Gleave, Robert J. published the artcileSynthesis and evaluation of 3-amino-6-aryl-pyridazines as selective CB2 agonists for the treatment of inflammatory pain, Name: 2-Chloro-4-methylphenylboronic acid, the publication is Bioorganic & Medicinal Chemistry Letters (2010), 20(2), 465-468, database is CAplus and MEDLINE.
A series of 3-amino-6-aryl-pyridazines have been identified as CB2 agonists with high efficacy and selectivity against the CB1 receptor. Details of the investigation of structure-activity relationships (SAR) are disclosed, which led to the identification of pyridazine analog I, a compound with high potency in an in vivo model of inflammatory pain.
Bioorganic & Medicinal Chemistry Letters published new progress about 145349-62-8. 145349-62-8 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Boronic acid and ester,Benzene,Boronic Acids, name is 2-Chloro-4-methylphenylboronic acid, and the molecular formula is C7H8BClO2, Name: 2-Chloro-4-methylphenylboronic acid.
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