Dawson, Thomas P.’s team published research in Journal of the American Chemical Society in 55 | CAS: 1002-41-1

Journal of the American Chemical Society published new progress about 1002-41-1. 1002-41-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is 1,2-Bis(2-chloroethyl)disulfane, and the molecular formula is C4H8Cl2S2, Synthetic Route of 1002-41-1.

Dawson, Thomas P. published the artcileReactions of certain halogen-substituted aryl, alkyl and dialkyl sulfides with benzylamines, Synthetic Route of 1002-41-1, the publication is Journal of the American Chemical Society (1933), 2070-5, database is CAplus.

The following sulfides, ClCH2CH2SR, are liquids of penetrating odor (R is given): Et, b47 63-5°, d425 1.0663, η × 103 (C. G. S. units at 25°) 9.89; Pr, b2 43-5°, d. 1.0349, η 12.92; Bu, b1 58-9°, d. 1.0122, η 15.25; iso-Am, b1 68°, d. 0.9899, η 18.55; Ph, b0.637 88-9°, d. 1.1769, η 30.86, PhCH2, b1.01 113-5°, d. 1.1479, η 50.61; BrCH2CH2SEt, b6 57-8°, d. 1.3908, 15.55. MeCHClCH2SEt, b17 60°, d. 1.0265, 11.15; Cl(CH2)3SEt, b17 72°, d. 1.0427, η 13.30. (MeCHClCH2)2S, b7 94-5°, d. 1.1569, η 33; (ClCH2CH2CH2)2S, b7 111-2°, d. 1.1774, η 41.87. (ClCH2)2S, b11 51°, d. 1.4065, η 18.09. (ClC2H4)2S2, b10 124-7°, d420 1.3375, η 83.06. β-Chloroethyl α,β-dichlorovinyl sulfide, b4 79.5-80.5°, d420 1.4581, η 31.98. Et allyl sulfide, b. 115-6°, d420 0.8676, η 5.97. These sulfides were treated with PhCH2NH2 and Na2CO3 in absolute EtOH; the b. ps. are for the free bases, the m. ps. for the HCl salts: β-benzylaminoethyl Et sulfide, b13 162-4°, m. 214-5°; Pr derivative, b13 167-9°, m. 175°; Bu derivative, b13 172-230°, m. 152-3°; iso-Am derivative, b17 190-250°, m. 161-2°; Ph derivative, m. 152-3°; β-benzylaminopropyl Et sulfide, b11 157-8°, m. 115°; γ-isomer, b12 163-5°, m. 172°; 3-benzyl-1,3-thiazetidine, b16 175-85°, m. 201-3°; bis(β-benzylaminopropyl) sulfide, m. 239-40°; bis(β-benzylaminoethyl) disulfide, m. 269°; β-benzylaminoethyl α-(and β-)chlorovinyl sulfide, m. 211-2°; β-benzylaminoethyl α,β-dichlorovinyl sulfide, m. 174-6°. The results may be regarded as further substantiating the condensation theory of vesicant action but they entirely eliminate thiazane formation as an important factor and appear to demand a new limitation-that of a reactive halogen on the β-C atom.

Journal of the American Chemical Society published new progress about 1002-41-1. 1002-41-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is 1,2-Bis(2-chloroethyl)disulfane, and the molecular formula is C4H8Cl2S2, Synthetic Route of 1002-41-1.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics