GC-MS analysis of bioactive components in the methanolic extract of graviola (Gishta) seeds and their pharmacological activities was written by Saripalli, Harikrishna Ramaprasad;Dixit, Prasanna Kumar. And the article was included in International Journal of Pharma and Bio Sciences in 2021.COA of Formula: C18H37Cl This article mentions the following:
Bioactive substances are the leading-edge mols. in both the pharmaceutical and nutraceutical industries. Recently, bioactive compounds are gaining much importance for their enhanced resistance to numerous diseases and in boosting people′s health by both traditional and modern ways of administration. In traditional medicine, many plants have provided valuable clues for being used as potential antiparasitic, antimalarial, leishmanicidal, anti-tumor, fungicidal, and antibacterial compounds Still, several plants are yet to be screened for their abilities to stand forth as medicinal plants. Locally, Graviola (Gishta) fruits are being used for dietary purposes and traditional medicinal purposes, but their beneficial effects have never been attributed to the presence of active bio compounds Hence, the present investigation was undertaken to study Gas Chromatog.-Mass Spectrometry (GC-MS) anal. of methanolic extracts of Graviola seeds. GC-MS anal. method was employed with specific conditions such as Ion source temp 200°C, Interface temp 240°C, Scan range 40 – 1000 m/z, MS start time 5(min), MS end time 35 (min), Ionization EI (-70ev), Scan speed 2000. The methanolic extracts of Graviola seeds exhibited the presence of seventy types of bioactive compounds The foremost important compounds identified are 1H-Cyclopenta [l, 3] cyclopropa [l, 2] benzene, octa hydro-7-methyl-3-methylene-4-(1-Me ethyl) -, [3aS-(3a. alpha.,3b. beta., 4. beta., 7. alpha.,7 aS*)]-Bicyclo [4. 4. 0] dec-1-ene, 2-isopropyl-5-methyl-9-methylene-. gamma.-Muurolene. tetracosane, phytol and squalene. In an exceeding mass spectral view, each of the compounds has been identified based on their retention time and percentage of peak area(s). Analytes with high peak areas showed various pharmacol. properties such as antibacterial, antifungal, anticancer, etc. which provided exptl. evidence for its traditional medicinal claim. The spectra of phytochem. constituents found in the seed extracts signify the potential of the Graviola plant as a source of therapeutic agent(s) and may provide leads in the ongoing search for a novel phytotherapeutic agent. In the experiment, the researchers used many compounds, for example, 1-Chlorooctadecane (cas: 3386-33-2COA of Formula: C18H37Cl).
1-Chlorooctadecane (cas: 3386-33-2) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.COA of Formula: C18H37Cl
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics