Pd-catalyzed microwave irradiated regioselective aroylation reaction of crotyl- and allyltrifluoroborates was written by Al-Masum, Mohammad;Legan, Sarah;Liu, Kwei-Yu. And the article was included in International Journal of Organic Chemistry in 2016.SDS of cas: 1711-11-1 This article mentions the following:
An interesting regioselectivity is observed when the mixture of potassium crotyltrifluoroborate and aroyl chlorides RC(O)Cl (R = 3,4,6-trifluorophenyl, naphth-2-yl, 4-bromophenyl, etc.) having electron-deficient and electron-rich groups is microwaved in the presence of palladium-catalyst. In the case of electron withdrawing group with Ph ring of aroyl chlorides, isomerized α,β-unsaturated compound RC(O)CH(CH3)=CHCH3 is a product, whereas the electron donating group with Ph ring of aroyl chlorides furnishes α-adduct RC(O)CH(CH3)CH=CH2. Similar aroylation reaction is also established for potassium allyltrifluoroborate. In this case, regioselectivity is unaffected with changing electron-rich or electron-deficient groups in Ph ring of the aroyl chlorides. Reactions proceed with, essentially in same rate, to afford the corresponding aryl propenyl ketones (crotonophenones) RC(O)CH=CHCH3 in good to high yields. In the experiment, the researchers used many compounds, for example, 3-Cyanobenzoyl chloride (cas: 1711-11-1SDS of cas: 1711-11-1).
3-Cyanobenzoyl chloride (cas: 1711-11-1) belongs to organic chlorides. Organochlorines stimulate the central nervous system and cause convulsions, tremor, nausea, and mental confusion. Examples are dichlorodiphenyltrichloroethane (DDT), chlordane, lindane, endosulfan, and dieldrin. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst.SDS of cas: 1711-11-1
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics