Green, fast and simple dispersive liquid-liquid microextraction method by using hydrophobic deep eutectic solvent for analysis of folic acid in fortified flour samples before liquid chromatography determination was written by Faraji, Mohammad;Mahmoodi-Maymand, Masoumeh;Dastmalchi, Farnaz. And the article was included in Food Chemistry in 2020.Electric Literature of C25H54ClN The following contents are mentioned in the article:
A fast, simple, sensitive, and efficient vortex-assisted dispersive liquid-liquid microextraction method (VA-DES-DLME) was developed based on hydrophobic deep eutectic solvent for extraction of folic acid from flour samples followed by HPLC determination Hydrophobic DES was prepared by mixing amylalc. as a hydrogen bond donor and methyltriocthylammonium chloride as a hydrogen bond acceptor. Factors affecting DLLME were considered and optimized. In optimal conditions, the calibration curve was linear in the range 5.0-500 ng g-1 with a correlation coefficient higher than 0.99. The limit of detection (LOD) and the limit of quantification (LOQ) were 1.0 and 3.0 ng g-1, resp. The intra-day and inter-day precision at concentrations of 10 and 100 ng g-1 were less than 8%. Finally, application of the proposed procedure was investigated by folic acid anal. in flour samples and the relative recoveries obtained were acceptable (Recovery ≥ 90%). This study involved multiple reactions and reactants, such as N-Methyl-N,N-dioctyloctan-1-aminium chloride (cas: 5137-55-3Electric Literature of C25H54ClN).
N-Methyl-N,N-dioctyloctan-1-aminium chloride (cas: 5137-55-3) belongs to organic chlorides. Organochlorines are organic compounds having multiple chlorine atoms. They were the first synthetic pesticides that were used in agriculture. They are resistant to most microbial and chemical degradations. Organochlorine compounds are lipophylic, meaning they are more soluble in fat than in water. This gives them a high tenancy to accumulate in the food chain (biomagnification).Electric Literature of C25H54ClN
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics