A Bi(OTf)3-Promoted Hydrosulfonylation of Alkenes with Sulfonyl Hydrazides: An Approach to Branched Sulfones was written by Zhou, Zheng;Liu, Qianqian;Huang, Zhibin;Zhao, Yingsheng. And the article was included in Organic Letters in 2022.Category: chlorides-buliding-blocks This article mentions the following:
The Bi(OTf)3-promoted hydrosulfonylation of alkenes with sulfonyl hydrazides to produce branched sulfones was reported, in which various branched sulfones (â?0 examples) were prepared in moderate to good yields. The gram-scale reaction and synthesis of the exptl. inhibitor precursor showed the potential application. A preliminary mechanistic study revealed that double-bond migration to form the α,β-conjugated alkene is crucial for this transformation. In the experiment, the researchers used many compounds, for example, 3-(Trifluoromethyl)benzene-1-sulfonyl chloride (cas: 777-44-6Category: chlorides-buliding-blocks).
3-(Trifluoromethyl)benzene-1-sulfonyl chloride (cas: 777-44-6) belongs to organic chlorides. Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. The hydrocarbon processing industry (HPI) and others are affected by damage caused by these substances. Alkyl chlorides are versatile building blocks in organic chemistry. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available.Category: chlorides-buliding-blocks
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics