Synthesis and pharmacological evaluation of novel 1-(2, 6- difluorobenzyl)-1h-1, 2, 3-triazole derivatives for Cns depressant and anticonvulsant profile was written by Shukla, Jagdish D.;Ali Khan, Pathan Arif Md.;Deo, Keshav. And the article was included in American Journal of PharmTech Research in 2015.Application of 697-73-4 This article mentions the following:
A series of 1-(2, 6-difluorobenzyl)-1H-1, 2, 3-triazole (5a-d and 7a-d) were synthesized and evaluated for CNS depressant and anticonvulsant activities by photoactometer, rotarod and pentylene tetrazole induced convulsion method resp. in Swiss albino mice. Diazepam was used as a standard drug. Out of the 8 compounds tested, compounds (5b, 7a and 7b) were showed the CNS depressant activity comparable to that of diazepam at a dose of 5 mg/kg. The active members of the series (5b, 7a and 7b) were selected for anticonvulsant activity study. In the experiment, the researchers used many compounds, for example, 2-(Chloromethyl)-1,3-difluorobenzene (cas: 697-73-4Application of 697-73-4).
2-(Chloromethyl)-1,3-difluorobenzene (cas: 697-73-4) belongs to organic chlorides. Organochlorines are organic compounds having multiple chlorine atoms. They were the first synthetic pesticides that were used in agriculture. They are resistant to most microbial and chemical degradations. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control.Application of 697-73-4
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics