The crystal structures of three disordered 2-substituted benzimidazole esters was written by Harish Chinthal, Chayanna;Yathirajan, Hemmige S.;Manju, Nagaraja;Kalluraya, Balakrishna;Foro, Sabine;Glidewell, Christopher. And the article was included in Acta Crystallographica, Section E: Crystallographic Communications in 2021.Application In Synthesis of Ethyl 4-chloro-3-nitrobenzoate This article mentions the following:
The crystal structures of three benzimidazole esters containing aryl or heterocyclic substituents at position 2 are reported, and all three exhibit disorder of mol. entities. In Et 1-methyl-2-[4-(prop-2-ynoxy)phenyl]-1H-benzimidazole-5-carboxylate, C20H18N2O3, (I), the prop-2-yn-1-oxyphenyl unit is disordered over two sets of at. sites having effectively equal occupancies, 0.506 (5) and 0.494 (5). The Pr substituent in Et 1-propyl-2-(pyren-1-yl)-1H-benzimidazole-5-carboxylate, C29H24N2O2, (II), is disordered over two sets of at. sites having occupancies 0.601 (8) and 0.399 (8), and the ester unit in Et 1-methyl-2-(5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)-1H-benzimidazole-5-carboxylate, C21H19ClN4O2 (III), is disordered over two sets of at. sites having occupancies 0.645 (7) and 0.355 (7). In each of the C-H···π(arene) hydrogen bonds in (I), the donor and acceptor form parts of different disorder components, so that no continuous aggregation is possible. The mols. of (II) are linked by a single C-H···O hydrogen bond into C(10) chains, which are linked into sheets by a π-π stacking interaction, whereas those of (III) are just linked into C(13) chains, again by a single C-H···O hydrogen bond. Comparisons are made with the structures of some related compounds In the experiment, the researchers used many compounds, for example, Ethyl 4-chloro-3-nitrobenzoate (cas: 16588-16-2Application In Synthesis of Ethyl 4-chloro-3-nitrobenzoate).
Ethyl 4-chloro-3-nitrobenzoate (cas: 16588-16-2) belongs to organic chlorides. Organic chlorides can be used in production of: PVC, pesticides, chloromethane, teflon, insulators. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control.Application In Synthesis of Ethyl 4-chloro-3-nitrobenzoate
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