Synthesis, characterization and antimicrobial activity of benzothiazoles and 1,3-oxazine based derivatives of s-triazine was written by Patel, T. V.;Malik, G. M.. And the article was included in Journal of Ultra Chemistry in 2018.Application In Synthesis of 4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine The following contents are mentioned in the article:
Some new substituted 1,3,5-triazine derivatives I [R = H, 4-COMe, 2-O2N-4-Cl, etc.] were synthesized by reacting with N2-(4-(benzo[d]thiazol-2-yl)phenyl)-6-chloro-N4-phenyl-1,3,5-triazine-2,4-diamines, which in-turn prepared from 4,6-dichloro-N-phenyl-1,3,5-triazin-2-amines (prepared from cyanuric chloride and primary amines) with 4(beno[d]thiazol-2-yl)aniline and 6-(4-methoxypheny1)-4-phenyl-2H-1,3-oxazin-2-amine and evaluated for their in-vitro antimicrobial activity against Gram pos. and Gram neg. strains using a micro dilution procedure. Synthesized compoundsI proved to be effective with MIC (μg/mL), among them I [R = 4-Br, 4-Me, 2-OMe, 2-O2N-4-Cl, 4-COMe] showed excellent activity against a panel of microorganisms. The newly synthesized compounds were characterized using IR, 1H- NMR, 13CNMR and mass Anal. This study involved multiple reactions and reactants, such as 4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine (cas: 2272-40-4Application In Synthesis of 4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine).
4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine (cas: 2272-40-4) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control.Application In Synthesis of 4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics