Yuan, Dan’s team published research in Journal of Materials Chemistry B: Materials for Biology and Medicine in 4 | CAS: 42074-68-0

Yuan, Dan published the artcileThe enzyme-instructed assembly of the core of yeast prion Sup35 to form supramolecular hydrogels, Name: 2-Chlorotrityl chloride, the publication is Journal of Materials Chemistry B: Materials for Biology and Medicine (2016), 4(7), 1318-1323, database is CAplus and MEDLINE.

Based on the self-assembly capability of the core segment (GNNQQNY) of yeast prion Sup35, we design and synthesize a series of structurally related precursors for the enzymic formation of hydrogels. We found that, with the catalysis of alk. phosphatase, the precursor becomes a hydrogelator that self-assembles in water to form nanofibers with an average width less than ten nanometers. Interestingly, the introduction of an amyloid segment into a cytotoxic precursor (N’ffyp: D-1P) is able to abrogate the cytotoxicity of the precursor, making the resulting peptide cell compatible. This work contributes a new insight into the use of enzymes to form cell compatible hydrogels of peptide cross-β spine.

Journal of Materials Chemistry B: Materials for Biology and Medicine published new progress about 42074-68-0. 42074-68-0 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Benzyl chloride,Benzene, name is 2-Chlorotrityl chloride, and the molecular formula is C17H18N2O6, Name: 2-Chlorotrityl chloride.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics