Traceless Directing Groups in Radical Cascades: From Oligoalkynes to Fused Helicenes without Tethered Initiators was written by Pati, Kamalkishore;dos Passos Gomes, Gabriel;Harris, Trevor;Hughes, Audrey;Phan, Hoa;Banerjee, Tanmay;Hanson, Kenneth;Alabugin, Igor V.. And the article was included in Journal of the American Chemical Society in 2015.Recommanded Product: 1186603-47-3 The following contents are mentioned in the article:
We report the first example of a traceless directing group in a radical cascade. The chemo- and regioselectivity of the initial attack in skipped oligoalkynes is controlled by propargyl OR moiety [e.g., oligoalkyne I â?benzofluorene II (86%) using Bu3SnH + AIBN]. Radical translocations lead to the boomerang return of the radical center to the site of initial attack where it assists the elimination of the directing functionality via β-scission in the last step of the cascade. The Bu3Sn moiety continues further via facile reactions with electrophiles as well as Stille and Suzuki cross-coupling reactions. This selective radical transformation opens a new approach for the controlled transformation of skipped oligoalkynes into polycyclic ribbons of tunable dimensions. This study involved multiple reactions and reactants, such as 5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3Recommanded Product: 1186603-47-3).
5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3) belongs to organic chlorides. An organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control.Recommanded Product: 1186603-47-3
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Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics