Suliman, Fakhr Eldin O. published the artcileAnalysis of phenols in water by high-performance liquid chromatography using coumarin-6-sulfonyl chloride as a fluorogenic precolumn label, Recommanded Product: Coumarin-6-sulfonyl chloride, the publication is Journal of Chromatography A (2006), 1101(1-2), 179-184, database is CAplus and MEDLINE.
A simple, sensitive and rapid reversed-phase HPLC (RP-HPLC) method is proposed for the anal. of some environmentally important phenols in H2O. The use of coumarin-6-sulfonyl chloride (C6SCl) as a fluorescence-labeling reagent was studied. The compound reacts with phenols within 20 min under mild conditions (ambient temperature, pH 9.0) to give sulfonates that can be separated by RP-HPLC employing fluorescence detection at λ ex = 360 and λ em = 460 nm. The optimum conditions for fluorescence, derivatization and chromatog. separation were established and detection limits in the range 0.1-0.9 μg L-1 were obtained for the studied compounds The calibration curves were linear for the range 6-200 μg L-1 for phenol, 3-200 μg L-1 for 2-chlorophenol, 4-chlorophenol and 2,3,5-trichlorophenol and for the range of 3-100 μg L-1 for 2,3-dichlorophenol and 3,5-dichlorophenol. The practical applicability of the method to environmental samples was demonstrated by analyzing drinking and industrial H2O samples spiked with the phenolic compounds
Journal of Chromatography A published new progress about 10543-42-7. 10543-42-7 belongs to chlorides-buliding-blocks, auxiliary class Other Aromatic Heterocyclic,Chloride,Sulfonyl chlorides,Ester, name is Coumarin-6-sulfonyl chloride, and the molecular formula is C10H7IN2, Recommanded Product: Coumarin-6-sulfonyl chloride.
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