Newby, James A. published the artcileDesign and Application of a Low-Temperature Continuous Flow Chemistry Platform, Name: (4-Chloro-2-fluoro-3-methoxyphenyl)boronic acid, the publication is Organic Process Research & Development (2014), 18(10), 1211-1220, database is CAplus.
A flow reactor platform technol. applicable to a broad range of low temperature chem. is reported. The newly developed system captures the essence of running low temperature reactions in batch and represents this as a series of five flow coils, each with independently variable volume The system was initially applied to the functionalization of alkynes, Grignard addition reactions, heterocycle functionalization, and heteroatom acetylation. This new platform has then been used in the preparation of a 20-compound library of polysubstituted, fluorine-containing aromatic substrates from a sequential metalation-quench procedure and can be readily adapted to provide gaseous electrophile inputs such as carbon dioxide using a tube-in-tube reactor.
Organic Process Research & Development published new progress about 944129-07-1. 944129-07-1 belongs to chlorides-buliding-blocks, auxiliary class Fluoride,Chloride,Boronic acid and ester,Benzene,Ether,Boronic Acids,Boronic acid and ester,, name is (4-Chloro-2-fluoro-3-methoxyphenyl)boronic acid, and the molecular formula is C7H7BClFO3, Name: (4-Chloro-2-fluoro-3-methoxyphenyl)boronic acid.
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