Crystal structures of salts and cocrystal of 1,3,5-triazine derivatives with thiophene carboxylic acid derivatives: an investigation on supramolecular interactions was written by Prajina, O. K.;Muthiah, P. T.;Perdih, F.. And the article was included in SN Applied Sciences in 2019.Reference of 36157-41-2 This article mentions the following:
Present work gives an account of different types of non covalent interactions encountered in the supramol. architectures of new salts and cocrystal formed between derivatives of 1,3,5-triazine and thiophene carboxylic acid. The novel salts formed between derivatives of thiophene carboxylic acid and 1,3,5-triazine are 2, 4-diamino-6-methyl-1,3,5-triazin-1-ium 5-carboxythiophene-2-carboxylate monohydrate, C4H8N5+·C6H3O4S1–·H2O (I) and 2,4-diamino-6-methyl-1,3,5-triazin-1-ium 3-bromothiophene-2-carboxylate monohydrate, C4H8N5+·C5H2O2S1Br1–·H2O (II). The new cocrystal is a 1:1 cocrystal formed between 2,4-diamine-6-phenyl-1,3,5-triazine and 2,5-dichlorothiophene-3-carboxylic acid, C9H9N5·C5H2O2S1Cl2 (III). The newly synthesized salts (I and II) and cocrystal (III) have been characterized by single-crystal X-ray diffraction. Supramol. heterosynthons, homosynthons observed via N-H···O, N-H···N and O-H···N hydrogen bonds are also discussed. Anion···π interaction between carboxylate oxygen and aromatic rings of thiophene and triazine are observed in salt (I). π···π interaction is present between thiophene and triazine rings in salt (II). R22(8) ring motif is formed in cocrystal (III) via N-H···O and O-H···N hydrogen bonds. Further stabilization of cocrystal (III) via Cl···O, Cl···Cl interactions as well as π···π interactions (triazine···triazine rings and triazine···phenyl rings) are also investigated. In the experiment, the researchers used many compounds, for example, 2,5-Dichlorothiophene-3-carboxylic acid (cas: 36157-41-2Reference of 36157-41-2).
2,5-Dichlorothiophene-3-carboxylic acid (cas: 36157-41-2) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.Reference of 36157-41-2
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics