Hein, Samuel J. et al. published their research in Chemical Science in 2017 | CAS: 1186603-47-3

5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.Recommanded Product: 5-Chloro-2-(phenylethynyl)benzaldehyde

Rapid access to substituted 2-naphthyne intermediates via the benzannulation of halogenated silylalkynes was written by Hein, Samuel J.;Lehnherr, Dan;Dichtel, William R.. And the article was included in Chemical Science in 2017.Recommanded Product: 5-Chloro-2-(phenylethynyl)benzaldehyde The following contents are mentioned in the article:

Here a general synthetic strategy was reported to access 2-naphthyne precursors through an Asao-Yamamoto benzannulation of ortho-(phenylethynyl)benzaldehydes with halo-silylalkynes. This transformation provided 2-halo-3-(trimethylsilyl)-naphthalenes such as I [R1 = H, n-Bu, Cl, etc.; R2 = F, Cl, OC(O)C5H11, etc.; X = I, Br] with complete regioselectivity. These naphthalene products I underwent desilylation/dehalogenation in the presence of fluoride ion to generate the corresponding 2-naphthyne intermediates, as evidenced by furan trapping expts, which in turn afforded [2.2.1]oxabicyclic alkenes II [R1 = R2 = H, n-Bu, Cl; R1 = Br, R2 = H]. When these 2-naphthynes were generated in the presence of a copper catalyst, they underwent polymerization to afford ortho-naphthalene oligomers, 2,3,8,9,14,15-hexabutyltrinaphthylene and tetrabutylbinaphthalene III selectively by varying the catalyst loading and reaction temperature The efficiency, mild conditions and versatility of the naphthalene products and naphthyne intermediates will provide efficient access to many new functional aromatic systems. This study involved multiple reactions and reactants, such as 5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3Recommanded Product: 5-Chloro-2-(phenylethynyl)benzaldehyde).

5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.Recommanded Product: 5-Chloro-2-(phenylethynyl)benzaldehyde

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics