordane, lindane, endosulfan, and dieldrin. Alkyl chlorides readily react with amines to give substituted amines. Alkyl chlorides are substituted by softer halides such as the iodide in the Finkelstein reaction.Name: 3-Chloro-5-nitrobenzoic acid
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics