Yu, Fei-Le published the artcilePd-Catalyzed Allylic Alkylation of gem-Alkyl,Aryl-Disubstituted Allyl Reagents with Ketones: Diastereoselective Construction of Vicinal Tertiary and Quaternary Carbon Centers, COA of Formula: C10H15ClO3S, the publication is ACS Catalysis (2018), 8(4), 3317-3321, database is CAplus.
(E)-gem-Alkyl,aryl-disubstituted allyl carbonates can react with ketones under Pd catalysis using a com. available NHC ligand by suppressing the β-H elimination. Ketones with α-tertiary, β-quaternary carbon stereocenters were produced in high yields with high regio- and diastereoselectivities. Kinetic resolution of the reaction product via CBS reduction afforded the optically active ketone I as well as the alc. II with high enantioselectivity (S-factor = 35). The utility of the methodol. was also demonstrated by transformations of the reaction products.
ACS Catalysis published new progress about 21286-54-4. 21286-54-4 belongs to chlorides-buliding-blocks, auxiliary class Chiral,Chloride,Sulfonyl chlorides,Aliphatic cyclic hydrocarbon,Ketone, name is ((1S,4R)-7,7-Dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonyl chloride, and the molecular formula is C9H8BF3O2, COA of Formula: C10H15ClO3S.
Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics