Yue, Wen-Jun’s team published research in Journal of the American Chemical Society in 143 | CAS: 864725-22-4

Journal of the American Chemical Society published new progress about 864725-22-4. 864725-22-4 belongs to chlorides-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Chloride,Alkenyl,Benzene, name is 1,3-Dichloro-5-(3,3,3-trifluoroprop-1-en-2-yl)benzene, and the molecular formula is C12H10F2Si, Synthetic Route of 864725-22-4.

Yue, Wen-Jun published the artcileSite-Selective Defluorinative sp3 C-H Alkylation of Secondary Amides, Synthetic Route of 864725-22-4, the publication is Journal of the American Chemical Society (2021), 143(17), 6395-6400, database is CAplus and MEDLINE.

A site-selective defluorinative sp3 C-H alkylation of secondary amides that rapidly and reliably incorporates gem-difluoroalkene motifs into previously unfunctionalized sp3 sites was disclosed. This protocol was distinguished by its mild conditions, wide scope and exquisite site-selectivity, thus unlocking a new platform to introduce carbonyl isosteres at saturated hydrocarbon sites.

Journal of the American Chemical Society published new progress about 864725-22-4. 864725-22-4 belongs to chlorides-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Chloride,Alkenyl,Benzene, name is 1,3-Dichloro-5-(3,3,3-trifluoroprop-1-en-2-yl)benzene, and the molecular formula is C12H10F2Si, Synthetic Route of 864725-22-4.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics