Mandour, A. H. published the artcileSynthesis, antimicrobial and antiaflatoxigenic activities of new coumarin derivatives, Computed Properties of 10543-42-7, the publication is Egyptian Journal of Pharmaceutical Sciences (1995), 36(1-6), 71-85, database is CAplus.
Coumarin-6-sulfonyl chloride reacted with m-or p- aminoacetophenone to give sulfonamide derivatives, which in turn were condensed with semicarbazide hydrochloride to give semicarbazone derivatives Also some sulfonamides reacted with thiosemicarbazide to give thiosemicarbazone derivatives Oxidative cyclization of semicarbazones or thiosemicarbazones using thionylchloride led to the formation of 4-substituted-1,2,3-thiadiazoles using selenium dioxide led to the formation of 4-substituted-1,2,3- selenadiazoles . Also, 4-[6-nitrocoumarin-3- sulfonamido-N-(m or p-phenylene)] -1,2,3-thiadiazoles and -1,2,3-selenadiazoles. The antimicrobial and antiaflatoxigenic activities of thiadiazoles and selenadiazoles were also investigated.
Egyptian Journal of Pharmaceutical Sciences published new progress about 10543-42-7. 10543-42-7 belongs to chlorides-buliding-blocks, auxiliary class Other Aromatic Heterocyclic,Chloride,Sulfonyl chlorides,Ester, name is Coumarin-6-sulfonyl chloride, and the molecular formula is C9H5ClO4S, Computed Properties of 10543-42-7.
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